Electrostatic Effects on the Stability of Discoidal High-Density Lipoproteins†

Biochemistry ◽  
2005 ◽  
Vol 44 (30) ◽  
pp. 10218-10226 ◽  
Author(s):  
Sangeeta Benjwal ◽  
Shobini Jayaraman ◽  
Olga Gursky
Keyword(s):  
High Density ◽  
High Density Lipoproteins ◽  
Electrostatic Effects ◽  
The Stability

scholarly journals Importance of Apolipoprotein A-I and A-II Composition in HDL and Its Potential for Studying COVID-19 and SARS-CoV-2

Medicines ◽  
2021 ◽  
Vol 8 (7) ◽  
pp. 38
Author(s):  
Kyung-Hyun Cho
Keyword(s):  
Antiviral Activity ◽  
High Density ◽  
High Density Lipoproteins ◽  
Potent Antiviral Activity ◽  
Apolipoprotein A ◽  
Putative Role

The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I or other apolipoproteins did not. However, there has been no report to elucidate the putative role of apoA-II in the antiviral activity of HDL.

Sign in / Sign up

Export Citation Format

Share Document