Comparative Molecular Dynamics Study of Human Islet Amyloid Polypeptide (IAPP) and Rat IAPP Oligomers

Biochemistry ◽  
2013 ◽  
Vol 52 (6) ◽  
pp. 1089-1100 ◽  
Author(s):  
Guizhao Liang ◽  
Jun Zhao ◽  
Xiang Yu ◽  
Jie Zheng
Keyword(s):  
Molecular Dynamics ◽  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Dynamics of the conformational transitions during the dimerization of an intrinsically disordered peptide: a case study on the human islet amyloid polypeptide fragment

2016 ◽  
Vol 18 (43) ◽  
pp. 29892-29904 ◽  
Author(s):  
Qin Qiao ◽  
Ruxi Qi ◽  
Guanghong Wei ◽  
Xuhui Huang
Keyword(s):  
Molecular Dynamics ◽  
Islet Amyloid Polypeptide ◽  
Conformational Transitions ◽  
Human Islet ◽  
Islet Amyloid ◽  
Intrinsically Disordered ◽  
Human Islet Amyloid Polypeptide ◽  
Intrinsically Disordered Peptide ◽  
Dynamics Simulations

Dimerization pathways of the human islet amyloid polypeptide fragment are elucidated from extensive molecular dynamics simulations.

Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans

Diabetes ◽  
1994 ◽  
Vol 43 (5) ◽  
pp. 640-644 ◽  
Author(s):  
E. J. de Koning ◽  
J. W. Hoppener ◽  
J. S. Verbeek ◽  
C. Oosterwijk ◽  
K. L. van Hulst ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death

Biochimie ◽  
2020 ◽  
Vol 170 ◽  
pp. 26-35 ◽  
Author(s):  
Shadai Salazar Vazquez ◽  
Bertrand Blondeau ◽  
Pierre Cattan ◽  
Mathieu Armanet ◽  
Ghislaine Guillemain ◽  
...  
Keyword(s):  
Cell Death ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide
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