scholarly journals The Role of Protein Dynamics in Thymidylate Synthase Catalysis:  Variants of Conserved 2‘-Deoxyuridine 5‘-Monophosphate (dUMP)-Binding Tyr-261†,‡

Biochemistry ◽  
2006 ◽  
Vol 45 (24) ◽  
pp. 7415-7428 ◽  
Author(s):  
Zachary Newby ◽  
Tom T. Lee ◽  
Richard J. Morse ◽  
Yaoquan Liu ◽  
Lu Liu ◽  
...  
Keyword(s):  
Protein Dynamics ◽  
Thymidylate Synthase

scholarly journals Catalytic role of histidine 147 in Escherichia coli thymidylate synthase

1989 ◽  
Vol 264 (32) ◽  
pp. 19132-19137
Author(s):  
I K Dev ◽  
B B Yates ◽  
J Atashi ◽  
W S Dallas
Keyword(s):  
Escherichia Coli ◽  
Thymidylate Synthase ◽  
Catalytic Role

scholarly journals Role of Y94 in Proton and Hydride Transfers Catalyzed by Thymidylate Synthase†

Biochemistry ◽  
2007 ◽  
Vol 46 (49) ◽  
pp. 14188-14197 ◽  
Author(s):  
Baoyu Hong ◽  
Frank Maley ◽  
Amnon Kohen
Keyword(s):  
Thymidylate Synthase

scholarly journals 155 The role of solvent mobility in protein dynamics

2015 ◽  
Vol 33 (sup1) ◽  
pp. 100-101
Author(s):  
Qiong Yang ◽  
Peng Sang ◽  
Shu-Qun Liu
Keyword(s):  
Protein Dynamics ◽  
Role Of Solvent

468 POSTER The role of thymidine kinase and thymidylate synthase in the response of tumor cells to the suicide prodrug 2′-F-ara-deoxyuridine

2008 ◽  
Vol 6 (12) ◽  
pp. 150
Author(s):  
P. Phatak ◽  
C.M. Daniels ◽  
A.F. Shields ◽  
J.M. Collins ◽  
P.M. LoRusso ◽  
...  
Keyword(s):  
Thymidine Kinase ◽  
Tumor Cells ◽  
Thymidylate Synthase

Mechanisms of Acquired Resistance to Thymidylate Synthase Inhibitors: The Role of Enzyme Stability

1999 ◽  
Vol 56 (5) ◽  
pp. 1063-1070 ◽  
Author(s):  
Maria E. Kitchens ◽  
Antonia M. Forsthoefel ◽  
Karen W. Barbour ◽  
H. Trent Spencer ◽  
Franklin G. Berger
Keyword(s):  
Thymidylate Synthase ◽  
Enzyme Stability ◽  
Acquired Resistance ◽  
Thymidylate Synthase Inhibitors

Role of P53 Status on Sensitivity to Thymidylate Synthase Inhibitors and Induction of Apoptosis

2002 ◽  
pp. 433-437
Author(s):  
H. H. J. Backus ◽  
H. M. Pinedo ◽  
D. Wouters ◽  
M. C. Koudijs ◽  
C. G. Ferreira ◽  
...  
Keyword(s):  
Thymidylate Synthase ◽  
P53 Status ◽  
Induction Of Apoptosis ◽  
Thymidylate Synthase Inhibitors
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