Substrate and cofactor reactivity of a carbon monoxide dehydrogenase-corrinoid enzyme complex: Stepwise reduction of iron-sulfur and corrinoid centers, the corrinoid cobalt(2+/1+) redox midpoint potential, and overall synthesis of acetyl-CoA

David A. Grahame

doi:10.1021/bi00091a033

Substrate and cofactor reactivity of a carbon monoxide dehydrogenase-corrinoid enzyme complex: Stepwise reduction of iron-sulfur and corrinoid centers, the corrinoid cobalt(2+/1+) redox midpoint potential, and overall synthesis of acetyl-CoA

Biochemistry ◽

10.1021/bi00091a033 ◽

1993 ◽

Vol 32 (40) ◽

pp. 10786-10793 ◽

Cited By ~ 18

Author(s):

David A. Grahame

Keyword(s):

Carbon Monoxide ◽

Carbon Monoxide Dehydrogenase ◽

Enzyme Complex ◽

Acetyl Coa ◽

Midpoint Potential ◽

Iron Sulfur ◽

Reduction Of Iron ◽

Stepwise Reduction ◽

Corrinoid Enzyme

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Catalysis of acetyl-CoA cleavage and tetrahydrosarcinapterin methylation by a carbon monoxide dehydrogenase-corrinoid enzyme complex.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54558-0 ◽

1991 ◽

Vol 266 (33) ◽

pp. 22227-22233

Author(s):

D.A. Grahame

Keyword(s):

Carbon Monoxide ◽

Carbon Monoxide Dehydrogenase ◽

Enzyme Complex ◽

Acetyl Coa ◽

Corrinoid Enzyme

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Binding of Carbon Disulfide to the Site of Acetyl-CoA Synthesis by the Nickel-Iron-Sulfur Protein, Carbon Monoxide Dehydrogenase, from Clostridium thermoaceticum

Biochemistry ◽

10.1021/bi00198a048 ◽

1994 ◽

Vol 33 (32) ◽

pp. 9769-9777 ◽

Cited By ~ 29

Author(s):

Manoj Kumar ◽

Wei-Ping Lu ◽

Stephen W. Ragsdale

Keyword(s):

Carbon Monoxide ◽

Carbon Disulfide ◽

Carbon Monoxide Dehydrogenase ◽

Clostridium Thermoaceticum ◽

Acetyl Coa ◽

Nickel Iron ◽

Iron Sulfur ◽

Acetyl Coa Synthesis ◽

Sulfur Protein ◽

Iron Sulfur Protein

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Nickel–iron–sulfur complexes: approaching structural analogues of the active sites of NiFe-hydrogenase and carbon monoxide dehydrogenase/acetyl-CoA synthase

Journal of the Chemical Society Dalton Transactions ◽

10.1039/b201578c ◽

2002 ◽

pp. 2641-2647 ◽

Cited By ~ 40

Author(s):

Matt C. Smith ◽

J. Elaine Barclay ◽

Stephen P. Cramer ◽

Sian C. Davies ◽

Wei-Wei Gu ◽

...

Keyword(s):

Carbon Monoxide ◽

Active Sites ◽

Carbon Monoxide Dehydrogenase ◽

Acetyl Coa ◽

Nickel Iron ◽

Iron Sulfur ◽

Structural Analogues

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EPR properties of the Ni-Fe-C center in an enzyme complex with carbon monoxide dehydrogenase activity from acetate-grown Methanosarcina thermophila. Evidence that acetyl-CoA is a physiological substrate.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)47737-x ◽

1987 ◽

Vol 262 (32) ◽

pp. 15392-15395 ◽

Cited By ~ 10

Author(s):

K C Terlesky ◽

M J Barber ◽

D J Aceti ◽

J G Ferry

Keyword(s):

Carbon Monoxide ◽

Dehydrogenase Activity ◽

Carbon Monoxide Dehydrogenase ◽

Enzyme Complex ◽

Acetyl Coa ◽

Methanosarcina Thermophila ◽

C Center

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Faculty Opinions recommendation of A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1010023.144457 ◽

2002 ◽

Author(s):

Wolfgang Buckel

Keyword(s):

Carbon Monoxide ◽

Carbon Monoxide Dehydrogenase ◽

Acetyl Coa

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Faculty Opinions recommendation of Inactivation of acetyl-CoA synthase/carbon monoxide dehydrogenase by copper.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1014843.195580 ◽

2003 ◽

Author(s):

Bruce Averill

Keyword(s):

Carbon Monoxide ◽

Carbon Monoxide Dehydrogenase ◽

Acetyl Coa

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Faculty Opinions recommendation of Inactivation of acetyl-CoA synthase/carbon monoxide dehydrogenase by copper.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1014843.194902 ◽

2003 ◽

Author(s):

Mark Nelson

Keyword(s):

Carbon Monoxide ◽

Carbon Monoxide Dehydrogenase ◽

Acetyl Coa

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Faculty Opinions recommendation of Evolutionary history of carbon monoxide dehydrogenase/acetyl-CoA synthase, one of the oldest enzymatic complexes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732542593.793554368 ◽

2018 ◽

Author(s):

Frank Robb

Keyword(s):

Carbon Monoxide ◽

Evolutionary History ◽

Carbon Monoxide Dehydrogenase ◽

Acetyl Coa ◽

History Of

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Properties of purified carbon monoxide dehydrogenase from Clostridium thermoaceticum, a nickel, iron-sulfur protein.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)32932-6 ◽

1983 ◽

Vol 258 (4) ◽

pp. 2364-2369 ◽

Cited By ~ 16

Author(s):

S W Ragsdale ◽

J E Clark ◽

L G Ljungdahl ◽

L L Lundie ◽

H L Drake

Keyword(s):

Carbon Monoxide ◽

Carbon Monoxide Dehydrogenase ◽

Clostridium Thermoaceticum ◽

Nickel Iron ◽

Iron Sulfur ◽

Sulfur Protein ◽

Iron Sulfur Protein

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Nickel-containing carbon monoxide dehydrogenase catalyzes reversible decarbonylation of acetyl CoA with retention of stereochemistry at the methyl group

Journal of the American Chemical Society ◽

10.1021/ja00244a065 ◽

1987 ◽

Vol 109 (10) ◽

pp. 3171-3173 ◽

Cited By ~ 23

Author(s):

Scott A. Raybuck ◽

Neil R. Bastian ◽

Lynne D. Zydowsky ◽

Koji Kobayashi ◽

Heinz G. Floss ◽

...

Keyword(s):

Carbon Monoxide ◽

Carbon Monoxide Dehydrogenase ◽

Acetyl Coa ◽

Methyl Group

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