Protein structural changes accompanying formation of enzymic transition states: tryptophan environment in ground-state and transition-state analog complexes of adenosine deaminase

Linda C. Kurz; Derek LaZard; Carl Frieden

doi:10.1021/bi00327a011

Protein structural changes accompanying formation of enzymic transition states: tryptophan environment in ground-state and transition-state analog complexes of adenosine deaminase

Biochemistry ◽

10.1021/bi00327a011 ◽

1985 ◽

Vol 24 (6) ◽

pp. 1342-1346 ◽

Cited By ~ 26

Author(s):

Linda C. Kurz ◽

Derek LaZard ◽

Carl Frieden

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Ground State ◽

Structural Changes ◽

Transition States ◽

Transition State Analog

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Adenosine deaminase and adenylate deaminase: comparative kinetic studies with transition state and ground state analog inhibitors

Biochemistry ◽

10.1021/bi00564a024 ◽

1980 ◽

Vol 19 (23) ◽

pp. 5303-5309 ◽

Cited By ~ 94

Author(s):

Carl Frieden ◽

Linda C. Kurz ◽

Helen R. Gilbert

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Ground State ◽

Kinetic Studies ◽

Adenylate Deaminase

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Erratum: Atomic Structure of Adenosine Deaminase Complexed with a Transition-State Analog: Understanding Catalysis and Immunodeficiency Mutations

Science ◽

10.1126/science.253.5016.119.b ◽

1991 ◽

Vol 253 (5016) ◽

pp. 119-119

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Atomic Structure ◽

Transition State Analog

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ENZYMATIC TRANSITION STATES AND TRANSITION STATE ANALOG DESIGN

Annual Review of Biochemistry ◽

10.1146/annurev.biochem.67.1.693 ◽

1998 ◽

Vol 67 (1) ◽

pp. 693-720 ◽

Cited By ~ 171

Author(s):

Vern L. Schramm

Keyword(s):

Transition State ◽

Transition States ◽

Analog Design ◽

Transition State Analog

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Adenosine deaminase: viscosity studies and the mechanism of binding of substrate and of ground- and transition-state analog inhibitors

Biochemistry ◽

10.1021/bi00385a012 ◽

1987 ◽

Vol 26 (11) ◽

pp. 3027-3032 ◽

Cited By ~ 42

Author(s):

Linda C. Kurz ◽

Emma Weitkamp ◽

Carl Frieden

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Transition State Analog

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Comparison of vibrational frequencies of critical bonds in ground-state complexes and in a vanadate-based transition-state analog complex of muscle phosphoglucomutase. Mechanistic implications

Biochemistry ◽

10.1021/bi00211a006 ◽

1993 ◽

Vol 32 (48) ◽

pp. 12984-12992 ◽

Cited By ~ 10

Author(s):

Hua Deng ◽

William J. Ray ◽

John W. Burgner ◽

Robert Callender

Keyword(s):

Transition State ◽

Ground State ◽

Vibrational Frequencies ◽

Transition State Analog

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Binding Thermodynamics of the Transition State Analogue Coformycin and of the Ground State Analogue 1-Deazaadenosine to Bovine Adenosine Deaminase

Journal of Enzyme Inhibition ◽

10.1080/14756360109162370 ◽

2001 ◽

Vol 16 (3) ◽

pp. 217-232 ◽

Cited By ~ 5

Author(s):

Christian Castro ◽

B. Mark Britt

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Ground State ◽

Binding Thermodynamics ◽

Transition State Analogue

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Potential transition state analog for adenosine deaminase

Journal of the American Chemical Society ◽

10.1021/ja00718a056 ◽

1970 ◽

Vol 92 (15) ◽

pp. 4751-4752 ◽

Cited By ~ 80

Author(s):

Ben. Evans ◽

Richard. Wolfenden

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Transition State Analog

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Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations

Science ◽

10.1126/science.1925539 ◽

1991 ◽

Vol 252 (5010) ◽

pp. 1278-1284 ◽

Cited By ~ 305

Author(s):

D. Wilson ◽

F. Rudolph ◽

F. Quiocho

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Atomic Structure ◽

Transition State Analog

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Adenosine deaminase: solvent isotope and pH effects on the binding of transition-state and ground-state analog inhibitors

Biochemistry ◽

10.1021/bi00271a023 ◽

1983 ◽

Vol 22 (2) ◽

pp. 382-389 ◽

Cited By ~ 34

Author(s):

Linda C. Kurz ◽

Carl Frieden

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Ground State ◽

Ph Effects ◽

Solvent Isotope

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The absolute stereochemistry of nebularine-methanol photoadduct. A potential transition-state analog of adenosine deaminase.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.31.3104 ◽

1983 ◽

Vol 31 (9) ◽

pp. 3104-3112 ◽

Cited By ~ 11

Author(s):

MASAMI SHIMAZAKI ◽

HIKARU NAKAMURA ◽

YOICHI IITAKA ◽

MASAJI OHNO

Keyword(s):

Transition State ◽

Adenosine Deaminase ◽

Transition State Analog ◽

The Absolute ◽

Absolute Stereochemistry

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