DNA Damage and Cytotoxicity Induced by Minor Groove Binding Methyl Sulfonate Esters†

Biochemistry ◽  
2003 ◽  
Vol 42 (48) ◽  
pp. 14318-14327 ◽  
Author(s):  
Sridhar Varadarajan ◽  
Dharini Shah ◽  
Prasad Dande ◽  
Samuel Settles ◽  
Fa-xian Chen ◽  
...  
Keyword(s):  
Dna Damage ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Methyl Sulfonate

scholarly journals Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Raghib Ashraf ◽  
Hamidullah ◽  
Mohammad Hasanain ◽  
Praveen Pandey ◽  
Mayank Maheshwari ◽  
...  
Keyword(s):  
Dna Damage ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Post Translational Modifications

New orally active DNA minor groove binding small molecule CT-1 acts against breast cancer by targeting tumor DNA damage leading to p53-dependent apoptosis

2016 ◽  
Vol 56 (4) ◽  
pp. 1266-1280 ◽  
Author(s):  
Karan Singh Saini ◽  
Hamidullah ◽  
Raghib Ashraf ◽  
Dhanaraju Mandalapu ◽  
Sharmistha Das ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Damage ◽  
Small Molecule ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Dna Minor Groove ◽  
Orally Active ◽  
Tumor Dna

Thein VitroMethylation of DNA by a Minor Groove Binding Methyl Sulfonate Ester

1996 ◽  
Vol 9 (3) ◽  
pp. 563-567 ◽  
Author(s):  
Lance Encell ◽  
David E. G. Shuker ◽  
Peter G. Foiles ◽  
Barry Gold
Keyword(s):  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Methyl Sulfonate ◽  
A Minor ◽  
Sulfonate Ester

scholarly journals Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cells

Leukemia ◽  
2000 ◽  
Vol 14 (8) ◽  
pp. 1451-1459 ◽  
Author(s):  
L Tentori ◽  
P Vernole ◽  
PM Lacal ◽  
R Madaio ◽  
I Portarena ◽  
...  
Keyword(s):  
Mismatch Repair ◽  
Minor Groove ◽  
Leukemic Cells ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Dna Minor Groove ◽  
Methyl Sulfonate ◽  
Sulfonate Ester
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