Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional implications

Biochemistry ◽  
1992 ◽  
Vol 31 (34) ◽  
pp. 7756-7764 ◽  
Author(s):  
Francois Bontems ◽  
Bernard Gilquin ◽  
Christian Roumestand ◽  
Andre Menez ◽  
Flavio Toma
Keyword(s):  
Side Chain ◽  
Refined Model ◽  
Functional Implications ◽  
Chain Organization

Reply to the ‘Comment on “Relating side chain organization of PNIPAm with its conformation in aqueous methanol”’ by N. van der Vegt and F. Rodriguez-Ropero, Soft Matter, 2017, 13, DOI: 10.1039/C6SM02139E

Soft Matter ◽  
2017 ◽  
Vol 13 (12) ◽  
pp. 2292-2294 ◽  
Author(s):  
Debashish Mukherji ◽  
Manfred Wagner ◽  
Mark D. Watson ◽  
Svenja Winzen ◽  
Tiago E. de Oliveira ◽  
...  
Keyword(s):  
Soft Matter ◽  
Recent Article ◽  
Side Chain ◽  
Aqueous Methanol ◽  
Chain Organization

We provide a reply to comments by N. van der Vegt and F. Rodriguez-Ropero on our recent article in Soft Matter.

Reply to the ‘Comment on “Relating side chain organization of PNIPAm with its conformation in aqueous methanol”’ by A. Pica and G. Graziano, Soft Matter, 2017, 13, DOI: 10.1039/C7SM01065F

Soft Matter ◽  
2017 ◽  
Vol 13 (42) ◽  
pp. 7701-7703 ◽  
Author(s):  
Debashish Mukherji ◽  
Manfred Wagner ◽  
Mark D. Watson ◽  
Svenja Winzen ◽  
Tiago E. de Oliveira ◽  
...  
Keyword(s):  
Soft Matter ◽  
Side Chain ◽  
Aqueous Methanol ◽  
Chain Organization

We address on scientific grounds issues raised by a comment on our article in Soft Matter, 2016, 12, 7995, showing why requests to reinterpret our data do not hold.

Influence of glycidylmethacrylate functional groups attached to gelatin on the formation and properties of hydrogels

2015 ◽  
Vol 1718 ◽  
pp. 103-108 ◽  
Author(s):  
Candy Löwenberg ◽  
Konstanze K. Julich-Gruner ◽  
Axel T. Neffe ◽  
Andreas Lendlein
Keyword(s):  
Mechanical Properties ◽  
Glycidyl Methacrylate ◽  
Triple Helix ◽  
Polymer Concentration ◽  
Polymer Networks ◽  
Side Chain ◽  
Metathesis Reaction ◽  
Gelatin Films ◽  
Order Of Magnitude ◽  
Chain Organization

ABSTRACTGelatin functionalized with glycidyl methacrylate (GMA) has been shown to allow crosslinking by photopolymerization and metathesis reaction. However, side chain functionalization of gelatin might reduce triple helicalization, which influences mechanical properties of gelatin-based polymer networks. Here, the influence of glycidylmethycrylation of gelatin on the chain organization, swelling, and mechanical properties is investigated by comparing among each other physical gels prepared from GMA-gelatin solutions of different concentrations (5-20 wt.-%) by drying and rehydration. An increase of GMA-gelatin concentration from 5 wt.-% to 20 wt.-% led to an increased density of produced gelatin films and a decreasing water uptake of the films from 1160 wt.-% to 730 wt.-%, while the storage modulus was increasing about one order of magnitude from 440 Pa to 4090 Pa. The relative single and triple helix content was not influenced by the variation of polymer concentration.

Comment on “Relating side chain organization of PNIPAm with its conformation in aqueous methanol” by D. Mukherji, M. Wagner, M. D. Watson, S. Winzen, T. E. de Oliveira, C. M. Marques and K. Kremer, Soft Matter, 2016, 12, 7995

Soft Matter ◽  
2017 ◽  
Vol 13 (42) ◽  
pp. 7698-7700 ◽  
Author(s):  
Andrea Pica ◽  
Giuseppe Graziano
Keyword(s):  
Soft Matter ◽  
Side Chain ◽  
Aqueous Methanol ◽  
Chain Organization

We try to clarify some issues that were raised by an article that appeared in Soft Matter, 2016, 12, 7995. PNIPAM cononsolvency is not due to the bridging mechanism of MeOH molecules; it is caused by geometric-energetic frustration.

scholarly journals Relating side chain organization of PNIPAm with its conformation in aqueous methanol

Soft Matter ◽  
2016 ◽  
Vol 12 (38) ◽  
pp. 7995-8003 ◽  
Author(s):  
Debashish Mukherji ◽  
Manfred Wagner ◽  
Mark D. Watson ◽  
Svenja Winzen ◽  
Tiago E. de Oliveira ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Light Scattering ◽  
Magnetic Resonance ◽  
Dynamic Light Scattering ◽  
Side Chain ◽  
Aqueous Methanol ◽  
Chain Organization ◽  
Nuclear Magnetic

Combination of nuclear magnetic resonance, dynamic light scattering, and μs long all-atom simulations of 2 million particles reveal that the PNIPAm collapse in aqueous methanol mixtures is driven by enthalpy and the reopening at higher mole fractions of methanol is entropy driven.

Comment on “Relating side chain organization of PNIPAm with its conformation in aqueous methanol” by D. Mukherji, M. Wagner, M. D. Watson, S. Winzen, T. E. de Oliveira, C. M. Marques and K. Kremer, Soft Matter, 2016, 12, 7995

Soft Matter ◽  
2017 ◽  
Vol 13 (12) ◽  
pp. 2289-2291 ◽  
Author(s):  
Nico F. A. van der Vegt ◽  
Francisco Rodríguez-Ropero
Keyword(s):  
Soft Matter ◽  
Side Chain ◽  
Aqueous Methanol ◽  
Chain Organization

We try to clarify some issues that were raised by an article that appeared in Soft Matter, 2016, 12, 7995.

Permeability of Endometrial Blood Vessels to Exogenous Horse Radish Peroxidase in Mice. Electron Microscope Study

1973 ◽  
Vol 31 ◽  
pp. 562-563
Author(s):  
M.C. Castillo-Jessen ◽  
A. González-Angulo
Keyword(s):  
Electron Microscopy ◽  
Blood Vessels ◽  
Electron Microscope Study ◽  
Ultrastructural Level ◽  
Low Molecular Weight ◽  
Horse Radish Peroxidase ◽  
Intravascular Injection ◽  
Normal Morphology ◽  
Functional Implications ◽  
Low Molecular Weight Proteins

Information regarding the normal morphology of uterine blood vessels at ultrastructural level in mammals is scarce Electron microscopy studies dealing with endometrial vasculature despite the functional implications due to hormone priming are not available. Light microscopy observations with combined injection of dyes and microradiography along with histochemical studies does not enable us to know the detailed fine structure of the possible various types of blood vessels in this tissue. The present work has been designed to characterize the blood vessels of endometrium of mice as well as the behavior of the endothelium to injection of low molecular weight proteins during the normal estrous cycle in this animal. One hundred and forty female albino mice were sacrificed after intravascular injection of horse radish peroxidase (HRP) at 30 seconds, 5, 15, 30 and 60 minutes.

Intraindividual Variability and Stability of Affect and Well-Being

GeroPsych ◽  
2013 ◽  
Vol 26 (3) ◽  
pp. 185-199 ◽  
Author(s):  
Christina Röcke ◽  
Annette Brose
Keyword(s):  
Age Differences ◽  
Well Being ◽  
Subjective Well Being ◽  
Emotional Experiences ◽  
Short Term ◽  
Regulatory Processes ◽  
Functional Implications ◽  
Methodological Approaches ◽  
Underlying Processes

Whereas subjective well-being remains relatively stable across adulthood, emotional experiences show remarkable short-term variability, with younger and older adults differing in both amount and correlates. Repeatedly assessed affect data captures both the dynamics and stability as well as stabilization that may indicate emotion-regulatory processes. The article reviews (1) research approaches to intraindividual affect variability, (2) functional implications of affect variability, and (3) age differences in affect variability. Based on this review, we discuss how the broader literature on emotional aging can be better integrated with theories and concepts of intraindividual affect variability by using appropriate methodological approaches. Finally, we show how a better understanding of affect variability and its underlying processes could contribute to the long-term stabilization of well-being in old age.

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