scholarly journals Recognition of Anionic Phospholipid Membranes by an Antihemostatic Protein from a Blood-Feeding Insect

Biochemistry ◽  
2004 ◽  
Vol 43 (22) ◽  
pp. 6987-6994 ◽  
Author(s):  
John F. Andersen ◽  
Nanda P. Gudderra ◽  
Ivo M. B. Francischetti ◽  
Jesus G. Valenzuela ◽  
José M. C. Ribeiro
Keyword(s):  
Blood Feeding ◽  
Phospholipid Membranes ◽  
Anionic Phospholipid ◽  
Anionic Phospholipid Membranes

β2-Glycoprotein I: Target antigen for ‘antiphospholipid’ antibodies. Immunological and molecular aspects

Lupus ◽  
1998 ◽  
Vol 7 (2_suppl) ◽  
pp. 5-9 ◽  
Author(s):  
Y Sheng ◽  
DA Kandiah ◽  
SA Krilis
Keyword(s):  
Antiphospholipid Syndrome ◽  
Antiphospholipid Antibodies ◽  
Fluid Phase ◽  
Target Antigen ◽  
Phospholipid Membranes ◽  
Anionic Phospholipid ◽  
Glycoprotein I ◽  
High Concentrations ◽  
Molecular Aspects ◽  
Anionic Phospholipid Membranes

It has become clear that β2-glycoprotein I (β2GPI) is the most common and best-characterised antigenic target for ‘antiphospholipid’ (aPL) autoantibodies. These antibodies preferentially bind β2GPI that has been immobilised on anionic phospholipid membranes or certain synthetic surfaces. These surfaces appear to act by increasing antigen density to allow binding of intrinsically low-affinity anti-β2GPI autoantibodies. Binding of β2GPI in fluid phase is weak and requires high concentrations of β2GPI. Our understanding of the pathophysiology of the ‘Antiphospholipid’ Syndrome (APS) has increased exponentially with the number of studies into the interactions of aPL antibodies and β2GPI.

scholarly journals Association of proacrosin with phospholipid membranes

1982 ◽  
Vol 201 (3) ◽  
pp. 657-660 ◽  
Author(s):  
J. William Straus ◽  
Kenneth L. Polakoski
Keyword(s):  
Electrostatic Charge ◽  
Phospholipid Membranes ◽  
Membrane Composition ◽  
Binding Assays ◽  
Anionic Phospholipid ◽  
Direct Binding ◽  
Anionic Phospholipid Membranes ◽  
Stimulation Of ◽  
Charge Interactions

Proacrosin, the zymogen precursor of acrosin, was shown to associate with anionic phospholipid membranes through apparent electrostatic charge interactions. This association was diminished by elevated cation concentrations and was dependent on membrane composition, as shown both by direct binding assays and by following the phospholipid stimulation of conversion of proacrosin into acrosin.

scholarly journals Effect of Antimicrobial Peptides from Australian Tree Frogs on Anionic Phospholipid Membranes

2009 ◽  
Vol 96 (3) ◽  
pp. 156a ◽  
Author(s):  
Frances Separovic ◽  
John D. Gehman ◽  
Tzong-Hsien Lee ◽  
John H. Bowie ◽  
Marie-Isabel Aguilar
Keyword(s):  
Antimicrobial Peptides ◽  
Phospholipid Membranes ◽  
Anionic Phospholipid ◽  
Tree Frogs ◽  
Anionic Phospholipid Membranes

Interaction of the GBV-C E2-derived peptide, P6-2VIR576, with anionic phospholipid membranes

2017 ◽  
Vol 532 ◽  
pp. 483-492 ◽  
Author(s):  
Alba Ortiz ◽  
Victoria Girona ◽  
Josefina Prat ◽  
M. Montserrat Muñoz-Juncosa ◽  
M. Asunción Alsina ◽  
...  
Keyword(s):  
Phospholipid Membranes ◽  
Anionic Phospholipid ◽  
Anionic Phospholipid Membranes

Kinetoplastid Membrane Protein-11 Induces Pores in Anionic Phospholipid Membranes: Effect of Cholesterol

Langmuir ◽  
2020 ◽  
Vol 36 (13) ◽  
pp. 3522-3530 ◽  
Author(s):  
Animesh Halder ◽  
Achinta Sannigrahi ◽  
Nayan De ◽  
Krishnananda Chattopadhyay ◽  
Sanat Karmakar
Keyword(s):  
Membrane Protein ◽  
Phospholipid Membranes ◽  
Anionic Phospholipid ◽  
Anionic Phospholipid Membranes

Effect of Antimicrobial Peptides from Australian Tree Frogs on Anionic Phospholipid Membranes†

Biochemistry ◽  
2008 ◽  
Vol 47 (33) ◽  
pp. 8557-8565 ◽  
Author(s):  
John D. Gehman ◽  
Fiona Luc ◽  
Kristopher Hall ◽  
Tzong-Hsien Lee ◽  
Martin P. Boland ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Phospholipid Membranes ◽  
Anionic Phospholipid ◽  
Tree Frogs ◽  
Anionic Phospholipid Membranes
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