Peptide Nucleic Acid (PNA) Amphiphiles:  Synthesis, Self-Assembly, and Duplex Stability

2004 ◽  
Vol 15 (6) ◽  
pp. 1314-1321 ◽  
Author(s):  
James P. Vernille ◽  
Lara C. Kovell ◽  
James W. Schneider
Keyword(s):  
Nucleic Acid ◽  
Self Assembly ◽  
Peptide Nucleic Acid ◽  
Duplex Stability

Synthesis, Characterization, Investigation of Capacitance and Redox Properties of Self-assembled Phe-Phe with Ferrocene Conjugates

2021 ◽  
Author(s):  
Om Shanker Tiwari
Keyword(s):  
Nucleic Acid ◽  
Electrochemical Properties ◽  
Self Assembly ◽  
Peptide Nucleic Acid ◽  
Redox Properties ◽  
Self Assembled ◽  
Acid Unit

The synthesis, nanostructure self-assembly and electrochemical properties of a series of ferrocene conjugated peptides derived from the dipeptide Phe-Phe, nucleoside and the peptide nucleic acid unit which are covalently attached...

Supramolecular Nanodrugs Constructed by Self-Assembly of Peptide Nucleic Acid–Photosensitizer Conjugates for Photodynamic Therapy

2019 ◽  
Vol 3 (1) ◽  
pp. 2-9 ◽  
Author(s):  
Rui Chang ◽  
Emmanouil Nikoloudakis ◽  
Qianli Zou ◽  
Anna Mitraki ◽  
Athanassios G. Coutsolelos ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Nucleic Acid ◽  
Self Assembly ◽  
Peptide Nucleic Acid

Self‐Assembly of Di‐Guanine Peptide Nucleic Acid Amphiphiles into Fractal Patterns

2019 ◽  
Vol 4 (46) ◽  
pp. 13525-13532 ◽  
Author(s):  
Jancy N. Abraham ◽  
Prabhakar Pawar ◽  
Dilna K. Kootteri
Keyword(s):  
Nucleic Acid ◽  
Self Assembly ◽  
Peptide Nucleic Acid ◽  
Fractal Patterns

Self-Assembly of Hybridized Peptide Nucleic Acid Amphiphiles

2014 ◽  
Vol 3 (5) ◽  
pp. 467-471 ◽  
Author(s):  
Li-Han Liu ◽  
Ze-Yong Li ◽  
Lei Rong ◽  
Si-Yong Qin ◽  
Qi Lei ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Self Assembly ◽  
Peptide Nucleic Acid

scholarly journals Statistical Measurement of Peptide Nucleic Acid-Assisted Self-Assembly of Gold Nanocluster Dimers

2018 ◽  
Vol 24 (S1) ◽  
pp. 1692-1693
Author(s):  
Stephen D. House ◽  
Dilhara R. Jayarathna ◽  
Catalina Achim ◽  
Judith C. Yang
Keyword(s):  
Nucleic Acid ◽  
Self Assembly ◽  
Peptide Nucleic Acid ◽  
Gold Nanocluster ◽  
Statistical Measurement

Functionally Engineered Carbon Nanotubes-Peptide Nucleic Acid Nanocomponents

2005 ◽  
Vol 872 ◽  
Author(s):  
Krishna V. Singh ◽  
Xu Wang ◽  
Rajeev R. Pandey ◽  
Roger Lake ◽  
Cengiz S. Ozkan ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acid ◽  
Self Assembly ◽  
Peptide Nucleic Acid ◽  
Single Walled Carbon Nanotubes ◽  
Artificial Dna ◽  
Semi Empirical ◽  
Walled Carbon Nanotubes ◽  
Scanning Electron ◽  
Carbodiimide Coupling

AbstractConjugation of carbon nanotubes (CNTs) with biomolecules having molecular recognition results in highly functionalized CNTs, which serve as the templates for self-assembly of novel nanomaterials. Here, we report the synthesis of novel nanocomponents by conjugating single walled carbon nanotubes (SWNTs) with peptide nucleic acid (PNA), an artificial DNA analogue by using carbodiimide coupling. Scanning electron microscopy (SEM) is used as a primary tool for their characterization. SEM micrographs confirm the formation of desired structures. We also modeled and simulated the SWNT-PNA interface using the PM3 semi-empirical package in Gaussian03 RevB.03 program suite for electron transfer and found that there exists an extended set of orbitals.

scholarly journals Self-Assembly of Diphenylalanine–Peptide Nucleic Acid Conjugates

ACS Omega ◽  
2019 ◽  
Vol 4 (6) ◽  
pp. 10715-10728 ◽  
Author(s):  
Dhrubajyoti Datta ◽  
Omshanker Tiwari ◽  
Manoj Kumar Gupta
Keyword(s):  
Nucleic Acid ◽  
Self Assembly ◽  
Peptide Nucleic Acid

scholarly journals Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Vasantha Basavalingappa ◽  
Santu Bera ◽  
Bin Xue ◽  
Ido Azuri ◽  
Yiming Tang ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Atomic Structure ◽  
Self Assembly ◽  
Peptide Nucleic Acid ◽  
Supramolecular Assemblies ◽  
New Materials ◽  
Structural Patterns ◽  
Mechanical Rigidity ◽  
Hydrogen Bonded

AbstractThe variety and complexity of DNA-based structures make them attractive candidates for nanotechnology, yet insufficient stability and mechanical rigidity, compared to polyamide-based molecules, limit their application. Here, we combine the advantages of polyamide materials and the structural patterns inspired by nucleic-acids to generate a mechanically rigid fluorenylmethyloxycarbonyl (Fmoc)-guanine peptide nucleic acid (PNA) conjugate with diverse morphology and photoluminescent properties. The assembly possesses a unique atomic structure, with each guanine head of one molecule hydrogen bonded to the Fmoc carbonyl tail of another molecule, generating a non-planar cyclic quartet arrangement. This structure exhibits an average stiffness of 69.6 ± 6.8 N m−1 and Young’s modulus of 17.8 ± 2.5 GPa, higher than any previously reported nucleic acid derived structure. This data suggests that the unique cation-free “basket” formed by the Fmoc-G-PNA conjugate can serve as an attractive component for the design of new materials based on PNA self-assembly for nanotechnology applications.

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