Proton equilibriums and kinetics in the liver alcohol dehydrogenase reaction mechanism

J. D. Shore; H. Gutfreund; R. L. Brooks; D. Santiago; P. Santiago

doi:10.1021/bi00717a019

Proton equilibriums and kinetics in the liver alcohol dehydrogenase reaction mechanism

Biochemistry ◽

10.1021/bi00717a019 ◽

1974 ◽

Vol 13 (20) ◽

pp. 4185-4191 ◽

Cited By ~ 78

Author(s):

J. D. Shore ◽

H. Gutfreund ◽

R. L. Brooks ◽

D. Santiago ◽

P. Santiago

Keyword(s):

Reaction Mechanism ◽

Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction

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Kinetic evidence for a binary complex isomerization in the liver alcohol dehydrogenase reaction mechanism

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(71)90445-0 ◽

1971 ◽

Vol 147 (2) ◽

pp. 825-827 ◽

Cited By ~ 15

Author(s):

Joseph D. Shore ◽

Robert L. Brooks

Keyword(s):

Reaction Mechanism ◽

Alcohol Dehydrogenase ◽

Binary Complex ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction

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The Role of Conformational Changes in the Liver Alcohol Dehydrogenase Reaction Mechanism

Pyridine Nucleotide-Dependent Dehydrogenases ◽

10.1515/9783110853704-031 ◽

1977 ◽

pp. 416-425 ◽

Cited By ~ 4

Author(s):

Joseph D. Shore ◽

Herbert R. Halvorson ◽

Karen D. Lucast

Keyword(s):

Reaction Mechanism ◽

Alcohol Dehydrogenase ◽

Conformational Changes ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction

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Quenching of protein fluorescence by transient intermediates in the liver alcohol dehydrogenase reaction.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)41308-2 ◽

1975 ◽

Vol 250 (13) ◽

pp. 5276-5277

Author(s):

J D Shore ◽

H Gutfreund ◽

D Yates

Keyword(s):

Alcohol Dehydrogenase ◽

Protein Fluorescence ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction ◽

Transient Intermediates

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Transient kinetic studies of substrate inhibition in the horse liver alcohol dehydrogenase reaction

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(83)90502-7 ◽

1983 ◽

Vol 222 (1) ◽

pp. 59-66 ◽

Cited By ~ 14

Author(s):

Mitchell T. Kamlay ◽

Joseph D. Shore

Keyword(s):

Alcohol Dehydrogenase ◽

Substrate Inhibition ◽

Kinetic Studies ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction ◽

Horse Liver

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Substrate inhibition effects in the liver alcohol dehydrogenase reaction

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(66)90425-5 ◽

1966 ◽

Vol 117 (2) ◽

pp. 375-380 ◽

Cited By ~ 32

Author(s):

Joseph D. Shore ◽

Hugo Theorell

Keyword(s):

Alcohol Dehydrogenase ◽

Substrate Inhibition ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction

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Primary deuterium and tritium isotope effects upon V/K in the liver alcohol dehydrogenase reaction with ethanol

Biochemistry ◽

10.1021/bi00523a004 ◽

1981 ◽

Vol 20 (20) ◽

pp. 5662-5669 ◽

Cited By ~ 17

Author(s):

S. E. Damgaard

Keyword(s):

Alcohol Dehydrogenase ◽

Isotope Effects ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction

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Studies on the Mechanism of Enzyme-Catalyzed Oxidation Reduction Reactions. III. A Characterization of the Mechanism of the Liver Alcohol Dehydrogenase Reaction*

Biochemistry ◽

10.1021/bi00907a007 ◽

1962 ◽

Vol 1 (1) ◽

pp. 41-47 ◽

Cited By ~ 26

Author(s):

R. H. Baker

Keyword(s):

Alcohol Dehydrogenase ◽

Reduction Reactions ◽

Liver Alcohol Dehydrogenase ◽

Oxidation Reduction ◽

Dehydrogenase Reaction ◽

Catalyzed Oxidation

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Probes of a Role for Remote Binding Interactions on Hydrogen Tunneling in the Horse Liver Alcohol Dehydrogenase Reaction†

Biochemistry ◽

10.1021/bi9920331 ◽

2000 ◽

Vol 39 (6) ◽

pp. 1278-1284 ◽

Cited By ~ 18

Author(s):

Jodie K. Chin ◽

Judith P. Klinman

Keyword(s):

Alcohol Dehydrogenase ◽

Hydrogen Tunneling ◽

Horse Liver Alcohol Dehydrogenase ◽

Binding Interactions ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction ◽

Horse Liver

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Unmasking of hydrogen tunneling in the horse liver alcohol dehydrogenase reaction by site-directed mutagenesis

Biochemistry ◽

10.1021/bi00072a003 ◽

1993 ◽

Vol 32 (21) ◽

pp. 5503-5507 ◽

Cited By ~ 86

Author(s):

Brian J. Bahnson ◽

Doo Hong Park ◽

Keehyuk Kim ◽

Bryce V. Plapp ◽

Judith P. Klinman

Keyword(s):

Alcohol Dehydrogenase ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Hydrogen Tunneling ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction ◽

Horse Liver

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Deuterium isotope effects on initial rates of the liver alcohol dehydrogenase reaction. V

Biochemistry ◽

10.1021/bi00747a037 ◽

1973 ◽

Vol 12 (23) ◽

pp. 4802-4805 ◽

Cited By ~ 35

Author(s):

Karen Bush ◽

Vernon J. Shiner ◽

H. R. Mahler

Keyword(s):

Alcohol Dehydrogenase ◽

Isotope Effects ◽

Liver Alcohol Dehydrogenase ◽

Dehydrogenase Reaction ◽

Deuterium Isotope Effects

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