Isomorphous Crystal Structures of Escherichia coli Dihydrofolate Reductase Complexed with Folate, 5-Deazafolate, and 5,10-Dideazatetrahydrofolate: Mechanistic Implications

Biochemistry ◽  
1995 ◽  
Vol 34 (8) ◽  
pp. 2710-2723 ◽  
Author(s):  
Vicente M. Reyes ◽  
Michael R. Sawaya ◽  
Katherine A. Brown ◽  
Joseph Kraut
Keyword(s):  
Escherichia Coli ◽  
Crystal Structures ◽  
Dihydrofolate Reductase

A study on the inhibition of dihydrofolate reductase (DHFR) from Escherichia coli by gold(i) phosphane compounds. X-ray crystal structures of (4,5-dichloro-1H-imidazolate-1-yl)-triphenylphosphane-gold(i) and (4,5-dicyano-1H-imidazolate-1-yl)-triphenylphosphane-gold(i)

2015 ◽  
Vol 44 (7) ◽  
pp. 3043-3056 ◽  
Author(s):  
Rossana Galassi ◽  
Camille Simon Oumarou ◽  
Alfredo Burini ◽  
Alessandro Dolmella ◽  
Daniela Micozzi ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Crystal Structures ◽  
Dihydrofolate Reductase ◽  
X Ray

A study on the inhibition of dihydrofolate reductase (DHFR) by gold(i) compounds has been performed.

scholarly journals Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

1985 ◽  
Vol 260 (1) ◽  
pp. 381-391 ◽  
Author(s):  
D A Matthews ◽  
J T Bolin ◽  
J M Burridge ◽  
D J Filman ◽  
K W Volz ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Crystal Structures ◽  
Dihydrofolate Reductase ◽  
Chicken Liver

scholarly journals Role of aspartate 27 in the binding of methotrexate to dihydrofolate reductase from Escherichia coli.

1988 ◽  
Vol 263 (19) ◽  
pp. 9187-9198 ◽  
Author(s):  
J R Appleman ◽  
E E Howell ◽  
J Kraut ◽  
M Kühl ◽  
R L Blakley
Keyword(s):  
Escherichia Coli ◽  
Dihydrofolate Reductase
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