Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives

Biochemistry ◽  
1992 ◽  
Vol 31 (48) ◽  
pp. 12069-12075 ◽  
Author(s):  
Yoshinori Yamashita ◽  
Noboru Fujii ◽  
Chikara Murakata ◽  
Tadashi Ashizawa ◽  
Masami Okabe ◽  
...  
Keyword(s):  
Dna Cleavage ◽  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase

Drug-induced Stabilization of Covalent DNA Topoisomerase I-DNA Intermediates: DNA Cleavage Assays

2003 ◽  
pp. 291-302
Author(s):  
Paola Fiorani ◽  
Christine L. Hann ◽  
Piero Benedetti ◽  
Mary-Ann Bjornsti
Keyword(s):  
Dna Cleavage ◽  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Drug Induced ◽  
Dna Topoisomerase

scholarly journals The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts

2008 ◽  
Vol 36 (12) ◽  
pp. 4128-4136 ◽  
Author(s):  
T. S. Dexheimer ◽  
A. Kozekova ◽  
C. J. Rizzo ◽  
M. P. Stone ◽  
Y. Pommier
Keyword(s):  
Dna Adducts ◽  
Dna Cleavage ◽  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase

Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus

Biochemistry ◽  
1991 ◽  
Vol 30 (24) ◽  
pp. 5838-5845 ◽  
Author(s):  
Yoshinori Yamashita ◽  
Shozou Kawada ◽  
Noboru Fujii ◽  
Hirofumi Nakano
Keyword(s):  
Dna Cleavage ◽  
Topoisomerase I ◽  
Antitumor Agent ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase

Characterization of DNA topoisomerase I from Mycobacterium tuberculosis: DNA cleavage and religation properties and inhibition of its activity

2012 ◽  
Vol 528 (2) ◽  
pp. 197-203 ◽  
Author(s):  
Adwait Anand Godbole ◽  
Majety Naga Leelaram ◽  
Anuradha Gopal Bhat ◽  
Paras Jain ◽  
Valakunja Nagaraja
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Dna Cleavage ◽  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase
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