Crystal Structure of F65A/Y131C-Methylimidazole Carbonic Anhydrase V Reveals Architectural Features of an Engineered Proton Shuttle†

Kevin M. Jude; S. Kirk Wright; Chingkuang Tu; David N. Silverman; Ronald E. Viola; David W. Christianson

doi:10.1021/bi015808q

Crystal Structure of F65A/Y131C-Methylimidazole Carbonic Anhydrase V Reveals Architectural Features of an Engineered Proton Shuttle†

Biochemistry ◽

10.1021/bi015808q ◽

2002 ◽

Vol 41 (8) ◽

pp. 2485-2491 ◽

Cited By ~ 66

Author(s):

Kevin M. Jude ◽

S. Kirk Wright ◽

Chingkuang Tu ◽

David N. Silverman ◽

Ronald E. Viola ◽

...

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Architectural Features

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An active site model for carbonic anhydrase. Synthesis and crystal structure of [η3-HB(3-Phpz)3]ZnBr

Polyhedron ◽

10.1016/0277-5387(94)00349-j ◽

1995 ◽

Vol 14 (8) ◽

pp. 1021-1023 ◽

Cited By ~ 5

Author(s):

Kewu Yang ◽

Yuanqi Yin ◽

Daosin Jin

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Active Site ◽

Synthesis And Crystal Structure ◽

Site Model ◽

Active Site Model

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Carbonic Anhydrase Inhibitors: Clash with Ala65 as a Means for Designing Inhibitors with Low Affinity for the Ubiquitous Isozyme II, Exemplified by the Crystal Structure of the Topiramate Sulfamide Analogue†

Journal of Medicinal Chemistry ◽

10.1021/jm060807n ◽

2006 ◽

Vol 49 (24) ◽

pp. 7024-7031 ◽

Cited By ~ 102

Author(s):

Jean-Yves Winum ◽

Claudia Temperini ◽

Khaled El Cheikh ◽

Alessio Innocenti ◽

Daniela Vullo ◽

...

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors

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Modification of a metal ligand in carbonic anhydrase: Crystal structure of His94 →Glu human isozyme II

FEBS Letters ◽

10.1016/0014-5793(94)00936-8 ◽

1994 ◽

Vol 352 (2) ◽

pp. 137-140 ◽

Cited By ~ 5

Author(s):

Yafeng Xue ◽

Bengt-Harald Jonsson ◽

Anders Liljas ◽

Sven Lindskog

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Metal Ligand

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Crystal Structure of the Complex between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole

Journal of Molecular Biology ◽

10.1006/jmbi.1993.1365 ◽

1993 ◽

Vol 232 (1) ◽

pp. 9-14 ◽

Cited By ~ 19

Author(s):

Stefano Mangani ◽

Anders Liljas

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Carbonic Anhydrase Ii ◽

Human Carbonic Anhydrase

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Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.02.068 ◽

2015 ◽

Vol 25 (9) ◽

pp. 2002-2006 ◽

Cited By ~ 43

Author(s):

Giuseppina De Simone ◽

Simona Maria Monti ◽

Vincenzo Alterio ◽

Martina Buonanno ◽

Viviana De Luca ◽

...

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Thermophilic Bacterium ◽

Carbonic Anhydrase Enzyme

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Novel Re(I) tricarbonyl coordination compounds based on 2-pyridyl-1,2,3-triazole derivatives bearing a 4-amino-substituted benzenesulfonamide arm: synthesis, crystal structure, computational studies and inhibitory activity against carbonic anhydrase I, II, and IX isoforms†

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2019.1585835 ◽

2019 ◽

Vol 34 (1) ◽

pp. 773-782 ◽

Cited By ~ 2

Author(s):

Yassine Aimene ◽

Romain Eychenne ◽

Sonia Mallet-Ladeira ◽

Nathalie Saffon ◽

Jean-Yves Winum ◽

...

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Inhibitory Activity ◽

Coordination Compounds ◽

Computational Studies ◽

Triazole Derivatives ◽

Carbonic Anhydrase I

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Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.161301298 ◽

2001 ◽

Vol 98 (17) ◽

pp. 9545-9550 ◽

Cited By ~ 171

Author(s):

D. A. Whittington ◽

A. Waheed ◽

B. Ulmasov ◽

G. N. Shah ◽

J. H. Grubb ◽

...

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Membrane Protein ◽

Tumor Cells ◽

Extracellular Domain ◽

Cancer Tumor ◽

Human Carbonic Anhydrase

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Crystal Structure of Carbonic Anhydrase II in Complex with an Activating Ligand: Implications in Neuronal Function

Molecular Neurobiology ◽

10.1007/s12035-017-0854-2 ◽

2018 ◽

Vol 55 (9) ◽

pp. 7431-7437 ◽

Cited By ~ 10

Author(s):

Avni Bhatt ◽

Utpal K. Mondal ◽

Claudiu T. Supuran ◽

Marc A. Ilies ◽

Robert McKenna

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Carbonic Anhydrase Ii ◽

Neuronal Function

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Crystal Structure of Human Erythrocyte Carbonic Anhydrase C. VI. The Three-dimensional Structure at High Resolution in Relation to Other Mammalian Carbonic Anhydrases

Cold Spring Harbor Symposia on Quantitative Biology ◽

10.1101/sqb.1972.036.01.030 ◽

1972 ◽

Vol 36 (0) ◽

pp. 221-231 ◽

Cited By ~ 57

Author(s):

K. K. Kannan ◽

A. Liljas ◽

I. Waara ◽

P.-C. Bergsten ◽

S. Lovgren ◽

...

Keyword(s):

Crystal Structure ◽

High Resolution ◽

Carbonic Anhydrase ◽

Human Erythrocyte ◽

Three Dimensional ◽

Dimensional Structure ◽

Carbonic Anhydrases ◽

Three Dimensional Structure ◽

Erythrocyte Carbonic Anhydrase

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ZINC COMPLEXES OF CARBONIC ANHYDRASE INHIBITORS. CRYSTAL STRUCTURE OF [Zn(5-AMINO-1,3,4-THIADIAZOLE- 2-SULFONAMIDATE)2(NH3)].H2O. CARBONIC ANHYDRASE INHIBITORY ACTIVITY

Main Group Metal Chemistry ◽

10.1515/mgmc.1998.21.5.279 ◽

1998 ◽

Vol 21 (5) ◽

Cited By ~ 8

Author(s):

P. Borja ◽

G. Alzuet ◽

J. Casanova ◽

J. Server-Carrio ◽

J. Borras ◽

...

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Inhibitory Activity ◽

Zinc Complexes ◽

Carbonic Anhydrase Inhibitors

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