Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2

Sophie E. Jackson; Marco Moracci; Nadia elMasry; Christopher M. Johnson; Alan R. Fersht

doi:10.1021/bi00093a001

Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2

Biochemistry ◽

10.1021/bi00093a001 ◽

1993 ◽

Vol 32 (42) ◽

pp. 11259-11269 ◽

Cited By ~ 198

Author(s):

Sophie E. Jackson ◽

Marco Moracci ◽

Nadia elMasry ◽

Christopher M. Johnson ◽

Alan R. Fersht

Keyword(s):

Hydrophobic Core ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2

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Structure of the hydrophobic core in the transition state for folding of chymotrypsin inhibitor 2: A critical test of the protein engineering method of analysis

Biochemistry ◽

10.1021/bi00093a002 ◽

1993 ◽

Vol 32 (42) ◽

pp. 11270-11278 ◽

Cited By ~ 100

Author(s):

Sophie E. Jackson ◽

Nadia elMasry ◽

Alan R. Fersht

Keyword(s):

Protein Engineering ◽

Transition State ◽

Engineering Method ◽

Hydrophobic Core ◽

Critical Test ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2

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Carbon-13 NMR study of the effects of mutation on the tryptophan dynamics in chymotrypsin inhibitor 2: correlations with structure and stability. [Erratum to document cited in CA118(5):34967r]

Biochemistry ◽

10.1021/bi00067a041 ◽

1993 ◽

Vol 32 (16) ◽

pp. 4474-4474

Author(s):

Stephen J. Matthews ◽

Sati K. Jandu ◽

Robin J. Leatherbarrow

Keyword(s):

Chymotrypsin Inhibitor ◽

Structure And Stability ◽

Chymotrypsin Inhibitor 2 ◽

Nmr Study

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Investigation of the solution structure of chymotrypsin inhibitor 2 using molecular dynamics: comparison to X-ray crystallographic and NMR data

Protein Engineering Design and Selection ◽

10.1093/protein/8.11.1117 ◽

1995 ◽

Vol 8 (11) ◽

pp. 1117-1128 ◽

Cited By ~ 33

Author(s):

Aijun Li ◽

Valerie Daggett

Keyword(s):

Molecular Dynamics ◽

Solution Structure ◽

Chymotrypsin Inhibitor ◽

X Ray ◽

Chymotrypsin Inhibitor 2 ◽

Nmr Data

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Direct Observation of Backbone Hydrogen Bonding in the Folding Transition of Chymotrypsin Inhibitor 2 (CI2)

Peptides: The Wave of the Future ◽

10.1007/978-94-010-0464-0_187 ◽

2001 ◽

pp. 404-405

Author(s):

Gangamani S. Beligere ◽

Radha Plachikkat ◽

Philip E. Dawson

Keyword(s):

Hydrogen Bonding ◽

Direct Observation ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2

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Mutational analysis of the N-capping box of the α-helix of chymotrypsin inhibitor 2

Protein Engineering Design and Selection ◽

10.1093/protein/7.6.777 ◽

1994 ◽

Vol 7 (6) ◽

pp. 777-782 ◽

Cited By ~ 23

Author(s):

Nadia F. elMasry ◽

Alan R. Fersht

Keyword(s):

Mutational Analysis ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2 ◽

Α Helix ◽

Capping Box

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Crystal and molecular structure of chymotrypsin inhibitor 2 from barley seeds in complex with subtilisin Novo

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.82.21.7242 ◽

1985 ◽

Vol 82 (21) ◽

pp. 7242-7246 ◽

Cited By ~ 87

Author(s):

C. A. McPhalen ◽

I. Svendsen ◽

I. Jonassen ◽

M. N. G. James

Keyword(s):

Molecular Structure ◽

Crystal And Molecular Structure ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2

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Direct Comparison of Experimental and Calculated Folding Free Energies for Hydrophobic Deletion Mutants of Chymotrypsin Inhibitor 2: Free Energy Perturbation Calculations Using Transition and Denatured States from Molecular Dynamics Simulations of Unfolding†

Biochemistry ◽

10.1021/bi0022036 ◽

2001 ◽

Vol 40 (9) ◽

pp. 2723-2731 ◽

Cited By ~ 37

Author(s):

YongPing Pan ◽

Valerie Daggett

Keyword(s):

Molecular Dynamics ◽

Free Energy ◽

Free Energy Perturbation ◽

Deletion Mutants ◽

Free Energies ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2 ◽

Energy Perturbation ◽

Dynamics Simulations ◽

Denatured States

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SNP Analysis and Haplotype Identification in Chymotrypsin Inhibitor-2 (CI-2) Gene of Barley

Agricultural Sciences in China ◽

10.1016/s1671-2927(09)60003-1 ◽

2009 ◽

Vol 8 (1) ◽

pp. 8-14 ◽

Cited By ~ 2

Author(s):

Xiang-hui ZENG ◽

Yu-ming WEI ◽

Qian-tao JIANG ◽

Peng-fei QI ◽

You-liang ZHENG

Keyword(s):

Snp Analysis ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2

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Spectroscopic Characterization of the Growing Polypeptide Chain of the Barley Chymotrypsin Inhibitor-2

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1996.0475 ◽

1996 ◽

Vol 335 (1) ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Gonzalo de Prat Gay

Keyword(s):

Polypeptide Chain ◽

Spectroscopic Characterization ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2

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Real-time NMR studies on folding of mutants of barnase and chymotrypsin inhibitor 2

FEBS Letters ◽

10.1016/s0014-5793(98)00075-1 ◽

1998 ◽

Vol 423 (1) ◽

pp. 110-112 ◽

Cited By ~ 16

Author(s):

Thomas R Killick ◽

Stefan M.V Freund ◽

Alan R Fersht

Keyword(s):

Real Time ◽

Nmr Studies ◽

Chymotrypsin Inhibitor ◽

Chymotrypsin Inhibitor 2

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