A Small Molecule, Lys-Ala-7-amido-4-methylcoumarin, Facilitates RNA Dimer Maturation of a Stem−Loop 1 Transcript in Vitro: Structure−Activity Relationship of the Activator†

Biochemistry ◽  
2008 ◽  
Vol 47 (31) ◽  
pp. 8148-8156 ◽  
Author(s):  
Janet Chung ◽  
Anwer Mujeeb ◽  
Yongying Jiang ◽  
Christophe Guilbert ◽  
Mrunal Pendke ◽  
...  
Keyword(s):  
Small Molecule ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Stem Loop ◽  
Structure Activity ◽  
Rna Dimer ◽  
Relationship Of

scholarly journals From in vitro to in cellulo: structure–activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa

2014 ◽  
Vol 12 (32) ◽  
pp. 6094-6104 ◽  
Author(s):  
Michael P. Storz ◽  
Giuseppe Allegretta ◽  
Benjamin Kirsch ◽  
Martin Empting ◽  
Rolf W. Hartmann
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Relationship Of ◽  
Derivatives Of

More than 60 derivatives of (2-nitrophenyl)methanol were synthesized and evaluated regarding their potency to inhibit PqsD. In vitro and in cellulo structure–activity relationships were derived.

scholarly journals Discovery and Structure Activity Relationship of Small Molecule Inhibitors of Toxic β-Amyloid-42 Fibril Formation

2012 ◽  
Vol 287 (41) ◽  
pp. 34786-34800 ◽  
Author(s):  
Heiko Kroth ◽  
Annalisa Ansaloni ◽  
Yvan Varisco ◽  
Asad Jan ◽  
Nampally Sreenivasachary ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Structure Activity Relationship ◽  
Fibril Formation ◽  
Activity Relationship ◽  
Structure Activity ◽  
Β Amyloid ◽  
Relationship Of

Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo

2006 ◽  
Vol 49 (3) ◽  
pp. 1165-1181 ◽  
Author(s):  
Michael D. Wendt ◽  
Wang Shen ◽  
Aaron Kunzer ◽  
William J. McClellan ◽  
Milan Bruncko ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

scholarly journals In vitro structure–activity relationship of Re-cyclized octreotide analogues

2010 ◽  
Vol 37 (5) ◽  
pp. 527-537 ◽  
Author(s):  
Shorouk F. Dannoon ◽  
Heather M. Bigott-Hennkens ◽  
Lixin Ma ◽  
Fabio Gallazzi ◽  
Michael R. Lewis ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

In vitro antifungal evaluation and structure-activity relationship of diphenyl diselenide and synthetic analogues

Mycoses ◽  
2011 ◽  
Vol 54 (5) ◽  
pp. e572-e576 ◽  
Author(s):  
Érico Silva Loreto ◽  
Débora Alves Nunes Mario ◽  
Janio Morais Santurio ◽  
Sydney Hartz Alves ◽  
Cristina Wayne Nogueira ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Diphenyl Diselenide ◽  
Synthetic Analogues ◽  
Structure Activity ◽  
Relationship Of
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