scholarly journals Curvature Forces in Membrane Lipid–Protein Interactions

Biochemistry ◽  
2012 ◽  
Vol 51 (49) ◽  
pp. 9782-9795 ◽  
Author(s):  
Michael F. Brown
Author(s):  
Michael F. Brown ◽  
Udeep Chawla ◽  
Suchithranga M. D. C. Perera

Symmetry ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1356
Author(s):  
Haden L. Scott ◽  
Kristen B. Kennison ◽  
Thais A. Enoki ◽  
Milka Doktorova ◽  
Jacob J. Kinnun ◽  
...  

It is well known that the lipid distribution in the bilayer leaflets of mammalian plasma membranes (PMs) is not symmetric. Despite this, model membrane studies have largely relied on chemically symmetric model membranes for the study of lipid–lipid and lipid–protein interactions. This is primarily due to the difficulty in preparing stable, asymmetric model membranes that are amenable to biophysical studies. However, in the last 20 years, efforts have been made in producing more biologically faithful model membranes. Here, we review several recently developed experimental and computational techniques for the robust generation of asymmetric model membranes and highlight a new and particularly promising technique to study membrane asymmetry.


2012 ◽  
Vol 102 (3) ◽  
pp. 468a
Author(s):  
Blake Mertz ◽  
Eglof Ritter ◽  
Franz Bartl ◽  
Michael F. Brown

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