NMR Studies of DNA Support the Role of Pre-Existing Minor Groove Variations in Nucleosome Indirect Readout

Biochemistry ◽  
2014 ◽  
Vol 53 (35) ◽  
pp. 5601-5612 ◽  
Author(s):  
Xiaoqian Xu ◽  
Akli Ben Imeddourene ◽  
Loussiné Zargarian ◽  
Nicolas Foloppe ◽  
Olivier Mauffret ◽  
...  
Keyword(s):  
Minor Groove ◽  
Nmr Studies ◽  
Indirect Readout

scholarly journals The Role of the Minor Groove Substituents in Indirect Readout of DNA Sequence by 434 Repressor

2003 ◽  
Vol 278 (15) ◽  
pp. 12955-12960 ◽  
Author(s):  
Steven A. Mauro ◽  
David Pawlowski ◽  
Gerald B. Koudelka
Keyword(s):  
Dna Sequence ◽  
Minor Groove ◽  
Indirect Readout ◽  
434 Repressor

scholarly journals Catalytic Systems Based on Cp2ZrX2 (X = Cl, H), Organoaluminum Compounds and Perfluorophenylboranes: Role of Zr,Zr- and Zr,Al-Hydride Intermediates in Alkene Dimerization and Oligomerization

Catalysts ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 39
Author(s):  
Lyudmila V. Parfenova ◽  
Pavel V. Kovyazin ◽  
Almira Kh. Bikmeeva ◽  
Eldar R. Palatov
Keyword(s):  
Diffusion Coefficients ◽  
Organoaluminum Compounds ◽  
Zirconium Hydride ◽  
Nmr Studies ◽  
Catalytic Systems ◽  
Selective Formation

The activity and chemoselectivity of the Cp2ZrCl2-XAlBui2 (X = H, Bui) and [Cp2ZrH2]2-ClAlEt2 catalytic systems activated by (Ph3C)[B(C6F5)4] or B(C6F5)3 were studied in reactions with 1-hexene. The activation of the systems by B(C6F5)3 resulted in the selective formation of head-to-tail alkene dimers in up to 93% yields. NMR studies of the reactions of Zr complexes with organoaluminum compounds (OACs) and boron activators showed the formation of Zr,Zr- and Zr,Al-hydride intermediates, for which diffusion coefficients, hydrodynamic radii, and volumes were estimated using the diffusion ordered spectroscopy DOSY. Bis-zirconium hydride clusters of type x[Cp2ZrH2∙Cp2ZrHCl∙ClAlR2]∙yRnAl(C6F5)3−n were found to be the key intermediates of alkene dimerization, whereas cationic Zr,Al-hydrides led to the formation of oligomers.

scholarly journals Role of Minor Groove Width and Hydration Pattern on Amsacrine Interaction with DNA

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69933 ◽  
Author(s):  
Deepak K. Jangir ◽  
Suman Kundu ◽  
Ranjana Mehrotra
Keyword(s):  
Minor Groove ◽  
Groove Width

scholarly journals On Stereocontrol in Organocatalytic α-Chlorinations of Aldehydes

2021 ◽  
Author(s):  
Sebastian Ponath ◽  
Chetan Joshi ◽  
Amy T. Merrill ◽  
Volker Schmidts ◽  
Kim Greis ◽  
...  
Keyword(s):  
Ion Mobility ◽  
Resting State ◽  
Comprehensive Analysis ◽  
Ion Mobility Mass Spectrometry ◽  
Concentration Profiles ◽  
Nmr Studies ◽  
Isotope Studies ◽  
Configuration And Conformation

A comprehensive analysis of the organocatalytic α‐chlorination of aldehydes with N‐chloroimides and differ‐ ent catalysts is presented. For this reaction, alternate mechanisms were proposed that differ in the role of resting state intermediates and the rationalization of the observed enantioselectivity. This manuscript aims at resolving these funda‐ mental questions on the basis of rigorous structural characterization of intermediates (configuration and conformation), NMR studies, ion mobility‐mass spectrometry, concentration profiles, isotope studies, and DFT calculations. <br>

Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: Clarifying the role of N3-methyladenine

2014 ◽  
Vol 759 ◽  
pp. 45-51 ◽  
Author(s):  
Paola Monti ◽  
Giorgia Foggetti ◽  
Paola Menichini ◽  
Alberto Inga ◽  
Barry Gold ◽  
...  
Keyword(s):  
Biological Effects ◽  
Minor Groove ◽  
A Minor

Stability and Polymerase Recognition of Pyridine Nucleobase Analogues: Role of Minor-Groove H-Bond Acceptors

2006 ◽  
Vol 118 (46) ◽  
pp. 7973-7976 ◽  
Author(s):  
Yoonkyung Kim ◽  
Aaron M. Leconte ◽  
Yoshiyuki Hari ◽  
Floyd E. Romesberg
Keyword(s):  
Minor Groove

scholarly journals Contribution of dihydrouridine in folding of the D-arm in tRNA

2015 ◽  
Vol 13 (17) ◽  
pp. 4960-4966 ◽  
Author(s):  
N. Dyubankova ◽  
E. Sochacka ◽  
K. Kraszewska ◽  
B. Nawrot ◽  
P. Herdewijn ◽  
...  
Keyword(s):  
Crucial Role ◽  
Nmr Studies

NMR studies of the D-arm of tRNAiMet revealed the crucial role of dihydrouridine nucleoside in folding of the oligo.

Short Lexitropsin that Recognizes the DNA Minor Groove at 5‘-ACTAGT-3‘:  Understanding the Role of Isopropyl-thiazole

2004 ◽  
Vol 126 (36) ◽  
pp. 11338-11349 ◽  
Author(s):  
Nahoum G. Anthony ◽  
Blair F. Johnston ◽  
Abedawn I. Khalaf ◽  
Simon P. MacKay ◽  
John A. Parkinson ◽  
...  
Keyword(s):  
Minor Groove ◽  
Dna Minor Groove
Sign in / Sign up

Export Citation Format

Share Document