Asymmetric Distribution of Cooperativity in the Binding Cascade of Normal Human Hemoglobin. 1. Cooperative and Noncooperative Oxygen Binding in Zn-Substituted Hemoglobin†

Biochemistry ◽  
2005 ◽  
Vol 44 (36) ◽  
pp. 11925-11938 ◽  
Author(s):  
Jo M. Holt ◽  
Alexandra L. Klinger ◽  
Connie S. Yarian ◽  
Varsha Keelara ◽  
Gary K. Ackers
Keyword(s):  
Asymmetric Distribution ◽  
Oxygen Binding ◽  
Human Hemoglobin ◽  
Normal Human

Effect of Age on Oxygen-Binding in Normal Human Subjects

1976 ◽  
Vol 51 (2) ◽  
pp. 185-188
Author(s):  
P. M. Tweeddale ◽  
R. J. E. Leggett ◽  
D. C. Flenley
Keyword(s):  
Oxygen Saturation ◽  
Oxygen Tension ◽  
Inorganic Phosphate ◽  
Human Subjects ◽  
Oxygen Binding ◽  
Corpuscular Haemoglobin ◽  
Positive Correlation ◽  
Normal Human ◽  
Mean Corpuscular Haemoglobin ◽  
Effect Of Age

1. Oxygen-binding, plasma and intra-erythrocytic pH, and haemoglobin, 2,3-diphosphoglycerate and inorganic phosphate concentrations were measured in sixty-two healthy non-smokers aged between 18 and 89 years. 2. P50 (oxygen tension at 50% oxygen saturation) expressed at plasma pH 7·40 and Pco2 5·33 kPa showed a positive correlation with age. 3. This correlation of P50 with age was closer when P50 was expressed at a constant intra-erythrocytic pH 7·20. On average P50 at intra-erythrocytic pH 7·20 increased from 3·59 kPa at 20 years to 3·96 kPa at 90 years of age. 4. 2,3-Diphosphoglycerate, inorganic phosphate, haemoglobin and mean corpuscular haemoglobin concentrations did not correlate with P50 or with age.

Modification of human hemoglobin with methyl acyl phosphates derived from dicarboxylic acids. Systematic relationships between cross-linked structure and oxygen-binding properties

Biochemistry ◽  
1993 ◽  
Vol 32 (1) ◽  
pp. 215-223 ◽  
Author(s):  
Richard T. Jones ◽  
Charlotte G. Head ◽  
Thomas S. Fujita ◽  
Daniel T. B. Shih ◽  
Jolanta Wodzinska ◽  
...  
Keyword(s):  
Dicarboxylic Acids ◽  
Oxygen Binding ◽  
Human Hemoglobin ◽  
Binding Properties ◽  
Systematic Relationships

scholarly journals 3P086 Oxygen binding properties of recombinant human hemoglobin with heme rotational disorder

2005 ◽  
Vol 45 (supplement) ◽  
pp. S225
Author(s):  
Y. Aki-Jin ◽  
S. Nagatomo ◽  
Y. Yamamoto ◽  
M. Nagai ◽  
K. Imai
Keyword(s):  
Oxygen Binding ◽  
Human Hemoglobin ◽  
Binding Properties

Chlorpromazine induced aggregation of normal human hemoglobin. Electron microscopic evidence

1992 ◽  
Vol 44 (3) ◽  
pp. 209-217 ◽  
Author(s):  
Maitree Bhattacharyya ◽  
A.N. Ghosh ◽  
U. Chaudhuri ◽  
R.K. Poddar
Keyword(s):  
Human Hemoglobin ◽  
Electron Microscopic ◽  
Microscopic Evidence ◽  
Normal Human ◽  
Induced Aggregation

Oxygen binding and other physical properties of human hemoglobin made in yeast

1992 ◽  
Vol 5 (8) ◽  
pp. 807-810 ◽  
Author(s):  
K. Adachi ◽  
P. Konitzer ◽  
C.H. Lai ◽  
J. Kim ◽  
S. Surrey
Keyword(s):  
Physical Properties ◽  
Oxygen Binding ◽  
Human Hemoglobin ◽  
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