Patterned Substrates of Nano-Graphene Oxide Mediating Highly Localized and Efficient Gene Delivery

2014 ◽  
Vol 6 (8) ◽  
pp. 5900-5907 ◽  
Author(s):  
Kunyang Li ◽  
Liangzhu Feng ◽  
Jianwei Shen ◽  
Qi Zhang ◽  
Zhuang Liu ◽  
...  
RSC Advances ◽  
2015 ◽  
Vol 5 (62) ◽  
pp. 50196-50211 ◽  
Author(s):  
Kishor Sarkar ◽  
Giridhar Madras ◽  
Kaushik Chatterjee

Owing to its large surface area and rapid cellular uptake, graphene oxide (GO) is emerging as an attractive candidate material for delivery of drugs and genes.


Small ◽  
2013 ◽  
Vol 9 (11) ◽  
pp. 1989-1997 ◽  
Author(s):  
Liangzhu Feng ◽  
Xianzhu Yang ◽  
Xiaoze Shi ◽  
Xiaofang Tan ◽  
Rui Peng ◽  
...  

Nano Research ◽  
2012 ◽  
Vol 5 (10) ◽  
pp. 703-709 ◽  
Author(s):  
Xiang Zhou ◽  
Fabrice Laroche ◽  
Gerda E. M. Lamers ◽  
Vincenzo Torraca ◽  
Patrick Voskamp ◽  
...  

2020 ◽  
Vol Volume 14 ◽  
pp. 3087-3097
Author(s):  
Vida Mirzaie ◽  
Mehdi Ansari ◽  
Seyed Noureddin Nematollahi-Mahania ◽  
Mahshid Moballegh Nasery ◽  
Behzad Karimi ◽  
...  

2011 ◽  
Vol 21 (21) ◽  
pp. 7736 ◽  
Author(s):  
Biao Chen ◽  
Min Liu ◽  
Liming Zhang ◽  
Jie Huang ◽  
Jianlin Yao ◽  
...  

Author(s):  
Soumitra Satapathi ◽  
Rutusmita Mishra ◽  
Manisha Chatterjee ◽  
Partha Roy ◽  
Somesh Mohapatra

Nano-materials based drug delivery modalities to specific organs and tissues has become one of the critical endeavors in pharmaceutical research. Recently, two-dimensional graphene has elicited considerable research interest because of its potential application in drug delivery systems. Here we report, the drug delivery applications of PEGylated nano-graphene oxide (nGO-PEG), complexed with a multiphoton active and anti-cancerous diarylheptanoid drug curcumin. Specifically, graphene-derivatives were used as nanovectors for the delivery of the hydrophobic anticancer drug curcumin due to its high surface area and easy surface functionalization. nGO was synthesized by modified Hummer’s method and confirmed by XRD analysis. The formation of nGO, nGO-PEG and nGO-PEG-Curcumin complex were monitored through UV-vis, IR spectroscopy. MTT assay and AO/EB staining found that nGO-PEG-Curcumin complex afforded highly potent cancer cell killing in vitro with a human breast cancer cell line MCF7.


2015 ◽  
Vol 19 (18) ◽  
pp. 1828-1837 ◽  
Author(s):  
George V. Theodosopoulos ◽  
Panayiotis Bilalis ◽  
Georgios Sakellariou

Author(s):  
Guoxin Tan ◽  
Jiayang Li ◽  
Dandan Liu ◽  
Hao Pan ◽  
Renfang Zhu ◽  
...  

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