Transfer of specific endothelial cell-binding properties from the procoagulant protein human factor IX into the anticoagulant protein human protein C

Biochemistry ◽  
1995 ◽  
Vol 34 (26) ◽  
pp. 8449-8457 ◽  
Author(s):  
Jie-Ping Geng ◽  
William T. Christiansen ◽  
Edward F. Plow ◽  
Francis J. Castellino
Keyword(s):  
Endothelial Cell ◽  
Protein C ◽  
Human Factor ◽  
Factor Ix ◽  
Human Protein ◽  
Cell Binding ◽  
Binding Properties ◽  
Human Factor Ix

The endothelial cell binding determinant of human factor IX resides in the .gamma.-carboxyglutamic acid domain

Biochemistry ◽  
1992 ◽  
Vol 31 (6) ◽  
pp. 1806-1808 ◽  
Author(s):  
John R. Toomey ◽  
Kenneth J. Smith ◽  
Harold R. Roberts ◽  
Darrel W. Stafford
Keyword(s):  
Endothelial Cell ◽  
Human Factor ◽  
Factor Ix ◽  
Cell Binding ◽  
Human Factor Ix ◽  
Carboxyglutamic Acid ◽  
Acid Domain

scholarly journals Expression and characterization of human factor IX. Factor IXthr-397 and factor IXval-397

1991 ◽  
Vol 266 (23) ◽  
pp. 15213-15220
Author(s):  
N. Hamaguchi ◽  
P.S. Charifson ◽  
L.G. Pedersen ◽  
G.D. Brayer ◽  
K.J. Smith ◽  
...  
Keyword(s):  
Human Factor ◽  
Factor Ix ◽  
Human Factor Ix

scholarly journals Tyrosine 69 of the first epidermal growth factor-like domain of human factor IX is essential for clotting activity.

1993 ◽  
Vol 268 (24) ◽  
pp. 17727-17733
Author(s):  
P.E. Hughes ◽  
G. Morgan ◽  
E.K. Rooney ◽  
G.G. Brownlee ◽  
P. Handford
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Human Factor ◽  
Factor Ix ◽  
Human Factor Ix ◽  
Epidermal Growth

scholarly journals The binding of human factor IX to endothelial cells is mediated by residues 3-11.

1992 ◽  
Vol 267 (29) ◽  
pp. 20529-20531
Author(s):  
W.F. Cheung ◽  
N Hamaguchi ◽  
K.J. Smith ◽  
D.W. Stafford
Keyword(s):  
Endothelial Cells ◽  
Human Factor ◽  
Factor Ix ◽  
Human Factor Ix
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