Different Modes of Carbon Monoxide Binding to Acetyl-CoA Synthase and the Role of a Conserved Phenylalanine in the Coordination Environment of Nickel

Biochemistry ◽  
2013 ◽  
Vol 52 (10) ◽  
pp. 1705-1716 ◽  
Author(s):  
Simonida Gencic ◽  
Kayla Kelly ◽  
Selamawit Ghebreamlak ◽  
Evert C. Duin ◽  
David A. Grahame
Keyword(s):  
Carbon Monoxide ◽  
Acetyl Coa ◽  
Coordination Environment ◽  
Carbon Monoxide Binding

Infrared Studies of Carbon Monoxide Binding to Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase fromMoorella thermoacetica†

Biochemistry ◽  
2003 ◽  
Vol 42 (50) ◽  
pp. 14822-14830 ◽  
Author(s):  
Jingyi Chen ◽  
Shan Huang ◽  
Javier Seravalli ◽  
Howard Gutzman, ◽  
Derrick J. Swartz ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Dehydrogenase ◽  
Acetyl Coa ◽  
Infrared Studies ◽  
Carbon Monoxide Binding

scholarly journals Kinetics of carbon monoxide binding to monomeric hemoproteins. Role of the proximal histidine.

1985 ◽  
Vol 260 (7) ◽  
pp. 4151-4155 ◽  
Author(s):  
M Coletta ◽  
P Ascenzi ◽  
T G Traylor ◽  
M Brunori
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Binding ◽  
Kinetics Of

scholarly journals Role of copper during carbon monoxide binding to terminal oxidases

FEBS Letters ◽  
1998 ◽  
Vol 429 (2) ◽  
pp. 216-220 ◽  
Author(s):  
Maria S Muntyan ◽  
Bernd Ludwig ◽  
Irmela Zickermann ◽  
Nataliya P Starshinova
Keyword(s):  
Carbon Monoxide ◽  
Terminal Oxidases ◽  
Carbon Monoxide Binding

The Role of the Second Coordination Sphere of [Ni(PCy2NBz2)2](BF4)2in Reversible Carbon Monoxide Binding

2008 ◽  
Vol 130 (3) ◽  
pp. 1061-1068 ◽  
Author(s):  
Aaron D. Wilson ◽  
Kendra Fraze ◽  
Brendan Twamley ◽  
Susie M. Miller ◽  
Daniel L. DuBois ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Coordination Sphere ◽  
Carbon Monoxide Binding ◽  
Second Coordination Sphere

scholarly journals Evolutionary history of carbon monoxide dehydrogenase/acetyl-CoA synthase, one of the oldest enzymatic complexes

2018 ◽  
Vol 115 (6) ◽  
pp. E1166-E1173 ◽  
Author(s):  
Panagiotis S. Adam ◽  
Guillaume Borrel ◽  
Simonetta Gribaldo
Keyword(s):  
Carbon Monoxide ◽  
Evolutionary History ◽  
Carbon Fixation ◽  
Functional Characterization ◽  
Carbon Monoxide Dehydrogenase ◽  
Evolutionary Analysis ◽  
Acetyl Coa ◽  
Universal Common Ancestor ◽  
History Of

Carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) is a five-subunit enzyme complex responsible for the carbonyl branch of the Wood–Ljungdahl (WL) pathway, considered one of the most ancient metabolisms for anaerobic carbon fixation, but its origin and evolutionary history have been unclear. While traditionally associated with methanogens and acetogens, the presence of CODH/ACS homologs has been reported in a large number of uncultured anaerobic lineages. Here, we have carried out an exhaustive phylogenomic study of CODH/ACS in over 6,400 archaeal and bacterial genomes. The identification of complete and likely functional CODH/ACS complexes in these genomes significantly expands its distribution in microbial lineages. The CODH/ACS complex displays astounding conservation and vertical inheritance over geological times. Rare intradomain and interdomain transfer events might tie into important functional transitions, including the acquisition of CODH/ACS in some archaeal methanogens not known to fix carbon, the tinkering of the complex in a clade of model bacterial acetogens, or emergence of archaeal–bacterial hybrid complexes. Once these transfers were clearly identified, our results allowed us to infer the presence of a CODH/ACS complex with at least four subunits in the last universal common ancestor (LUCA). Different scenarios on the possible role of ancestral CODH/ACS are discussed. Despite common assumptions, all are equally compatible with an autotrophic, mixotrophic, or heterotrophic LUCA. Functional characterization of CODH/ACS from a larger spectrum of bacterial and archaeal lineages and detailed evolutionary analysis of the WL methyl branch will help resolve this issue.

The role of rice bran extract on acetyl CoA carboxylase in liver of rats fed a high-fat diet

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
C Charkhonpunya ◽  
S Sireeratawong ◽  
S Komindr ◽  
N Lerdvuthisopon
Keyword(s):  
Rice Bran ◽  
High Fat Diet ◽  
Acetyl Coa Carboxylase ◽  
High Fat ◽  
Acetyl Coa ◽  
Rice Bran Extract
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