scholarly journals In Situ Synthesis of Peptide Nucleic Acids in Porous Silicon for Drug Delivery and Biosensing

2014 ◽  
Vol 25 (7) ◽  
pp. 1192-1197 ◽  
Author(s):  
Kelsey R. Beavers ◽  
Jeremy W. Mares ◽  
Caleb M. Swartz ◽  
Yiliang Zhao ◽  
Sharon M. Weiss ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
In Situ Synthesis

A new compact disc format of high density array synthesis applied to peptide nucleic acids and in situ MALDI analysis

2004 ◽  
Vol 8 (3) ◽  
pp. 197-207 ◽  
Author(s):  
Antonius J. Dikmans ◽  
Michael Morr ◽  
Norbert Zander ◽  
Frank Adler ◽  
Gerhard Türk ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Compact Disc ◽  
High Density ◽  
Maldi Analysis

scholarly journals Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids

2020 ◽  
Vol 12 (35) ◽  
pp. 39602-39611 ◽  
Author(s):  
Isom B. Kelly ◽  
R. Brock Fletcher ◽  
James R. McBride ◽  
Sharon M. Weiss ◽  
Craig L. Duvall
Keyword(s):  
Porous Silicon ◽  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Early Endosome ◽  
Composite Nanoparticles ◽  
Endosome Escape

In situ synthesis of carbon doped porous silicon nanocomposites as high-performance anodes for lithium-ion batteries

2018 ◽  
Vol 30 (3) ◽  
pp. 035602 ◽  
Author(s):  
Yifan Chen ◽  
Liang Bao ◽  
Ning Du ◽  
Tao Yang ◽  
Qinan Mao ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Lithium Ion Batteries ◽  
High Performance ◽  
Lithium Ion ◽  
In Situ Synthesis ◽  
Carbon Doped

scholarly journals The Use of Peptide Nucleic Acids for In Situ Identification of Human Chromosomes

2005 ◽  
Vol 53 (3) ◽  
pp. 395-400 ◽  
Author(s):  
Franck Pellestor ◽  
Petra Paulasova ◽  
Milan Macek ◽  
Samir Hamamah
Keyword(s):  
Nucleic Acids ◽  
Dna Sequences ◽  
Genome Mapping ◽  
Peptide Nucleic Acids ◽  
Human Lymphocytes ◽  
Human Chromosomes ◽  
Great Resistance ◽  
Diagnostic Assays ◽  
New Class

The peptide nucleic acids (PNAs) constitute a remarkable new class of synthetic nucleic acid analogues, based on their peptide-like backbone. This structure gives to PNAs the capacity to hybridize with high affinity and specificity to complementary RNA and DNA sequences and a great resistance to nucleases and proteinases. Originally conceived as ligands for the study of double-stranded DNA, the unique physicochemical properties of PNAs have led to the development of a large variety of research and diagnostic assays, including antigene and antisense therapy, genome mapping, and mutation detection. Over the past few years, PNAs have been shown to be powerful tools in cytogenetics for the rapid in situ identification of human chromosomes and the detection of aneuploidies. Recent studies have reported the successful use of chromosome-specific PNA probes on human lymphocytes, amniocytes, and spermatozoa, as well as on isolated oocytes and blastomeres. Multicolor PNA protocols have been described for the identification of several human chromosomes, indicating that PNAs could become a powerful complement to FISH for in situ chromosomal investigation.

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