Light-induced free-radical reactions of nucleic acid constituents. Effect of sequence and base-base interactions on the reactivity of purines and pyrimidines in ribonucleotides

Biochemistry ◽  
1978 ◽  
Vol 17 (15) ◽  
pp. 3128-3133 ◽  
Author(s):  
Etta Livneh ◽  
Dov Elad ◽  
Joseph Sperling
Keyword(s):  
Free Radical ◽  
Nucleic Acid ◽  
Radical Reactions ◽  
Free Radical Reactions ◽  
Purines And Pyrimidines

The initial reaction mechanism and thermal sensitivity of a fluoropolymer-containing energetic molecular system: the coupling effect of interfacial interactions and free radical reactions

CrystEngComm ◽  
2021 ◽  
Vol 23 (16) ◽  
pp. 3006-3014
Author(s):  
Wen Qian
Keyword(s):  
Free Radical ◽  
Coupling Effect ◽  
Molecular System ◽  
Thermal Sensitivity ◽  
Radical Reactions ◽  
Initial Reaction ◽  
Interfacial Interactions ◽  
Free Radical Reactions ◽  
Molecular Systems ◽  
Reactive Molecular Dynamics

A strategy combining classic and reactive molecular dynamics is applied to find the coupling effect of interfacial interactions and free radical reactions during the initial thermal decomposition of fluoropolymer-containing molecular systems.

Further studies on free-radical pathology in the major central nervous system disorders: effect of very high doses of methylprednisolone on the functional outcome, morphology, and chemistry of experimental spinal cord impact injury

1982 ◽  
Vol 60 (11) ◽  
pp. 1415-1424 ◽  
Author(s):  
H. B. Demopoulos ◽  
E. S. Flamm ◽  
M. L. Seligman ◽  
D. D. Pietronigro ◽  
J. Tomasula ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Free Radical ◽  
Tissue Injury ◽  
Functional Restoration ◽  
Radical Reactions ◽  
Free Radical Reactions ◽  
Cord Injury

The hypothesis that pathologic free-radical reactions are initiated and catalyzed in the major central nervous system (CNS) disorders has been further supported by the current acute spinal cord injury work that has demonstrated the appearance of specific, cholesterol free-radical oxidation products. The significance of these products is suggested by the fact that: (i) they increase with time after injury; (ii) their production is curtailed with a steroidal antioxidant; (iii) high antioxidant doses of the steroidal antioxidant which curtail the development of free-radical product prevent tissue degeneration and permit functional restoration. The role of pathologic free-radical reactions is also inferred from the loss of ascorbic acid, a principal CNS antioxidant, and of extractable cholesterol. These losses are also prevented by the steroidal antioxidant. This model system is among others in the CNS which offer distinctive opportunities to study, in vivo, the onset and progression of membrane damaging free-radical reactions within well-defined parameters of time, extent of tissue injury, correlation with changes in membrane enzymes, and correlation with readily measurable in vivo functions.

Solvent Effects on the Oxidative Free Radical Reactions of 2-Amino-1,4-naphthoquinones.

ChemInform ◽  
2005 ◽  
Vol 36 (14) ◽  
Author(s):  
Chao-Ming Tseng ◽  
Yi-Lung Wu ◽  
Che-Ping Chuang
Keyword(s):  
Free Radical ◽  
Solvent Effects ◽  
Radical Reactions ◽  
Free Radical Reactions

Simulation of dioxygen free radical reactions

1993 ◽  
Vol 21 (3) ◽  
pp. 256S-256S ◽  
Author(s):  
PEDRO MONIZ-BARRETO ◽  
DAVID A. FELL
Keyword(s):  
Free Radical ◽  
Radical Reactions ◽  
Free Radical Reactions
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