Determination of the Redox Properties of Human NADPH-Cytochrome P450 Reductase†

Andrew W. Munro; Michael A. Noble; Laura Robledo; Simon N. Daff; Stephen K. Chapman

doi:10.1021/bi001718u

Determination of the Redox Properties of Human NADPH-Cytochrome P450 Reductase†

Biochemistry ◽

10.1021/bi001718u ◽

2001 ◽

Vol 40 (7) ◽

pp. 1956-1963 ◽

Cited By ~ 106

Author(s):

Andrew W. Munro ◽

Michael A. Noble ◽

Laura Robledo ◽

Simon N. Daff ◽

Stephen K. Chapman

Keyword(s):

Cytochrome P450 ◽

Redox Properties ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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A novel microplate-based HPLC-fluorescence assay for determination of NADPH-cytochrome P450 reductase activity

Biomedical Chromatography ◽

10.1002/bmc.1747 ◽

2011 ◽

Vol 26 (9) ◽

pp. 1062-1065 ◽

Cited By ~ 2

Author(s):

Tomas Erban ◽

Palmiro Poltronieri ◽

Jitka Stara

Keyword(s):

Cytochrome P450 ◽

Reductase Activity ◽

Fluorescence Assay ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Isolation of cytochrome P450 from hepatopancreas microsomes of the spiny lobster, Panulirus argus, and determination of catalytic activity with NADPH cytochrome P450 reductase from vertebrate liver

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(90)90080-i ◽

1990 ◽

Vol 282 (1) ◽

pp. 8-17 ◽

Cited By ~ 25

Author(s):

Margaret O. James

Keyword(s):

Cytochrome P450 ◽

Catalytic Activity ◽

Spiny Lobster ◽

Panulirus Argus ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

Nadph Cytochrome P450 Reductase

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The cytochrome P450 2B4-NADPH cytochrome P450 reductase electron transfer complex is not formed by charge-pairing.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42093-5 ◽

1992 ◽

Vol 267 (21) ◽

pp. 14669-14676

Author(s):

A.I. Voznesensky ◽

J.B. Schenkman

Keyword(s):

Electron Transfer ◽

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Nadph Cytochrome P450 Reductase ◽

Electron Transfer Complex

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Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase. Implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834fcf4f ◽

2012 ◽

Vol 23 (4) ◽

pp. 393-405 ◽

Cited By ~ 5

Author(s):

Dorota Kostrzewa-Nowak ◽

Bohdan Bieg ◽

Mark J.I. Paine ◽

C. Roland Wolf ◽

Jolanta Tarasiuk

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Structural Factors ◽

Cytochrome P450 Reductase ◽

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anthraquinone Derivatives ◽

Nadph Cytochrome P450 Reductase

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Organization of NADPH-Cytochrome P450 Reductase and CYP1A2 in the Endoplasmic Reticulum—Microdomain Localization Affects Monooxygenase Function

Molecular Pharmacology ◽

10.1124/mol.110.068817 ◽

2010 ◽

Vol 79 (3) ◽

pp. 549-557 ◽

Cited By ~ 24

Author(s):

Lauren Brignac-Huber ◽

James R. Reed ◽

Wayne L. Backes

Keyword(s):

Endoplasmic Reticulum ◽

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Role of the prosthetic groups of NADPH-cytochrome P450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxide anion production

Redox Report ◽

10.1080/13510002.1996.11747070 ◽

1996 ◽

Vol 2 (5) ◽

pp. 339-344

Author(s):

Y. Ohta ◽

R. Shinohara ◽

I. Ishiguro

Keyword(s):

Cytochrome P450 ◽

Superoxide Anion ◽

Cytochrome P450 Reductase ◽

Superoxide Anion Production ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anion Production ◽

Nadph Cytochrome P450 Reductase ◽

Prosthetic Groups

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Reduction of cytochrome b5 by NADPH–cytochrome P450 reductase

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2005.06.019 ◽

2005 ◽

Vol 440 (2) ◽

pp. 204-211 ◽

Cited By ~ 56

Author(s):

F. Peter Guengerich

Keyword(s):

Cytochrome P450 ◽

Cytochrome B5 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2010.08.072 ◽

2010 ◽

Vol 400 (3) ◽

pp. 374-378 ◽

Cited By ~ 26

Author(s):

Amit V. Pandey ◽

Christa E. Flück ◽

Primus E. Mullis

Keyword(s):

Cytochrome P450 ◽

Heme Oxygenase ◽

Heme Oxygenase 1 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Membrane Topology of NADPH–Cytochrome P450 Reductase on the Endoplasmic Reticulum

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1997.0553 ◽

1998 ◽

Vol 351 (2) ◽

pp. 175-179 ◽

Cited By ~ 22

Author(s):

Yuichiro Kida ◽

Satoru Ohgiya ◽

Katsuyoshi Mihara ◽

Masao Sakaguchi

Keyword(s):

Endoplasmic Reticulum ◽

Cytochrome P450 ◽

Membrane Topology ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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