Conformational Equilibrium of N-Myristoylated cAMP-Dependent Protein Kinase A by Molecular Dynamics Simulations

Alessandro Cembran; Larry R. Masterson; Christopher L. McClendon; Susan S. Taylor; Jiali Gao; Gianluigi Veglia

doi:10.1021/bi301279f

Conformational Equilibrium of N-Myristoylated cAMP-Dependent Protein Kinase A by Molecular Dynamics Simulations

Biochemistry ◽

10.1021/bi301279f ◽

2012 ◽

Vol 51 (51) ◽

pp. 10186-10196 ◽

Cited By ~ 20

Author(s):

Alessandro Cembran ◽

Larry R. Masterson ◽

Christopher L. McClendon ◽

Susan S. Taylor ◽

Jiali Gao ◽

...

Keyword(s):

Molecular Dynamics ◽

Protein Kinase ◽

Molecular Dynamics Simulations ◽

Protein Kinase A ◽

Conformational Equilibrium ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Dynamics Simulations ◽

Kinase A

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cAMP exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A and exchange proteins directly activated by cAMP

Endocrine Abstracts ◽

10.1530/endoabs.32.p827 ◽

2013 ◽

Author(s):

Eleonora Vitali ◽

Erika Peverelli ◽

Giovanna Mantovani ◽

Elena Giardino ◽

Andrea G. Lania ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Pituitary Cells ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Different Types ◽

Dependent Protein ◽

Kinase A

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Increased expression of the RIα subunit of the cAMP-dependent protein kinase A is associated with advanced stage ovarian cancer

British Journal of Cancer ◽

10.1038/sj.bjc.6690149 ◽

1999 ◽

Vol 79 (5-6) ◽

pp. 933-939 ◽

Cited By ~ 35

Author(s):

H M McDaid ◽

M T Cairns ◽

R J Atkinson ◽

S McAleer ◽

D P Harkin ◽

...

Keyword(s):

Ovarian Cancer ◽

Protein Kinase ◽

Protein Kinase A ◽

Advanced Stage ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Kinase A

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Modulation of Regulatory and Catalytic Subunit Levels of cAMP-Dependent Protein Kinase A in Anterior Pituitary Cells in Response to Direct Activation of Protein Kinases A and C or after GnRH Stimulation

Neuroendocrinology ◽

10.1159/000127042 ◽

1995 ◽

Vol 62 (5) ◽

pp. 514-522 ◽

Cited By ~ 15

Author(s):

Ghislaine Garrel ◽

Richard Delahaye ◽

Brian A. Hemmings ◽

Raymond Counis

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Protein Kinases ◽

Anterior Pituitary ◽

Catalytic Subunit ◽

Pituitary Cells ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Kinase A

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Synergistic effects of cAMP–dependent protein kinase A and AMP-activated protein kinase on lipolysis in kinsenoside-treated C3H10T1/2 adipocytes

Phytomedicine ◽

10.1016/j.phymed.2018.06.043 ◽

2019 ◽

Vol 55 ◽

pp. 255-263 ◽

Cited By ~ 1

Author(s):

Yuan-Chii G. Lee ◽

Yuh-Mou Sue ◽

Ching-Kuo Lee ◽

Huei-Mei Huang ◽

Jhin-Jyun He ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Synergistic Effects ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Amp Activated Protein Kinase ◽

Kinase A

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Phosphorylation and activation of hamster carbamyl phosphate synthetase II by cAMP-dependent protein kinase. A novel mechanism for regulation of pyrimidine nucleotide biosynthesis.

The EMBO Journal ◽

10.1002/j.1460-2075.1985.tb04142.x ◽

1985 ◽

Vol 4 (13B) ◽

pp. 3735-3742 ◽

Cited By ~ 54

Author(s):

E.A. Carrey ◽

D.G. Campbell ◽

D.G. Hardie

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Carbamyl Phosphate ◽

Dependent Protein Kinase ◽

Nucleotide Biosynthesis ◽

Carbamyl Phosphate Synthetase ◽

Camp Dependent Protein Kinase ◽

Pyrimidine Nucleotide ◽

Dependent Protein ◽

Kinase A

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cAMP-Dependent Protein Kinase A-Stimulated Sarcoplasmic Reticulum Function in Heart Failurea

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1998.tb08272.x ◽

1998 ◽

Vol 853 (1 CARDIAC SARCO) ◽

pp. 240-250 ◽

Cited By ~ 16

Author(s):

ROBERT H. G. SCHWINGER ◽

BIRGIT BOLCK ◽

GOTZ MUNCH ◽

KLARA BRIXIUS ◽

JOCHEN MULLER-EHMSEN ◽

...

Keyword(s):

Protein Kinase ◽

Sarcoplasmic Reticulum ◽

Protein Kinase A ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Kinase A

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Negative role of cAMP‐dependent protein kinase A in RANTES‐mediated transcription of proinflammatory mediators through Raf

The FASEB Journal ◽

10.1096/fj.02-0962fje ◽

2003 ◽

Vol 17 (6) ◽

pp. 734-736 ◽

Cited By ~ 9

Author(s):

Ye Zhang ◽

Yi Luo ◽

Qiwei Zhai ◽

Liying Ma ◽

Martin E. Dorf

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Proinflammatory Mediators ◽

Dependent Protein ◽

Negative Role ◽

Kinase A

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Roles of the catalytic subunit of cAMP-dependent protein kinase A in virulence and development of the soilborne plant pathogen Verticillium dahliae

Fungal Genetics and Biology ◽

10.1016/j.fgb.2010.01.007 ◽

2010 ◽

Vol 47 (5) ◽

pp. 406-415 ◽

Cited By ~ 65

Author(s):

Aliki Tzima ◽

Epaminondas J. Paplomatas ◽

Payungsak Rauyaree ◽

Seogchan Kang

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Verticillium Dahliae ◽

Plant Pathogen ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Soilborne Plant Pathogen ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Kinase A

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Insights into the Phosphoryl-Transfer Mechanism of cAMP-Dependent Protein Kinase from Quantum Chemical Calculations and Molecular Dynamics Simulations

Journal of the American Chemical Society ◽

10.1021/ja037277u ◽

2004 ◽

Vol 126 (2) ◽

pp. 529-542 ◽

Cited By ~ 44

Author(s):

Natalia Díaz ◽

Martin J. Field

Keyword(s):

Molecular Dynamics ◽

Protein Kinase ◽

Molecular Dynamics Simulations ◽

Quantum Chemical Calculations ◽

Quantum Chemical ◽

Transfer Mechanism ◽

Phosphoryl Transfer ◽

Dependent Protein Kinase ◽

Dependent Protein ◽

Dynamics Simulations

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EFFECTS OF SEPSIS ON cAMP DEPENDENT PROTEIN KINASE A (PKA) ACTIVITY IN RAT LIVER

Shock ◽

10.1097/00024382-199506000-00154 ◽

1995 ◽

Vol 3 (6) ◽

pp. 44

Author(s):

K. Andrejko ◽

C. Deutschman

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Rat Liver ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Kinase A

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