Dihydrofolate reductase from Escherichia coli: the kinetic mechanism with NADPH and reduced acetylpyridine adenine dinucleotide phosphate as substrates

Biochemistry ◽  
1988 ◽  
Vol 27 (15) ◽  
pp. 5493-5499 ◽  
Author(s):  
Stuart R. Stone ◽  
John F. Morrison
Keyword(s):  
Escherichia Coli ◽  
Dihydrofolate Reductase ◽  
Kinetic Mechanism

scholarly journals Role of aspartate 27 in the binding of methotrexate to dihydrofolate reductase from Escherichia coli.

1988 ◽  
Vol 263 (19) ◽  
pp. 9187-9198 ◽  
Author(s):  
J R Appleman ◽  
E E Howell ◽  
J Kraut ◽  
M Kühl ◽  
R L Blakley
Keyword(s):  
Escherichia Coli ◽  
Dihydrofolate Reductase

scholarly journals Methotrexate Binding to Dihydrofolate Reductase from a Methotrexate-resistant Strain of Escherichia coli

1973 ◽  
Vol 248 (18) ◽  
pp. 6375-6379
Author(s):  
Myra N. Williams ◽  
Martin Poe ◽  
Norma J. Greenfield ◽  
Jordan M. Hirshfield ◽  
Karst Hoogsteen
Keyword(s):  
Escherichia Coli ◽  
Dihydrofolate Reductase ◽  
Resistant Strain
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