NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite the cyclic analog of 2-deoxyribose

Biochemistry ◽  
1988 ◽  
Vol 27 (3) ◽  
pp. 924-931 ◽  
Author(s):  
Matthew W. Kalnik ◽  
Chien Neng Chang ◽  
Arthur P. Grollman ◽  
Dinshaw J. Patel
Keyword(s):  
Dna Duplexes ◽  
Nmr Studies ◽  
Cyclic Analog ◽  
Abasic Sites

NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite acyclic lesions

Biochemistry ◽  
1989 ◽  
Vol 28 (8) ◽  
pp. 3373-3383 ◽  
Author(s):  
Matthew W. Kalnik ◽  
Chien Neng Chang ◽  
Francis Johnson ◽  
Arthur P. Grollman ◽  
Dinshaw J. Patel
Keyword(s):  
Dna Duplexes ◽  
Nmr Studies ◽  
Abasic Sites

NMR studies of exocyclic 1,N2-propanodeoxyguanosine adducts (X) opposite purines in DNA duplexes: protonated X(syn).cntdot.A(anti) pairing (acidic pH) and X(syn).cntdot.G(anti) pairing (neutral pH) at the lesion site

Biochemistry ◽  
1989 ◽  
Vol 28 (13) ◽  
pp. 5647-5657 ◽  
Author(s):  
Michael Kouchakdjian ◽  
Edmund Marinelli ◽  
Xiaolian Gao ◽  
Francis Johnson ◽  
Arthur Grollman ◽  
...  
Keyword(s):  
Acidic Ph ◽  
Dna Duplexes ◽  
Lesion Site ◽  
Nmr Studies ◽  
Neutral Ph

scholarly journals How abasic sites impact hole transfer dynamics in GC-rich DNA sequences

2018 ◽  
Vol 20 (35) ◽  
pp. 23123-23131
Author(s):  
Marina Corbella ◽  
Alexander A. Voityuk ◽  
Carles Curutchet
Keyword(s):  
Dna Sequences ◽  
Dna Duplexes ◽  
Hole Transfer ◽  
Abasic Sites

Hole transfer dynamics through GC-rich DNA duplexes containing abasic sites is strongly modulated by the nature of the unpaired nucleobase.

scholarly journals NMR studies of DNA duplexes singly cross-linked by different synthetic linkers

1995 ◽  
Vol 23 (23) ◽  
pp. 4827-4835 ◽  
Author(s):  
Serge Altmann ◽  
Alexander M. Labhardt ◽  
Daniel Bur ◽  
Christain Lehmann ◽  
Willi Bannwarth ◽  
...  
Keyword(s):  
Dna Duplexes ◽  
Nmr Studies

NMR studies of an exocyclic 1,N2-propanodeoxyguanosine adduct (X) located opposite deoxyadenosine (A) in DNA duplexes at basic pH.: simultaneous partial intercalation of X and A between stacked bases

Biochemistry ◽  
1990 ◽  
Vol 29 (18) ◽  
pp. 4456-4465 ◽  
Author(s):  
Michael Kouchakdjian ◽  
Moises Eisenberg ◽  
David Live ◽  
Edmund Marinelli ◽  
Arthur P. Grollman ◽  
...  
Keyword(s):  
Dna Duplexes ◽  
Nmr Studies

NMR studies of the interaction of chromomycin A3 with small DNA duplexes I

Biochemistry ◽  
1987 ◽  
Vol 26 (4) ◽  
pp. 1058-1067 ◽  
Author(s):  
Max A. Keniry ◽  
Stephen C. Brown ◽  
Elisha Berman ◽  
Richard H. Shafer
Keyword(s):  
Dna Duplexes ◽  
Chromomycin A3 ◽  
Nmr Studies

NMR studies of DNA duplexes containing alpha-anomeric nucleotides and polarity reversals

1998 ◽  
Vol 76 (2-3) ◽  
pp. 403-410 ◽  
Author(s):  
James M Aramini ◽  
Markus W Germann
Keyword(s):  
Nucleic Acid ◽  
Dynamic Properties ◽  
Dna Duplexes ◽  
Nmr Studies ◽  
Complementary Dna ◽  
Nmr Techniques ◽  
Polarity Reversals ◽  
Alpha Beta ◽  
Shed Light ◽  
Medical Relevance

We present a summary of our research to date on a family of self-complementary DNA decamers containing single alpha-anomeric nucleotides flanked by 3'-3' and 5'-5' phosphodiester linkages from the perspective of the salient NMR techniques employed to shed light on the structural and dynamic properties of these sequences. Research into this class of synthetic alpha-/ beta-oligonucleotides containing mixed strand disposition may have medical relevance given their recently documented efficacy as antisense therapeutics.Key words: nucleic acid NMR, alpha anomeric, polarity reversals.

NMR studies of the interaction of chromomycin A3 with small DNA duplexes. Binding to GC-containing sequences

Biochemistry ◽  
1990 ◽  
Vol 29 (27) ◽  
pp. 6521-6534 ◽  
Author(s):  
Debra L. Banville ◽  
Max A. Keniry ◽  
Michal Kam ◽  
Richard H. Shafer
Keyword(s):  
Dna Duplexes ◽  
Chromomycin A3 ◽  
Nmr Studies
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