Isomerization of a Single Aspartyl Residue of Anti-Epidermal Growth Factor Receptor Immunoglobulin γ2 Antibody Highlights the Role Avidity Plays in Antibody Activity

Douglas S. Rehder; Dirk Chelius; Arnold McAuley; Thomas M. Dillon; Gang Xiao; Jill Crouse-Zeineddini; Louisa Vardanyan; Natalie Perico; Venkat Mukku; David N. Brems; Masazumi Matsumura; Pavel V. Bondarenko

doi:10.1021/bi7018223

Isomerization of a Single Aspartyl Residue of Anti-Epidermal Growth Factor Receptor Immunoglobulin γ2 Antibody Highlights the Role Avidity Plays in Antibody Activity

Biochemistry ◽

10.1021/bi7018223 ◽

2008 ◽

Vol 47 (8) ◽

pp. 2518-2530 ◽

Cited By ~ 75

Author(s):

Douglas S. Rehder ◽

Dirk Chelius ◽

Arnold McAuley ◽

Thomas M. Dillon ◽

Gang Xiao ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Antibody Activity ◽

Epidermal Growth ◽

Aspartyl Residue

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Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

Yearbook of Neurology and Neurosurgery ◽

10.1016/j.yneu.2011.04.060 ◽

2011 ◽

Vol 2011 ◽

pp. 141-143

Author(s):

J. Uhm

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Progression Free Survival ◽

Newly Diagnosed ◽

Peptide Vaccination ◽

Free Survival ◽

Newly Diagnosed Glioblastoma ◽

Epidermal Growth

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Rotavirus infection induces increased chloride secretion, altered barrier function and epidermal growth factor receptor (EGF-R) polyubiquitination in intestinal epithelial cells (IEC)

Gastroenterology ◽

10.1016/s0016-5085(01)83508-3 ◽

2001 ◽

Vol 120 (5) ◽

pp. A704-A705

Author(s):

S RESTALENERT ◽

K BARRETT

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Epithelial Cells ◽

Barrier Function ◽

Intestinal Epithelial Cells ◽

Growth Factor Receptor ◽

Chloride Secretion ◽

Intestinal Epithelial ◽

Epidermal Growth

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Effect of Helicobacter pylori infection on epidermal growth factor receptor (EGFR) expression and cell proliferation of gastric epithelial mucosa

Gastroenterology ◽

10.1016/s0016-5085(01)83331-x ◽

2001 ◽

Vol 120 (5) ◽

pp. A669-A670

Author(s):

Z UNGER ◽

B MOLNAR ◽

M EBERT ◽

L PRONAI ◽

P MALFERTHEINER ◽

...

Keyword(s):

Cell Proliferation ◽

Helicobacter Pylori ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Helicobacter Pylori Infection ◽

Egfr Expression ◽

Epidermal Growth

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Epidermal growth factor receptor mRNA expression level predicts for survival in metastatic colorectal tumors

Gastroenterology ◽

10.1016/s0016-5085(01)82462-8 ◽

2001 ◽

Vol 120 (5) ◽

pp. A496-A496

Author(s):

J STOEHLMACHER ◽

J BRABENDER ◽

Y SHIROTA ◽

K DANENBERG ◽

P DANENBERG ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Mrna Expression ◽

Growth Factor Receptor ◽

Expression Level ◽

Mrna Expression Level ◽

Colorectal Tumors ◽

Receptor Mrna ◽

Epidermal Growth

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263: Expression of Epidermal Growth Factor Receptor and Platelet-Derived Growth Factor Receptor in Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)32530-8 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 87-88

Author(s):

Chang Wook Jeong ◽

Cheol Kwak ◽

Gheeyoung Choe ◽

Sang Eun Lee

Keyword(s):

Prostate Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Platelet Derived Growth Factor ◽

Epidermal Growth

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Epidermal Growth Factor Receptor Expression Status in Lung Cancer Correlates With Its Mutation

Yearbook of Pathology and Laboratory Medicine ◽

10.1016/s1077-9108(08)70317-7 ◽

2007 ◽

Vol 2007 ◽

pp. 106-107

Author(s):

P.A. Bejarano

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Receptor Expression ◽

Epidermal Growth ◽

Expression Status

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Cytomorphological Correlates of Epidermal Growth Factor Receptor Mutations in Lung Carcinoma

Yearbook of Pathology and Laboratory Medicine ◽

10.1016/s1077-9108(08)70687-x ◽

2008 ◽

Vol 2008 ◽

pp. 250-252

Author(s):

M. Vazquez

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Lung Carcinoma ◽

Growth Factor Receptor ◽

Epidermal Growth

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Ionizing Radiation Enhances Matrix Metalloproteinase-2 Secretion and Invasion of Glioma Cells through Src/Epidermal Growth Factor Receptor-Mediated p38/Akt and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways

Yearbook of Pathology and Laboratory Medicine ◽

10.1016/s1077-9108(08)70678-9 ◽

2008 ◽

Vol 2008 ◽

pp. 231-233

Author(s):

C. Horbinski

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Matrix Metalloproteinase ◽

Growth Factor Receptor ◽

Glioma Cells ◽

Akt Signaling ◽

Matrix Metalloproteinase 2 ◽

Phosphatidylinositol 3 Kinase ◽

Epidermal Growth

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Epidermal growth factor receptor-targeted therapy for pancreatic cancer

Seminars in Oncology ◽

10.1053/sonc.2002.35645 ◽

2002 ◽

Vol 29 (5 Suppl 14) ◽

pp. 31-37 ◽

Cited By ~ 80

Author(s):

Henry Q. Xiong ◽

James L. Abbruzzese

Keyword(s):

Pancreatic Cancer ◽

Epidermal Growth Factor Receptor ◽

Targeted Therapy ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Epidermal Growth

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IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer

Seminars in Oncology ◽

10.1053/sonc.2002.35644 ◽

2002 ◽

Vol 29 (5 Suppl 14) ◽

pp. 18-30 ◽

Cited By ~ 58

Author(s):

Roy S. Herbst ◽

Waun Ki Hong

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Head And Neck Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Head And Neck ◽

Neck Cancer ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Monoclonal Antibody

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