Active Accumulation of Gold Nanorods in Tumor in Response to Near-Infrared Laser Irradiation

2010 ◽  
Vol 21 (11) ◽  
pp. 2049-2054 ◽  
Author(s):  
Atsushi Shiotani ◽  
Yasuyuki Akiyama ◽  
Takahito Kawano ◽  
Yasuro Niidome ◽  
Takeshi Mori ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Laser ◽  
Infrared Laser Irradiation ◽  
Active Accumulation

Stable Incorporation of Gold Nanorods intoN-Isopropylacrylamide Hydrogels and Their Rapid Shrinkage Induced by Near-Infrared Laser Irradiation

Langmuir ◽  
2007 ◽  
Vol 23 (7) ◽  
pp. 4012-4018 ◽  
Author(s):  
Atsushi Shiotani ◽  
Takeshi Mori ◽  
Takuro Niidome ◽  
Yasuro Niidome ◽  
Yoshiki Katayama
Keyword(s):  
Laser Irradiation ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Laser ◽  
Infrared Laser Irradiation ◽  
Stable Incorporation

scholarly journals Light-Activatable Transfection System Using Hybrid Vectors Composed of Thermosensitive Dendron Lipids and Gold Nanorods

Pharmaceutics ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 239
Author(s):  
Takuya Hashimoto ◽  
Tomoya Hirata ◽  
Eiji Yuba ◽  
Atsushi Harada ◽  
Kenji Kono
Keyword(s):  
Laser Irradiation ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Laser ◽  
Target Cells ◽  
Temperature Responsive ◽  
Hybrid Vectors ◽  
Transfection Efficacy ◽  
Infrared Laser Irradiation ◽  
Gene Vectors

Background: Gene delivery to target cells is crucially important to establish gene therapy and regenerative medicine. Although various virus-based and synthetic molecule-based gene vectors have been developed to date, selective transfection in a site or a cell level is still challenging. For this study, both light-responsive and temperature-responsive synthetic gene vectors were designed for spatiotemporal control of a transfection system. Methods: 11-Mercaptoundecanoic acid-coated gold nanorods were mixed with polyamidoamine dendron-bearing lipids of two types having amino-terminus or ethoxydiethylene glycol-terminus to obtain hybrid vectors. Hybrid vectors were mixed further with pDNA. Then we investigated their physicochemical properties and transfection efficacy with or without near infrared laser irradiation. Results: Hybrid vectors formed complexes with pDNA and exhibited enhanced photothermal property under near infrared laser irradiation compared with parent gold nanorods. Transfection efficacy of complexes was promoted considerably by brief laser irradiation soon after complex application to the cells. Analysis of intracellular distribution revealed that laser irradiation promoted the adsorption of complexes to the cells and cytosolic release of pDNA, which is derived from the change in surface hydrophobicity of complexes through dehydration of temperature-responsive groups. Conclusions: Hybrid vector is promising as a light-activatable transfection system.

scholarly journals Near-infrared laser-mediated drug release and antibacterial activity of gold nanorod–sputtered titania nanotubes

2018 ◽  
Vol 9 ◽  
pp. 204173141879031 ◽  
Author(s):  
Kyoung-Suk Moon ◽  
Young-Bum Park ◽  
Ji-Myung Bae ◽  
Seunghan Oh
Keyword(s):  
Electron Microscopy ◽  
Laser Irradiation ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Region ◽  
Infrared Laser ◽  
Gold Nanorod ◽  
Titania Nanotubes ◽  
Infrared Laser Irradiation ◽  
Near Infrared Region

The infection control of implants is one of the hot issues in the field of medicine and dentistry. In this study, we prepared gold nanorod–sputtered titania nanotubes on titanium surface, which is the main component of implant material, and aimed to estimate the remote-controlled tetracycline release and resulting antibacterial effects of gold nanorod–sputtered titania nanotubes using near-infrared laser irradiation. Gold nanorods prepared by ion plasma sputtering (aspect ratio = 1:3) showed optical properties like those of chemically synthesized gold nanorods, exhibiting photothermal effects in the near-infrared region, as demonstrated using field-emission scanning electron microscopy, transmission electron microscopy, and diffuse ultraviolet–visible–near-infrared spectrophotometry. In addition, a 2 wt% tetracycline/polycaprolactone mixture was found to be the most suitable experimental group to demonstrate the biological compatibilities and antibacterial activities. The results of antibacterial agar diffusion tests and near-infrared-mediated tetracycline release tests in vivo confirmed that remote-controlled tetracycline elution using near-infrared laser irradiation was highly effective. Therefore, gold nanorod–sputtered titania nanotubes would be expected to enable the continued use of the photothermal therapy of gold nanorods and extend the limited use of titania showing photocatalytic activity only within the ultraviolet-to-near-infrared region.

Near infrared laser irradiation induces NETosis via oxidative stress and autophagy

2018 ◽  
Vol 33 (9) ◽  
pp. 1919-1924 ◽  
Author(s):  
Mario Migliario ◽  
Stelvio Tonello ◽  
Vincenzo Rocchetti ◽  
Manuela Rizzi ◽  
Filippo Renò
Keyword(s):  
Oxidative Stress ◽  
Laser Irradiation ◽  
Near Infrared ◽  
Infrared Laser ◽  
Infrared Laser Irradiation

Facile synthesis of monodisperse chromogenic amylose–iodine nanoparticles as an efficient broad-spectrum antibacterial agent

2020 ◽  
Vol 8 (15) ◽  
pp. 3010-3015
Author(s):  
Yanbin Sun ◽  
Xianwen Wang ◽  
Linxin Fan ◽  
Xianli Xie ◽  
Zhaohua Miao ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Broad Spectrum ◽  
Antibacterial Agent ◽  
Near Infrared ◽  
Infrared Laser ◽  
Facile Synthesis ◽  
Infrared Laser Irradiation

Monodisperse chromogenic amylose–iodine nanoparticles were developed as an efficient broad-spectrum antibacterial agent under the assistance of near-infrared laser irradiation.

Targeted increase in cerebral blood flow by transcranial near-infrared laser irradiation

2010 ◽  
Vol 42 (6) ◽  
pp. 566-576 ◽  
Author(s):  
Yoichi Uozumi ◽  
Hiroshi Nawashiro ◽  
Shunichi Sato ◽  
Satoko Kawauchi ◽  
Katsuji Shima ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Laser Irradiation ◽  
Near Infrared ◽  
Infrared Laser ◽  
Infrared Laser Irradiation

Thermal effects of transcranial near-infrared laser irradiation on rabbit cortex

2013 ◽  
Vol 553 ◽  
pp. 99-103 ◽  
Author(s):  
Yongmei Chen ◽  
Luis De Taboada ◽  
Michael O’Connor ◽  
Scott Delapp ◽  
Justin A. Zivin
Keyword(s):  
Laser Irradiation ◽  
Thermal Effects ◽  
Near Infrared ◽  
Infrared Laser ◽  
Infrared Laser Irradiation
Sign in / Sign up

Export Citation Format

Share Document