Covalent thrombin-.alpha.2-macroglobulin complexes. Evidence for bivalent crosslinking of inhibitor chains by a single enzyme molecule

Biochemistry ◽  
1984 ◽  
Vol 23 (12) ◽  
pp. 2807-2811 ◽  
Author(s):  
Dalton Wang ◽  
Anna I. Yuan ◽  
Richard D. Feinman
Keyword(s):  
Enzyme Molecule ◽  
Single Enzyme

scholarly journals Detection of a single enzyme molecule based on a solid-state nanopore sensor

2016 ◽  
Vol 27 (15) ◽  
pp. 155502 ◽  
Author(s):  
ShengWei Tan ◽  
DeJian Gu ◽  
Hang Liu ◽  
QuanJun Liu
Keyword(s):  
Solid State ◽  
Enzyme Molecule ◽  
Single Enzyme

scholarly journals Single-molecule enzymology: What can it tell us?

2003 ◽  
Vol 25 (4) ◽  
pp. 24-27 ◽  
Author(s):  
Clive R. Bagshaw
Keyword(s):  
Enzyme Activity ◽  
Single Molecule ◽  
Enzyme Molecule ◽  
Basic Principles ◽  
Single Enzyme ◽  
Single Molecule Enzymology

In the last decade, several methods have been developed to measure enzyme activity at the level of a single enzyme molecule. This represents a considerable technical feat, but what does it allow us to learn about enzymes? Here, the basic principles are reviewed to show that new forms of heterogeneity in activity may be revealed and evidence gained for rare states that would otherwise be swamped in bulk assays.

scholarly journals Linear and Gaussian Analysis of a Single Enzyme Molecule by LC–MS

2020 ◽  
Vol 32 (1) ◽  
pp. 301-306
Author(s):  
Nan Cheng ◽  
Zhuo Zhen Chen ◽  
Angelique Florentinus-Mefailoski ◽  
Ming Miao ◽  
John G Marshall
Keyword(s):  
Enzyme Molecule ◽  
Gaussian Analysis ◽  
Single Enzyme

The Chemistry of a Single Enzyme Molecule

2003 ◽  
pp. 293-301 ◽  
Author(s):  
Robert Polakowski ◽  
Michael Eggertson ◽  
Douglas B. Craig ◽  
Norman J. Dovichi
Keyword(s):  
Enzyme Molecule ◽  
Single Enzyme

Peer Reviewed: Life and Death of a Single Enzyme Molecule

1998 ◽  
Vol 70 (1) ◽  
pp. 39A-43A ◽  
Author(s):  
Douglas B. Craig ◽  
Edgar Arriaga ◽  
Jerome C. Y. Wong ◽  
Hui Lu ◽  
and Norman J. Dovichi
Keyword(s):  
Enzyme Molecule ◽  
Life And Death ◽  
Single Enzyme

scholarly journals Collision-based Electrochemistry for Investigation of Direct Electron Transfer of a Single Enzyme Molecule

2017 ◽  
Vol 27 ◽  
pp. 238-239
Author(s):  
Alina N. Sekretaryova ◽  
Mikhail Yu. Vagin ◽  
Anthony P.F. Turner ◽  
Mats Eriksson
Keyword(s):  
Electron Transfer ◽  
Direct Electron Transfer ◽  
Enzyme Molecule ◽  
Single Enzyme

Toward Single Enzyme Molecule Electrochemistry

ACS Nano ◽  
2008 ◽  
Vol 2 (12) ◽  
pp. 2437-2440 ◽  
Author(s):  
Allen J. Bard
Keyword(s):  
Enzyme Molecule ◽  
Single Enzyme

Toward Single-Enzyme Molecule Electrochemistry: [NiFe]-Hydrogenase Protein Film Voltammetry at Nanoelectrodes

ACS Nano ◽  
2008 ◽  
Vol 2 (12) ◽  
pp. 2497-2504 ◽  
Author(s):  
Freek J. M. Hoeben ◽  
F. Stefan Meijer ◽  
Cees Dekker ◽  
Simon P. J. Albracht ◽  
Hendrik A. Heering ◽  
...  
Keyword(s):  
Enzyme Molecule ◽  
Protein Film ◽  
Protein Film Voltammetry ◽  
Single Enzyme
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