New Dental Composites Containing Multimethacrylate Derivatives of Bile Acids: A Comparative Study with Commercial Monomers

2009 ◽  
Vol 1 (4) ◽  
pp. 824-832 ◽  
Author(s):  
Marc A. Gauthier ◽  
Zhao Zhang ◽  
X. X. Zhu
Keyword(s):  
Comparative Study ◽  
Bile Acids ◽  
Dental Composites ◽  
Derivatives Of

scholarly journals Bile acids as constituents for dental composites: in vitro cytotoxicity of (meth)acrylate and other ester derivatives of bile acids

2007 ◽  
Vol 4 (17) ◽  
pp. 1145-1150 ◽  
Author(s):  
Marc A Gauthier ◽  
Pierre Simard ◽  
Zhao Zhang ◽  
X.X Zhu
Keyword(s):  
Bile Acids ◽  
Entire Range ◽  
Degradation Products ◽  
Dental Materials ◽  
In Vitro Cytotoxicity ◽  
Dental Composites ◽  
3T3 Fibroblasts ◽  
The Common ◽  
Derivatives Of

Methacrylic derivatives of bile acids have been synthesized for use as monomers in dental composites. Polymeric dental materials are known to leach cytotoxic unreacted monomers and degradation products. In this study, the in vitro cytotoxicity of bile acids and their derivatives towards 3T3 fibroblasts has been evaluated by colorimetric MTT assay and compared with that of the common dental monomers BisGMA, UDMA and TEGDMA. In general, the bile acids and their derivatives induced mitochondrial dysfunction at similar or higher concentrations than the commercial dental monomers. Certain monomers did not influence MTT response over their entire range of solubility.

scholarly journals A comparative study of the sulfation of bile acids and a bile alcohol by the Zebra danio (Danio rerio) and human cytosolic sulfotransferases (SULTs)

2011 ◽  
Vol 127 (3-5) ◽  
pp. 307-314 ◽  
Author(s):  
Katsuhisa Kurogi ◽  
Matthew D. Krasowski ◽  
Elisha Injeti ◽  
Ming-Yih Liu ◽  
Frederick E. Williams ◽  
...  
Keyword(s):  
Comparative Study ◽  
Bile Acids ◽  
Danio Rerio ◽  
Bile Alcohol

scholarly journals Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors

Molecules ◽  
2018 ◽  
Vol 23 (3) ◽  
pp. 679 ◽  
Author(s):  
Oksana Salomatina ◽  
Irina Popadyuk ◽  
Alexandra Zakharenko ◽  
Olga Zakharova ◽  
Dmitriy Fadeev ◽  
...  
Keyword(s):  
Bile Acids ◽  
Derivatives Of

Comparative study of dG affinity vs. DNA methylation modulating properties of side chain derivatives of procainamide: insight into its DNA hypomethylating effect

RSC Advances ◽  
2016 ◽  
Vol 6 (7) ◽  
pp. 5350-5358 ◽  
Author(s):  
R. L. Gawade ◽  
D. K. Chakravarty ◽  
J. Debgupta ◽  
E. Sangtani ◽  
S. Narwade ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Comparative Study ◽  
Structural Features ◽  
Side Chain ◽  
Side Chains ◽  
Hypomethylating Agents ◽  
Derivatives Of ◽  
Insight Into

Structural features of side-chains govern the association of procainamide and its derivatives with dG base of CpG rich DNA, which may differentially hinder the activity of DNMT-1, thereby they act as DNA hypomethylating agents.

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