Insulin Substrates 1 and 2 Are Corequired for Activation of Atypical Protein Kinase C and Cbl-Dependent Phosphatidylinositol 3-Kinase during Insulin Action in Immortalized Brown Adipocytes†

Atsushi Miura; Mini P. Sajan; Mary L. Standaert; Gautam Bandyopadhyay; C. Ronald Kahn; Robert V. Farese

doi:10.1021/bi049221y

Insulin Substrates 1 and 2 Are Corequired for Activation of Atypical Protein Kinase C and Cbl-Dependent Phosphatidylinositol 3-Kinase during Insulin Action in Immortalized Brown Adipocytes†

Biochemistry ◽

10.1021/bi049221y ◽

2004 ◽

Vol 43 (49) ◽

pp. 15503-15509 ◽

Cited By ~ 14

Author(s):

Atsushi Miura ◽

Mini P. Sajan ◽

Mary L. Standaert ◽

Gautam Bandyopadhyay ◽

C. Ronald Kahn ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Action ◽

Phosphatidylinositol 3 Kinase ◽

Atypical Protein Kinase C ◽

Brown Adipocytes ◽

Atypical Protein Kinase ◽

Kinase C ◽

Phosphatidylinositol 3

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Requirements for pYXXM Motifs in Cbl for Binding to the p85 Subunit of Phosphatidylinositol 3-Kinase and Crk, and Activation of Atypical Protein Kinase C and Glucose Transport during Insulin Action in 3T3/L1 Adipocytes†

Biochemistry ◽

10.1021/bi049222q ◽

2004 ◽

Vol 43 (49) ◽

pp. 15494-15502 ◽

Cited By ~ 12

Author(s):

Mary L. Standaert ◽

Mini P. Sajan ◽

Atsushi Miura ◽

Gautam Bandyopadhyay ◽

Robert V. Farese

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Glucose Transport ◽

Insulin Action ◽

Phosphatidylinositol 3 Kinase ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Phosphatidylinositol 3

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Phosphatidylinositol-3-kinase activation and atypical protein kinase C ζ phosphorylation characterize the DMSO signalling in erythroleukemia cells

Cellular Signalling ◽

10.1016/s0898-6568(00)00109-1 ◽

2000 ◽

Vol 12 (9-10) ◽

pp. 667-672 ◽

Cited By ~ 23

Author(s):

Amelia Cataldi ◽

Roberta Di Pietro ◽

Lucia Centurione ◽

Alfredo Grilli ◽

Giuseppina Cutroneo ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Atypical Protein Kinase C ◽

Kinase Activation ◽

Atypical Protein Kinase ◽

Kinase C ◽

Erythroleukemia Cells ◽

Phosphatidylinositol 3

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Cbl PYXXM Motifs Activate the P85 Subunit of Phosphatidylinositol 3-Kinase, Crk, Atypical Protein Kinase C, and Glucose Transport during Thiazolidinedione Action in 3T3/L1 and Human Adipocytes†

Biochemistry ◽

10.1021/bi034808i ◽

2003 ◽

Vol 42 (48) ◽

pp. 14335-14341 ◽

Cited By ~ 8

Author(s):

Atsushi Miura ◽

Mini P. Sajan ◽

Mary L. Standaert ◽

Gautam Bandyopadhyay ◽

Dawn M. Franklin ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Glucose Transport ◽

Human Adipocytes ◽

Phosphatidylinositol 3 Kinase ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Phosphatidylinositol 3

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Phosphatidylinositol-3-Kinase-Atypical Protein Kinase C Signaling Is Required for Wnt Attraction and Anterior-Posterior Axon Guidance

Journal of Neuroscience ◽

10.1523/jneurosci.0029-08.2008 ◽

2008 ◽

Vol 28 (13) ◽

pp. 3456-3467 ◽

Cited By ~ 65

Author(s):

A. M. Wolf ◽

A. I. Lyuksyutova ◽

A. G. Fenstermaker ◽

B. Shafer ◽

C. G. Lo ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Axon Guidance ◽

Phosphatidylinositol 3 Kinase ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Anterior Posterior ◽

Phosphatidylinositol 3

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Faculty Opinions recommendation of Atypical protein kinase C-zeta is essential for delayed phagocytosis of Helicobacter pylori.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004446.161957 ◽

2002 ◽

Author(s):

David Underhill

Keyword(s):

Helicobacter Pylori ◽

Protein Kinase C ◽

Protein Kinase ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Protein Kinase C Zeta

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Faculty Opinions recommendation of The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002435.25855 ◽

2001 ◽

Author(s):

Eamonn Maher

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Tumor Suppressor ◽

Tumor Suppressor Protein ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Von Hippel Lindau ◽

Kinase C

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Faculty Opinions recommendation of Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1089955.543122 ◽

2008 ◽

Author(s):

Mark Hargreaves

Keyword(s):

Skeletal Muscle ◽

Protein Kinase C ◽

Protein Kinase ◽

Human Skeletal Muscle ◽

Insulin Signalling ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Peptide Elongation

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Faculty Opinions recommendation of GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717988280.793472704 ◽

2013 ◽

Author(s):

David Wotton

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Basal Cell ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Basal Cell Carcinomas

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Faculty Opinions recommendation of Overexpression of atypical protein kinase C in HeLa cells facilitates macropinocytosis via Src activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718295550.793495175 ◽

2014 ◽

Author(s):

Vladimir Marshansky

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Hela Cells ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Src Activation

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Faculty Opinions recommendation of Loss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725347358.793505708 ◽

2015 ◽

Author(s):

Andrew Goryachev

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Interleukin 6 ◽

Mammary Cells ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Stat3 Signaling ◽

Kinase C

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