Identification of Tyr504 as an Alternative Tyrosyl Radical Site in Human Prostaglandin H Synthase-2†

Biochemistry ◽  
2004 ◽  
Vol 43 (6) ◽  
pp. 1560-1568 ◽  
Author(s):  
Corina E. Rogge ◽  
Wen Liu ◽  
Gang Wu ◽  
Lee-Ho Wang ◽  
Richard J. Kulmacz ◽  
...  
Keyword(s):  
Tyrosyl Radical ◽  
Prostaglandin H Synthase ◽  
Radical Site ◽  
Prostaglandin H

scholarly journals Oxyferryl Heme and Not Tyrosyl Radical Is the Likely Culprit in Prostaglandin H Synthase-1 Peroxidase Inactivation†

Biochemistry ◽  
2007 ◽  
Vol 46 (2) ◽  
pp. 534-542 ◽  
Author(s):  
Gang Wu ◽  
Corina E. Rogge ◽  
Jinn-Shyan Wang ◽  
Richard J. Kulmacz ◽  
Graham Palmer ◽  
...  
Keyword(s):  
Tyrosyl Radical ◽  
Prostaglandin H Synthase ◽  
Prostaglandin H

scholarly journals Nitric Oxide Trapping of the Tyrosyl Radical of Prostaglandin H Synthase-2 Leads to Tyrosine Iminoxyl Radical and Nitrotyrosine Formation

1997 ◽  
Vol 272 (27) ◽  
pp. 17086-17090 ◽  
Author(s):  
Michael R. Gunther ◽  
Linda C. Hsi ◽  
John F. Curtis ◽  
James K. Gierse ◽  
Lawrence J. Marnett ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Tyrosyl Radical ◽  
Iminoxyl Radical ◽  
Prostaglandin H Synthase ◽  
Prostaglandin H

Rapid kinetics of tyrosyl radical formation and heme redox state changes in prostaglandin H synthase-1 and -2

1999 ◽  
Vol 59 (1-6) ◽  
pp. 120
Author(s):  
Ah-Lim Tsai ◽  
Gang Wu ◽  
Graham Palmer ◽  
Bijan Bambai ◽  
James A. Koehn ◽  
...  
Keyword(s):  
Redox State ◽  
Radical Formation ◽  
Tyrosyl Radical ◽  
Prostaglandin H Synthase ◽  
State Changes ◽  
Prostaglandin H ◽  
Rapid Kinetics ◽  
Kinetics Of

scholarly journals Cyclooxygenase Competitive Inhibitors Alter Tyrosyl Radical Dynamics in Prostaglandin H Synthase-2

Biochemistry ◽  
2009 ◽  
Vol 48 (50) ◽  
pp. 11902-11911 ◽  
Author(s):  
Gang Wu ◽  
Ah-Lim Tsai ◽  
Richard J. Kulmacz
Keyword(s):  
Tyrosyl Radical ◽  
Prostaglandin H Synthase ◽  
Competitive Inhibitors ◽  
Prostaglandin H

scholarly journals Rapid Kinetics of Tyrosyl Radical Formation and Heme Redox State Changes in Prostaglandin H Synthase-1 and -2

1999 ◽  
Vol 274 (31) ◽  
pp. 21695-21700 ◽  
Author(s):  
Ah-lim Tsai ◽  
Gang Wu ◽  
Graham Palmer ◽  
Bijan Bambai ◽  
James A. Koehn ◽  
...  
Keyword(s):  
Redox State ◽  
Radical Formation ◽  
Tyrosyl Radical ◽  
Prostaglandin H Synthase ◽  
State Changes ◽  
Prostaglandin H ◽  
Rapid Kinetics ◽  
Kinetics Of
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