Effects of Calcium Binding and the Hypertrophic Cardiomyopathy A8V Mutation on the Dynamic Equilibrium between Closed and Open Conformations of the Regulatory N-Domain of Isolated Cardiac Troponin C

Biochemistry ◽  
2013 ◽  
Vol 52 (11) ◽  
pp. 1950-1962 ◽  
Author(s):  
Nicole M. Cordina ◽  
Chu K. Liew ◽  
David A. Gell ◽  
Piotr G. Fajer ◽  
Joel P. Mackay ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Calcium Binding ◽  
Cardiac Troponin ◽  
Dynamic Equilibrium ◽  
Troponin C ◽  
Cardiac Troponin C

scholarly journals Mutation of the high affinity calcium binding sites in cardiac troponin C.

1992 ◽  
Vol 267 (2) ◽  
pp. 825-831 ◽  
Author(s):  
J C Negele ◽  
D G Dotson ◽  
W Liu ◽  
H L Sweeney ◽  
J A Putkey
Keyword(s):  
Binding Sites ◽  
Calcium Binding ◽  
Cardiac Troponin ◽  
Troponin C ◽  
High Affinity ◽  
Cardiac Troponin C ◽  
Calcium Binding Sites

scholarly journals Hypertrophic Cardiomyopathy Cardiac Troponin C Mutations Differentially Affect Slow Skeletal and Cardiac Muscle Regulation

2017 ◽  
Vol 8 ◽  
Author(s):  
Tiago Veltri ◽  
Maicon Landim-Vieira ◽  
Michelle S. Parvatiyar ◽  
David Gonzalez-Martinez ◽  
Karissa M. Dieseldorff Jones ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Cardiac Muscle ◽  
Cardiac Troponin ◽  
Troponin C ◽  
Muscle Regulation ◽  
Cardiac Troponin C ◽  
Cardiac Muscle Regulation

scholarly journals A Mutation inTNNC1-encoded Cardiac Troponin C, TNNC1-A31S, Predisposes to Hypertrophic Cardiomyopathy and Ventricular Fibrillation

2012 ◽  
Vol 287 (38) ◽  
pp. 31845-31855 ◽  
Author(s):  
Michelle S. Parvatiyar ◽  
Andrew P. Landstrom ◽  
Cicero Figueiredo-Freitas ◽  
James D. Potter ◽  
Michael J. Ackerman ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Ventricular Fibrillation ◽  
Cardiac Troponin ◽  
Troponin C ◽  
Cardiac Troponin C

scholarly journals A Novel Mutation in TNNC1-ENCODED Cardiac Troponin C Predisposes to Hypertrophic Cardiomyopathy and Recurrent Episodes of Aborted Sudden Cardiac Death

2011 ◽  
Vol 100 (3) ◽  
pp. 114a
Author(s):  
Michelle S. Parvatiyar ◽  
Andrew P. Landstrom ◽  
Jose Renato Pinto ◽  
Jingsheng Liang ◽  
Michael J. Ackerman ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Sudden Cardiac Death ◽  
Cardiac Troponin ◽  
Cardiac Death ◽  
Novel Mutation ◽  
Troponin C ◽  
Cardiac Troponin C
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