Aromatic Interactions Are Not Required for Amyloid Fibril Formation by Islet Amyloid Polypeptide but Do Influence the Rate of Fibril Formation and Fibril Morphology†

Biochemistry ◽  
2007 ◽  
Vol 46 (11) ◽  
pp. 3255-3261 ◽  
Author(s):  
Peter Marek ◽  
Andisheh Abedini ◽  
BenBen Song ◽  
Mandakini Kanungo ◽  
Megan E. Johnson ◽  
...  
Keyword(s):  
Amyloid Fibril ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Islet Amyloid ◽  
Aromatic Interactions ◽  
Amyloid Fibril Formation ◽  
Fibril Morphology

scholarly journals Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.

1990 ◽  
Vol 87 (13) ◽  
pp. 5036-5040 ◽  
Author(s):  
P. Westermark ◽  
U. Engstrom ◽  
K. H. Johnson ◽  
G. T. Westermark ◽  
C. Betsholtz
Keyword(s):  
Amino Acid ◽  
Amyloid Fibril ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Amino Acid Residues ◽  
Islet Amyloid ◽  
Amyloid Fibril Formation

scholarly journals Does deamidation of islet amyloid polypeptide accelerate amyloid fibril formation?

2018 ◽  
Vol 54 (98) ◽  
pp. 13853-13856 ◽  
Author(s):  
Yuko P. Y. Lam ◽  
Christopher A. Wootton ◽  
Ian Hands-Portman ◽  
Juan Wei ◽  
Cookson K. C. Chiu ◽  
...  
Keyword(s):  
Amyloid Fibril ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Wild Type ◽  
Islet Amyloid ◽  
Amyloid Fibril Formation

Deamidation sites of hIAPP were determined and the amount of fibril formed in mutant hIAPPs was higher than in wild-type hIAPP.

Amyloid fibril formation by partially unfolded islet amyloid polypeptide (IAPP)

2006 ◽  
pp. 721-723
Author(s):  
Aphrodite Kapurniotu ◽  
Jürgen Bernhagen ◽  
Rakez Kayed ◽  
Norma Greenfield ◽  
Herwig Brunner ◽  
...  
Keyword(s):  
Amyloid Fibril ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Islet Amyloid ◽  
Amyloid Fibril Formation ◽  
Partially Unfolded
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