Mapping Key Regions of the RXFP2 Low-Density Lipoprotein Class-A Module That Are Involved in Signal Activation

Roy C. K. Kong; Ross A. D. Bathgate; Shoni Bruell; John D. Wade; Paul R. Gooley; Emma J. Petrie

doi:10.1021/bi500797d

Mapping Key Regions of the RXFP2 Low-Density Lipoprotein Class-A Module That Are Involved in Signal Activation

Biochemistry ◽

10.1021/bi500797d ◽

2014 ◽

Vol 53 (28) ◽

pp. 4537-4548 ◽

Cited By ~ 10

Author(s):

Roy C. K. Kong ◽

Ross A. D. Bathgate ◽

Shoni Bruell ◽

John D. Wade ◽

Paul R. Gooley ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Class ◽

Class A ◽

Signal Activation

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A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain

Gene ◽

10.1016/s0378-1119(02)00438-9 ◽

2002 ◽

Vol 286 (2) ◽

pp. 223-231 ◽

Cited By ~ 46

Author(s):

Heidi Stöhr ◽

Claudia Berger ◽

Susanne Fröhlich ◽

Bernhard H.F. Weber

Keyword(s):

Transmembrane Protein ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Gene Encoding ◽

Lipoprotein Class ◽

Class A ◽

Novel Gene ◽

Alternatively Spliced

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Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules

Frontiers in Endocrinology ◽

10.3389/fendo.2013.00171 ◽

2013 ◽

Vol 4 ◽

Cited By ~ 16

Author(s):

Shoni Bruell ◽

Roy C. K. Kong ◽

Emma J. Petrie ◽

Brad Hoare ◽

John D. Wade ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Class ◽

Class A

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Characterization of Novel Splice Variants of LGR7 and LGR8 Reveals That Receptor Signaling Is Mediated by Their Unique Low Density Lipoprotein Class A Modules

Journal of Biological Chemistry ◽

10.1074/jbc.m602728200 ◽

2006 ◽

Vol 281 (46) ◽

pp. 34942-34954 ◽

Cited By ~ 102

Author(s):

Daniel J. Scott ◽

Sharon Layfield ◽

Yan Yan ◽

Satoko Sudo ◽

Aaron J. W. Hsueh ◽

...

Keyword(s):

Splice Variants ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Receptor Signaling ◽

Lipoprotein Class ◽

Class A

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The Relaxin Receptor (RXFP1) Utilizes Hydrophobic Moieties on a Signaling Surface of Its N-terminal Low Density Lipoprotein Class A Module to Mediate Receptor Activation

Journal of Biological Chemistry ◽

10.1074/jbc.m113.499640 ◽

2013 ◽

Vol 288 (39) ◽

pp. 28138-28151 ◽

Cited By ~ 20

Author(s):

Roy C. K. Kong ◽

Emma J. Petrie ◽

Biswaranjan Mohanty ◽

Jason Ling ◽

Jeremy C. Y. Lee ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Receptor Activation ◽

Low Density ◽

Lipoprotein Class ◽

Class A ◽

Relaxin Receptor

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The Human LGR7 Low-Density Lipoprotein Class A Module Requires Calcium for Structure

Annals of the New York Academy of Sciences ◽

10.1196/annals.1282.006 ◽

2005 ◽

Vol 1041 (1) ◽

pp. 27-34 ◽

Cited By ~ 12

Author(s):

EMMA J. HOPKINS ◽

ROSS A. BATHGATE ◽

PAUL R. GOOLEY

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Class ◽

Class A

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Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)33452-0 ◽

2000 ◽

Vol 41 (9) ◽

pp. 1402-1409 ◽

Cited By ~ 5

Author(s):

Nicole Herijgers ◽

Menno P.J. de Winther ◽

Miranda Van Eck ◽

Louis M. Havekes ◽

Marten H. Hofker ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Scavenger Receptor ◽

Lipoprotein Metabolism ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Class A ◽

Scavenger Receptor Class ◽

Density Lipoprotein Receptor ◽

Bone Marrow Derived Cells

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A low-density lipoprotein receptor (LDLR) class A domain-containing C-type lectin from Litopenaeus vannamei plays opposite roles in antibacterial and antiviral responses

Developmental & Comparative Immunology ◽

10.1016/j.dci.2018.11.002 ◽

2019 ◽

Vol 92 ◽

pp. 29-34 ◽

Cited By ~ 8

Author(s):

Zhiwei Liang ◽

Linwei Yang ◽

Jiefu Zheng ◽

Hongliang Zuo ◽

Shaoping Weng ◽

...

Keyword(s):

Litopenaeus Vannamei ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Antiviral Responses ◽

Class A ◽

Density Lipoprotein Receptor

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Lysophosphatidic acid-induced oxidized low-density lipoprotein uptake is class A scavenger receptor-dependent in macrophages

Prostaglandins & Other Lipid Mediators ◽

10.1016/j.prostaglandins.2008.05.002 ◽

2008 ◽

Vol 87 (1-4) ◽

pp. 20-25 ◽

Cited By ~ 28

Author(s):

Chi-Lun Chang ◽

Hsien-Yeh Hsu ◽

Hong-Yu Lin ◽

Wenchang Chiang ◽

Hsinyu Lee

Keyword(s):

Lysophosphatidic Acid ◽

Low Density Lipoprotein ◽

Scavenger Receptor ◽

Density Lipoprotein ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Class A ◽

Lipoprotein Uptake ◽

Class A Scavenger Receptor

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Downregulation of low‐density lipoprotein receptor class A domain‐containing protein 4 ( Ldlrad4 ) in the liver of rats treated with nongenotoxic hepatocarcinogen to induce transforming growth factor β signaling promoting cell proliferation and suppressing apoptosis in early hepatocarcinogenesis

Journal of Applied Toxicology ◽

10.1002/jat.3998 ◽

2020 ◽

Vol 40 (11) ◽

pp. 1467-1479

Author(s):

Yuko Ito ◽

Kota Nakajima ◽

Yasunori Masubuchi ◽

Satomi Kikuchi ◽

Hiromu Okano ◽

...

Keyword(s):

Cell Proliferation ◽

Growth Factor ◽

Transforming Growth Factor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Transforming Growth Factor Β ◽

Low Density ◽

Lipoprotein Receptor ◽

Class A ◽

Density Lipoprotein Receptor

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Class A Scavenger Receptor Up-regulation in Smooth Muscle Cells by Oxidized Low Density Lipoprotein

Journal of Biological Chemistry ◽

10.1074/jbc.275.23.17661 ◽

2000 ◽

Vol 275 (23) ◽

pp. 17661-17670 ◽

Cited By ~ 69

Author(s):

Michele Mietus-Snyder ◽

Maya S. Gowri ◽

Robert E. Pitas

Keyword(s):

Smooth Muscle ◽

Smooth Muscle Cells ◽

Low Density Lipoprotein ◽

Scavenger Receptor ◽

Density Lipoprotein ◽

Muscle Cells ◽

Low Density ◽

Oxidized Low Density Lipoprotein ◽

Class A ◽

Class A Scavenger Receptor

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