Kinetic Analysis of cAMP-Dependent Protein Kinase: Mutations at Histidine 87 Affect Peptide Binding and pH Dependence

Sarah Cox; Susan S. Taylor

doi:10.1021/bi00049a036

Kinetic Analysis of cAMP-Dependent Protein Kinase: Mutations at Histidine 87 Affect Peptide Binding and pH Dependence

Biochemistry ◽

10.1021/bi00049a036 ◽

1995 ◽

Vol 34 (49) ◽

pp. 16203-16209 ◽

Cited By ~ 28

Author(s):

Sarah Cox ◽

Susan S. Taylor

Keyword(s):

Protein Kinase ◽

Kinetic Analysis ◽

Ph Dependence ◽

Peptide Binding ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Probing the peptide binding site of the cAMP-dependent protein kinase by using a peptide-based photoaffinity label.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.85.15.5429 ◽

1988 ◽

Vol 85 (15) ◽

pp. 5429-5433 ◽

Cited By ~ 35

Author(s):

W. T. Miller ◽

E. T. Kaiser

Keyword(s):

Protein Kinase ◽

Binding Site ◽

Peptide Binding ◽

Dependent Protein Kinase ◽

Photoaffinity Label ◽

Camp Dependent Protein Kinase ◽

Peptide Binding Site ◽

Dependent Protein

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Pre-Steady-State Kinetic Analysis of cAMP-Dependent Protein Kinase Using Rapid Quench Flow Techniques†

Biochemistry ◽

10.1021/bi952144+ ◽

1996 ◽

Vol 35 (6) ◽

pp. 2022-2029 ◽

Cited By ~ 54

Author(s):

Bruce D. Grant ◽

Joseph A. Adams

Keyword(s):

Steady State ◽

Protein Kinase ◽

Kinetic Analysis ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Rapid Quench ◽

Steady State Kinetic ◽

Dependent Protein ◽

State Kinetic ◽

Flow Techniques

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Kinetic analysis of inhibition of cAMP-dependent protein kinase catalytic subunit by the peptide–nucleoside conjugate AdcAhxArg6

Bioorganic Chemistry ◽

10.1016/j.bioorg.2004.05.004 ◽

2004 ◽

Vol 32 (6) ◽

pp. 527-535 ◽

Cited By ~ 9

Author(s):

Aleksei Kuznetsov ◽

Asko Uri ◽

Gerda Raidaru ◽

Jaak Järv

Keyword(s):

Protein Kinase ◽

Kinetic Analysis ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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cAMP exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A and exchange proteins directly activated by cAMP

Endocrine Abstracts ◽

10.1530/endoabs.32.p827 ◽

2013 ◽

Author(s):

Eleonora Vitali ◽

Erika Peverelli ◽

Giovanna Mantovani ◽

Elena Giardino ◽

Andrea G. Lania ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Pituitary Cells ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Different Types ◽

Dependent Protein ◽

Kinase A

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Faculty Opinions recommendation of Distal recognition sites in substrates are required for efficient phosphorylation by the cAMP-dependent protein kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1165205.628140 ◽

2009 ◽

Author(s):

Jonathan Chernoff

Keyword(s):

Protein Kinase ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Recognition Sites ◽

Dependent Protein

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Faculty Opinions recommendation of Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718291698.793492090 ◽

2014 ◽

Author(s):

Johannes Hell

Keyword(s):

Protein Kinase ◽

Differential Regulation ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Anchoring Proteins ◽

Dependent Protein ◽

Cav1.2 Channels

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Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus.

The EMBO Journal ◽

10.1002/j.1460-2075.1985.tb04006.x ◽

1985 ◽

Vol 4 (11) ◽

pp. 2801-2806 ◽

Cited By ~ 217

Author(s):

E.A. Nigg ◽

H. Hilz ◽

H.M. Eppenberger ◽

F. Dutly

Keyword(s):

Protein Kinase ◽

Golgi Complex ◽

Catalytic Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Thalamocortical projections have a K+ channel that is phosphorylated and modulated by cAMP-dependent protein kinase

Journal of Neuroscience ◽

10.1523/jneurosci.15-08-05486.1995 ◽

1995 ◽

Vol 15 (8) ◽

pp. 5486-5501 ◽

Cited By ~ 48

Author(s):

H Moreno ◽

C Kentros ◽

E Bueno ◽

M Weiser ◽

A Hernandez ◽

...

Keyword(s):

Protein Kinase ◽

K Channel ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Thalamocortical Projections ◽

Dependent Protein

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Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)83888-7 ◽

1986 ◽

Vol 261 (18) ◽

pp. 8140-8145 ◽

Cited By ~ 1

Author(s):

D K Blumenthal ◽

K Takio ◽

R S Hansen ◽

E G Krebs

Keyword(s):

Protein Kinase ◽

Substrate Specificity ◽

Protein Phosphatase ◽

Regulatory Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Glutamic acid 203 of the cAMP-dependent protein kinase catalytic subunit participates in the inhibition by two isoforms of the protein kinase inhibitor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42170-3 ◽

1994 ◽

Vol 269 (3) ◽

pp. 2316-2323

Author(s):

E.J. Baude ◽

S.S. Dignam ◽

S.R. Olsen ◽

E.M. Reimann ◽

M.D. Uhler

Keyword(s):

Protein Kinase ◽

Glutamic Acid ◽

Kinase Inhibitor ◽

Protein Kinase Inhibitor ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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