Manganese-Loaded Dual-Mesoporous Silica Spheres for Efficient T1- and T2-Weighted Dual Mode Magnetic Resonance Imaging

2013 ◽  
Vol 5 (20) ◽  
pp. 9942-9948 ◽  
Author(s):  
Dechao Niu ◽  
Xiaofeng Luo ◽  
Yongsheng Li ◽  
Xiaohang Liu ◽  
Xia Wang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mesoporous Silica ◽  
Silica Spheres ◽  
Resonance Imaging ◽  
Dual Mode ◽  
T1 And T2 ◽  
Mesoporous Silica Spheres

One-pot synthesis of magnetite-loaded dual-mesoporous silica spheres for T2-weighted magnetic resonance imaging and drug delivery

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 39719-39725 ◽  
Author(s):  
Xiaofeng Luo ◽  
Dechao Niu ◽  
Yao Wang ◽  
Yungang Zhai ◽  
Jianzhuang Chen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Drug Delivery ◽  
Magnetic Resonance ◽  
Mesoporous Silica ◽  
Silica Spheres ◽  
Resonance Imaging ◽  
One Pot ◽  
Weighted Magnetic Resonance Imaging ◽  
New Type ◽  
Mesoporous Silica Spheres

A new type of magnetite-loaded dual-mesoporous silica nanoplatform has been successfully developed for MR imaging and efficient drug delivery.

Redoxable heteronanocrystals functioning magnetic relaxation switch for activatable T1 and T2 dual-mode magnetic resonance imaging

Biomaterials ◽  
2016 ◽  
Vol 101 ◽  
pp. 121-130 ◽  
Author(s):  
Myeong-Hoon Kim ◽  
Hye-Young Son ◽  
Ga-Yun Kim ◽  
Kwangyeol Park ◽  
Yong-Min Huh ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Relaxation ◽  
Resonance Imaging ◽  
Dual Mode ◽  
T1 And T2

Evaluation of Relaxation Time Measurements by Magnetic Resonance Imaging

1987 ◽  
Vol 28 (3) ◽  
pp. 345-351 ◽  
Author(s):  
L. Kjær ◽  
C. Thomsen ◽  
O. Henriksen ◽  
P. Ring ◽  
M. Stubgaard ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Relaxation Time ◽  
Magnetic Resonance ◽  
Diffusion Processes ◽  
Relaxation Times ◽  
Gradient Field ◽  
Maximum Deviation ◽  
Resonance Imaging ◽  
T2 Relaxation ◽  
T1 And T2

Several circumstances may explain the great variation in reported proton T1 and T2 relaxation times usually seen. This study was designed to evaluate the accuracy of relaxation time measurements by magnetic resonance imaging (MRI) operating at 1.5 tesla. Using a phantom of nine boxes with different concentrations of CuSO4 and correlating the calculated T1 and T2 values with reference values obtained by two spectrometers (corrected to MRI-proton frequency=64 MHz) we found a maximum deviation of about 10 per cent. Measurements performed on a large water phantom in order to evaluate the homogeneity in the imaging plane showed a variation of less than 10 per cent within 10 cm from the centre of the magnet in all three imaging planes. Changing the gradient field strength apparently had no influence on the T2 values recorded. Consequently diffusion processes seem without significance. It is concluded that proton T1 and T2 relaxation times covering the majority of the biologic range can be measured by MRI with an overall accuracy of 5 to 10 per cent. Quality control studies along the lines indicated in this study are recommended.

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