Inhibition of Human Telomerase Activity by an Engineered Zinc Finger Protein that Binds G-Quadruplexes†

Sachin D. Patel; Mark Isalan; Gérald Gavory; Sylvain Ladame; Yen Choo; Shankar Balasubramanian

doi:10.1021/bi048892t

Inhibition of Human Telomerase Activity by an Engineered Zinc Finger Protein that Binds G-Quadruplexes†

Biochemistry ◽

10.1021/bi048892t ◽

2004 ◽

Vol 43 (42) ◽

pp. 13452-13458 ◽

Cited By ~ 36

Author(s):

Sachin D. Patel ◽

Mark Isalan ◽

Gérald Gavory ◽

Sylvain Ladame ◽

Yen Choo ◽

...

Keyword(s):

Zinc Finger ◽

Zinc Finger Protein ◽

Telomerase Activity ◽

Finger Protein ◽

Human Telomerase

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Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTERT-mediated telomerase activity and telomere maintenance

Cell Death and Disease ◽

10.1038/cddis.2014.298 ◽

2014 ◽

Vol 5 (7) ◽

pp. e1334-e1334 ◽

Cited By ~ 16

Author(s):

B Gao ◽

K Li ◽

Y-Y Wei ◽

J Zhang ◽

J Li ◽

...

Keyword(s):

Oxidative Stress ◽

Zinc Finger ◽

Zinc Finger Protein ◽

Telomerase Activity ◽

Telomere Maintenance ◽

Premature Senescence ◽

Finger Protein ◽

Stress Induced Premature Senescence

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Faculty Opinions recommendation of Sequoia, a tramtrack-related zinc finger protein, functions as a pan-neural regulator for dendrite and axon morphogenesis in Drosophila.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1001579.24505 ◽

2001 ◽

Author(s):

Marta Llimargas

Keyword(s):

Zinc Finger ◽

Zinc Finger Protein ◽

Finger Protein ◽

Protein Functions

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Faculty Opinions recommendation of The zinc finger protein DIE-1 is required for late events during epithelial cell rearrangement in C. elegans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000339.5058 ◽

2001 ◽

Author(s):

Bruce Bowerman

Keyword(s):

Epithelial Cell ◽

Zinc Finger ◽

Zinc Finger Protein ◽

C Elegans ◽

Cell Rearrangement ◽

Finger Protein

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Faculty Opinions recommendation of Structure of a designed dimeric zinc finger protein bound to DNA.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000751.201374 ◽

2003 ◽

Author(s):

Barry Stoddard

Keyword(s):

Zinc Finger ◽

Zinc Finger Protein ◽

Finger Protein

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Faculty Opinions recommendation of The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1019065.216430 ◽

2004 ◽

Author(s):

James Briscoe

Keyword(s):

Zinc Finger ◽

Hedgehog Signaling ◽

Zinc Finger Protein ◽

Finger Protein

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Faculty Opinions recommendation of The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017913.206500 ◽

2004 ◽

Author(s):

Michael Lenhard

Keyword(s):

Zinc Finger ◽

Zinc Finger Protein ◽

Leaf Tissue ◽

Tissue Development ◽

Finger Protein

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Faculty Opinions recommendation of Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1060750.512673 ◽

2007 ◽

Author(s):

Vitaly Citovsky

Keyword(s):

Zinc Finger ◽

Biochemical Characterization ◽

Zinc Finger Protein ◽

Transcriptional Repressor ◽

Recognition Sequence ◽

Finger Protein ◽

Repressor Complex

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Faculty Opinions recommendation of Embryonic neural inducing factor churchill is not a DNA-binding zinc finger protein: solution structure reveals a solvent-exposed beta-sheet and zinc binuclear cluster.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1100091.556249 ◽

2008 ◽

Author(s):

Thomas Friedman

Keyword(s):

Dna Binding ◽

Zinc Finger ◽

Solution Structure ◽

Zinc Finger Protein ◽

Beta Sheet ◽

Protein Solution ◽

Binuclear Cluster ◽

Finger Protein ◽

Zinc Binuclear Cluster

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Faculty Opinions recommendation of Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8311972.8748072 ◽

2011 ◽

Author(s):

Joseph Bidwell

Keyword(s):

Zinc Finger ◽

Zinc Finger Protein ◽

Finger Protein

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Cloning and functional analysis of SCTF-1 encoding a C2H2-type zinc finger protein from soybean

Hereditas (Beijing) ◽

10.3724/sp.j.1005.2012.00749 ◽

2012 ◽

Vol 34 (6) ◽

pp. 749-756 ◽

Cited By ~ 1

Author(s):

Bing SONG ◽

Pi-Wu WANG ◽

Yong-Ping FU ◽

Xu-Hong FAN ◽

Hai-Feng XIA ◽

...

Keyword(s):

Functional Analysis ◽

Zinc Finger ◽

Zinc Finger Protein ◽

Finger Protein

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