Fabrication of Single-Hole Glutathione-Responsive Degradable Hollow Silica Nanoparticles for Drug Delivery

2014 ◽  
Vol 6 (15) ◽  
pp. 12600-12608 ◽  
Author(s):  
Dongdong Wang ◽  
Zhigang Xu ◽  
Zhenjie Chen ◽  
Xiaoyan Liu ◽  
Cuilan Hou ◽  
...  

Silica nanoparticles with nanoporous nature are introduced as thermally and chemically stable nanomaterials with controllable porosity and morphology. The nanoparticles can be divided into three groups: microporous, mesoporous, and macroporous based on the porous size. The use of these materials for different applications is associated with their unique properties as disinfectants. This chapter discusses different synthesis methodologies to prepare well-dispersed mesoporous silica nanoparticles (MSNs) and hollow silica nanoparticles (HSNs) with tunable dimensions ranging from a few to hundreds of nanometers of different mesostructures. Several good characteristics of the MSNs, best biocompatibility and low toxicity, are proposed as the basis of the carrier for the controlled release of drugs, genes into living cells and bone regeneration.


Nano Letters ◽  
2017 ◽  
Vol 18 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Qian Liu ◽  
Claudia M. Santamaria ◽  
Tuo Wei ◽  
Chao Zhao ◽  
Tianjiao Ji ◽  
...  

2019 ◽  
Vol 553 ◽  
pp. 83-90 ◽  
Author(s):  
Yan Bao ◽  
Yuanxia Zhang ◽  
Pan Liu ◽  
Jianzhong Ma ◽  
Wenbo Zhang ◽  
...  

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