Guanine-1,N6-Ethenoadenine Base Pairs in the Crystal Structure of d(CGCGAATT(.epsilon.dA)GCG)

Biochemistry ◽  
1994 ◽  
Vol 33 (16) ◽  
pp. 4755-4761 ◽  
Author(s):  
Gordon A. Leonard ◽  
Katherine E. McAuley-Hecht ◽  
Neil J. Gibson ◽  
Tom Brown ◽  
William P. Watson ◽  
...  
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1989 ◽  
Vol 17 (1) ◽  
pp. 55-72 ◽  
Author(s):  
W.B.T. Cruse ◽  
J. Aymani ◽  
Olga Kennard ◽  
Tom Brown ◽  
Audrey G.C. Jack ◽  
...  
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1990 ◽  
Vol 9 (3) ◽  
pp. 467-469 ◽  
Author(s):  
L. Van Meervelt ◽  
M. H. Moore ◽  
P. Kong Thoo Lin ◽  
D. M. Brown ◽  
O. Kennard

2017 ◽  
Vol 23 (9) ◽  
pp. 2103-2108 ◽  
Author(s):  
Angel Terrón ◽  
Blas Moreno-Vachiano ◽  
Antonio Bauzá ◽  
Angel García-Raso ◽  
Juan Jesús Fiol ◽  
...  

Author(s):  
Selvam Karthik ◽  
Arunachalam Thirugnanasambandam ◽  
Pradeep Kumar Mandal ◽  
Namasivayam Gautham

The X-ray crystal structure of the DNA tetradecamer sequence d(CCGGGGTACCCCGG)2is reported at 1.4 Å resolution in the tetragonal space groupP41212. The sequence was designed to fold as a four-way junction. However, it forms an A-type double helix in the presence of barium chloride. The metal ion could not be identified in the electron-density map. The crystallographic asymmetric unit consists of one A-type double helix with 12 base pairs per turn, in contrast to 11 base pairs per turn for canonical A-DNA. A large number of solvent molecules have been identified in both the grooves of the duplex and around the backbone phosphate groups.


Author(s):  
Hristina I. Sbirkova-Dimitrova ◽  
Boris Shivachev

The structure of 4′,6-diamidine-2-phenylindole (DAPI) bound to the synthetic B-DNA oligonucleotide d(CGTGAATTCACG) has been solved in space groupP212121by single-crystal X-ray diffraction at a resolution of 2.2 Å. The structure is nearly isomorphous to that of the previously reported crystal structure of the oligonucleotide d(CGTGAATTCACG) alone. The adjustments in crystal packing between the native DNA molecule and the DNA–DAPI complex are described. DAPI lies in the narrow minor groove near the centre of the B-DNA fragment, positioned over the A–T base pairs. It is bound to the DNA by hydrogen-bonding and van der Waals interactions. Comparison of the two structures (with and without ligand) shows that DAPI inserts into the minor groove, displacing the ordered spine waters. Indeed, as DAPI is hydrophobic it confers this behaviour on the DNA and thus restricts the presence of water molecules.


2017 ◽  
Vol 53 (86) ◽  
pp. 11747-11750 ◽  
Author(s):  
Jiro Kondo ◽  
Toru Sugawara ◽  
Hisao Saneyoshi ◽  
Akira Ono

The crystal structures of 4-thiothymine–2AgI–4-thiothymine base pairs in B-form DNA duplexes have been solved.


2000 ◽  
Vol 299 (1) ◽  
pp. 113-122 ◽  
Author(s):  
Ke Shi ◽  
Roopa Biswas ◽  
Shome Nath Mitra ◽  
Muttaiya Sundaralingam
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2003 ◽  
Vol 3 (1) ◽  
pp. 225-226 ◽  
Author(s):  
R. Utsunomiya ◽  
P.K.R. Kumar ◽  
Z. Fujimoto ◽  
H. Mizuno
Keyword(s):  

2015 ◽  
Vol 127 (45) ◽  
pp. 13521-13524 ◽  
Author(s):  
Jiro Kondo ◽  
Yoshinari Tada ◽  
Takenori Dairaku ◽  
Hisao Saneyoshi ◽  
Itaru Okamoto ◽  
...  

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