Kinetics of binding of cyanide to hemin intercalated in micellar sodium lauryl sulfate

Biochemistry ◽  
1972 ◽  
Vol 11 (13) ◽  
pp. 2529-2534 ◽  
Author(s):  
Jon Simplicio
Keyword(s):  
Sodium Lauryl Sulfate ◽  
Lauryl Sulfate ◽  
Kinetics Of

scholarly journals THE INHIBITION OF HEMOLYSIS, AS STUDIED BY THE TECHNIQUE USED FOR INVESTIGATING PROGRESSIVE REACTIONS, AND BY A TECHNIQUE USING RADIOACTIVE HEMOLYSINS

1956 ◽  
Vol 40 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Eric Ponder ◽  
Ruth V. Ponder
Keyword(s):  
Sodium Lauryl Sulfate ◽  
Bulk Phase ◽  
Simple Explanation ◽  
Lauryl Sulfate ◽  
Red Cell ◽  
Cell Surfaces ◽  
Internal Phase ◽  
Before And After ◽  
Kinetics Of ◽  
Subsequent Addition

Inhibition of hemolysis by plasma has been studied in systems containing saponin, digitonin, and sodium lauryl sulfate, using the methods developed for the study of the kinetics of progressive reactions. The results are that the progressive nature of the hemolytic reaction in saponin systems becomes less when the inhibitor is added, that the addition of inhibitor to digitonin systems has no effect on the final result although the velocity of the progressive reaction is reduced, and that the effect of plasma in lauryl sulfate systems is intermediate between the effects in saponin systems and digitonin systems. A simple explanation is that the lysin is very strongly fixed, to form an internal phase, to the cell surfaces in digitonin systems, less strongly in laurate systems, and still less strongly in saponin systems. To answer the question as to whether, in a system in which some of the lysin forms as internal phase, the addition of an inhibitor results in a redistribution of the lysin between the internal phase and the bulk phase, sodium lauryl sulfate-S35 and sodium cetyl sulfate-S35 were prepared, and their distribution between the internal phase and the bulk phase was measured before and after the addition of plasma, the lysins being added to the cells either before or after the addition of the inhibitor. The results show that there is a large uptake of these lysins at the red cell surfaces when they are added first, and that the subsequent addition of plasma greatly reduces the quantity of lysin held in the internal phase. Further, if the inhibitor is added first and the lysin subsequently, the internal lysin phase is very incompletely formed. Serum albumin, used in place of plasma, gives essentially similar results.

Kinetics of sodium lauryl sulfate micelle dissociation by a light-scattering temperature-jump technique

1969 ◽  
Vol 73 (10) ◽  
pp. 3288-3289 ◽  
Author(s):  
B. C. Bennion ◽  
L. K. J. Tong ◽  
L. P. Holmes ◽  
E. M. Eyring
Keyword(s):  
Light Scattering ◽  
Sodium Lauryl Sulfate ◽  
Temperature Jump ◽  
Lauryl Sulfate ◽  
Kinetics Of

ASSESSMENT OF THE TOXICITY AND HAZARD OF SODIUM LAURYL SULFATE AT DIFFERENT EXPOSURE ROUTES

2020 ◽  
pp. 56-59
Author(s):  
M. V. Bidevkina ◽  
M. I. Golubeva ◽  
A. V. Limantsev ◽  
I. N. Razumnaya ◽  
T. N. Potapova ◽  
...  
Keyword(s):  
Sodium Lauryl Sulfate ◽  
Exposure Level ◽  
Hazardous Substance ◽  
Lauryl Sulfate ◽  
Upper Respiratory Tract ◽  
Mucous Membranes ◽  
Chloroprene Rubber ◽  
Upper Respiratory ◽  
Exposure Routes ◽  
Number Of Cells

Sodium lauryl sulfate is the most common surfactant used in the production of detergents, chloroprene rubber, plastics, artificial furs and in pharmaceutical industry. Sodium lauryl sulfate is a moderately hazardous substance when introduced into the stomach (DL50 for white mice and rats is in the range of 2086-2700 mg/kg), has a pronounced local irritant effect on the skin and mucous membranes of the eyes, has a skin-resorptive, sensitizing and pronounced cumulative effects. The threshold for acute inhalation action is set at 15,3 mg/m3 for changes in the function of the nervous system and irritating effects on the mucous membranes of the upper respiratory tract (an increase in the total number of cells in the nasal flushes).Recommended for approval tentative safe exposure level of sodium lauryl sulfate in the air of the working area is 0.2+ mg/m3 (aerosol).

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