Ca2+Transport by the Synaptosomal Plasma Membrane Ca2+-ATPase and the Effect of Thioridazine†

Biochemistry ◽  
2004 ◽  
Vol 43 (8) ◽  
pp. 2353-2358 ◽  
Author(s):  
Javier Palacios ◽  
M. Rosario Sepúlveda ◽  
Anthony G. Lee ◽  
Ana M. Mata
Keyword(s):  
Plasma Membrane ◽  
Synaptosomal Plasma Membrane

scholarly journals Interaction of bilirubin with the synaptosomal plasma membrane.

1988 ◽  
Vol 263 (3) ◽  
pp. 1255-1265
Author(s):  
J Vázquez ◽  
M García-Calvo ◽  
F Valdivieso ◽  
F Mayor ◽  
F Mayor
Keyword(s):  
Plasma Membrane ◽  
Synaptosomal Plasma Membrane

scholarly journals Calcium efflux and cycling across the synaptosomal plasma membrane

1985 ◽  
Vol 226 (1) ◽  
pp. 225-231 ◽  
Author(s):  
R Snelling ◽  
D Nicholls
Keyword(s):  
Plasma Membrane ◽  
Steady State ◽  
Potential Gradient ◽  
Electrochemical Potential ◽  
Electrochemical Gradient ◽  
Calcium Efflux ◽  
Normal Medium ◽  
Voltage Dependent ◽  
Synaptosomal Plasma Membrane ◽  
Ca2 Channels

Ca2+ efflux from intact synaptosomes is investigated. Net efflux can be induced by returning synaptosomes from media with elevated Ca2+ or high pH to a normal medium. Net Ca2+ efflux is accelerated when the Na+ electrochemical potential gradient is collapsed by veratridine plus ouabain. Under steady-state conditions at 30 degrees C, Ca2+ cycles across the plasma membrane at 0.38 nmol . min-1 . mg-1 of protein. Exchange is increased by 145% by veratridine plus ouabain, both influx and efflux being increased. Increased influx is probably due to activation of voltage-dependent Ca2+ channels, since it is abolished by verapamil. The results indicate that, at least under conditions of low Na+ electrochemical gradient, some pathway other than a Na+/Ca2+ exchange must operate in the plasma membrane to expel Ca2+.

Aminophospholipid Asymmetry in Murine Synaptosomal Plasma Membrane

1980 ◽  
Vol 34 (2) ◽  
pp. 269-277 ◽  
Author(s):  
Robert N. Fontaine ◽  
R. Adron Harris ◽  
Friedhelm Schroeder
Keyword(s):  
Plasma Membrane ◽  
Synaptosomal Plasma Membrane

Action and Binding of Calcium Channel Blockers on the Putative Calcium Channel of Synaptosomal Plasma Membrane from the Electric Organ of Narke japonica

1993 ◽  
Vol 707 (1 Molecular Bas) ◽  
pp. 410-412
Author(s):  
HIROSHI TOKUMARU ◽  
CHEN-YUEH WANG ◽  
NAOHIDE HIRASHIMA ◽  
TOMOHIRO O'HORI ◽  
HARUHIKO YAMAMOTO ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Electric Organ ◽  
Channel Blockers ◽  
Synaptosomal Plasma Membrane
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