Synthesis, Mechanical Properties, and in Vitro Biocompatibility with Osteoblasts of Calcium Silicate–Reduced Graphene Oxide Composites

2014 ◽  
Vol 6 (6) ◽  
pp. 3947-3962 ◽  
Author(s):  
Mehdi Mehrali ◽  
Ehsan Moghaddam ◽  
Seyed Farid Seyed Shirazi ◽  
Saeid Baradaran ◽  
Mohammad Mehrali ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Calcium Silicate ◽  
In Vitro Biocompatibility ◽  
Reduced Graphene ◽  
Oxide Composites

Thermal and mechanical properties of copper-graphite and copper-reduced graphene oxide composites

2019 ◽  
Vol 163 ◽  
pp. 77-85 ◽  
Author(s):  
Faisal Nazeer ◽  
Zhuang Ma ◽  
Lihong Gao ◽  
Fuchi Wang ◽  
Muhammad Abubaker Khan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Thermal And Mechanical Properties ◽  
Reduced Graphene ◽  
Oxide Composites

Electrical and mechanical properties of poly(dopamine)-modified copper/reduced graphene oxide composites

2017 ◽  
Vol 52 (19) ◽  
pp. 11620-11629 ◽  
Author(s):  
Zhengfeng Jia ◽  
Haoqi Li ◽  
Yao Zhao ◽  
Laszlo Frazer ◽  
Bosen Qian ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Reduced Graphene ◽  
Oxide Composites

Electrophoretic deposition of calcium silicate–reduced graphene oxide composites on titanium substrate

2016 ◽  
Vol 36 (2) ◽  
pp. 319-332 ◽  
Author(s):  
Mehdi Mehrali ◽  
Amir Reza Akhiani ◽  
Sepehr Talebian ◽  
Mohammad Mehrali ◽  
Sara Tahan Latibari ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Electrophoretic Deposition ◽  
Calcium Silicate ◽  
Titanium Substrate ◽  
Reduced Graphene ◽  
Oxide Composites

scholarly journals Biomimetic reduced graphene oxide coated collagen scaffold for in situ bone regeneration

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sajad Bahrami ◽  
Nafiseh Baheiraei ◽  
Mostafa Shahrezaee
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Cranial Bone ◽  
Drying Methods ◽  
Porous Scaffolds ◽  
Alizarin Red ◽  
Reduced Graphene ◽  
Coated Collagen

AbstractA variety of bone-related diseases and injures and limitations of traditional regeneration methods require new tissue substitutes. Tissue engineering and regeneration combined with nanomedicine can provide different natural or synthetic and combined scaffolds with bone mimicking properties for implantation in the injured area. In this study, we synthesized collagen (Col) and reduced graphene oxide coated collagen (Col-rGO) scaffolds, and we evaluated their in vitro and in vivo effects on bone tissue repair. Col and Col-rGO scaffolds were synthesized by chemical crosslinking and freeze-drying methods. The surface topography, and the mechanical and chemical properties of scaffolds were characterized, showing three-dimensional (3D) porous scaffolds and successful coating of rGO on Col. The rGO coating enhanced the mechanical strength of Col-rGO scaffolds to a greater extent than Col scaffolds by 2.8 times. Furthermore, Col-rGO scaffolds confirmed that graphene addition induced no cytotoxic effects and enhanced the viability and proliferation of human bone marrow-derived mesenchymal stem cells (hBMSCs) with 3D adherence and expansion. Finally, scaffold implantation into rabbit cranial bone defects for 12 weeks showed increased bone formation, confirmed by Hematoxylin–Eosin (H&E) and alizarin red staining. Overall, the study showed that rGO coating improves Col scaffold properties and could be a promising implant for bone injuries.

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