Evidence that arginine-129 and arginine-145 are located within the heparin binding site of human antithrombin III

Biochemistry ◽  
1990 ◽  
Vol 29 (38) ◽  
pp. 8957-8962 ◽  
Author(s):  
Xiao Jian Sun ◽  
Jui Yoa Chang
Keyword(s):  
Binding Site ◽  
Antithrombin Iii ◽  
Heparin Binding ◽  
Heparin Binding Site

Pulmonary arterial thrombosis in a neonate with homozygous deficiency of antithrombin III: successful outcome following pulmonary thrombectomy and infusions of antithrombin III concentrate

2000 ◽  
Vol 10 (3) ◽  
pp. 275-278 ◽  
Author(s):  
K. Roman ◽  
E. Rosenthal ◽  
R. Razavi
Keyword(s):  
Binding Site ◽  
Arterial Thrombosis ◽  
Antithrombin Iii ◽  
Pulmonary Trunk ◽  
Successful Outcome ◽  
Heparin Binding ◽  
The Third ◽  
Heparin Binding Site ◽  
Surgical Thrombectomy ◽  
Pulmonary Arterial

AbstractWe report a newborn male who presented with severe central cyanosis on the third day of life. Partial thrombotic obstruction of the pulmonary trunk secondary to Antithrombin III (homozygous defect of heparin binding site) deficiency was subsequently diagnosed. Surgical thrombectomy, and infusions of Antithrombin III concentrate, led to a successful outcome. We postulate that intrauterine thrombosis occurred to give this unusual presentation.

scholarly journals A peptide model for the heparin binding site of antithrombin III

Biochemistry ◽  
1992 ◽  
Vol 31 (8) ◽  
pp. 2279-2285 ◽  
Author(s):  
Annemarie Coffman Lellouch ◽  
Peter T. Lansbury
Keyword(s):  
Binding Site ◽  
Antithrombin Iii ◽  
Heparin Binding ◽  
Heparin Binding Site

scholarly journals Important role of arginine 129 in heparin-binding site of antithrombin III. Identification of a novel mutation arginine 129 to glutamine.

1990 ◽  
Vol 265 (31) ◽  
pp. 18997-19001
Author(s):  
S Gandrille ◽  
M Aiach ◽  
D.A. Lane ◽  
D Vidaud ◽  
P Molho-Sabatier ◽  
...  
Keyword(s):  
Binding Site ◽  
Antithrombin Iii ◽  
Novel Mutation ◽  
Heparin Binding ◽  
Heparin Binding Site

scholarly journals Identification of the Antithrombin III Heparin Binding Site

1997 ◽  
Vol 272 (31) ◽  
pp. 19393-19400 ◽  
Author(s):  
Eva Ersdal-Badju ◽  
Aiqin Lu ◽  
Yancheng Zuo ◽  
Veronique Picard ◽  
Susan Clark Bock
Keyword(s):  
Binding Site ◽  
Antithrombin Iii ◽  
Heparin Binding ◽  
Heparin Binding Site
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