Graphene Nanoplatelet-Induced Strengthening of UltraHigh Molecular Weight Polyethylene and Biocompatibility In vitro

2012 ◽  
Vol 4 (4) ◽  
pp. 2234-2241 ◽  
Author(s):  
Debrupa Lahiri ◽  
Rupak Dua ◽  
Cheng Zhang ◽  
Ignacio de Socarraz-Novoa ◽  
Ashwin Bhat ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Ultrahigh Molecular Weight Polyethylene ◽  
Graphene Nanoplatelet ◽  
Ultrahigh Molecular Weight

In Vitro Study Bioactivity of HA/UHMWPE Nanocomposites

2007 ◽  
Vol 342-343 ◽  
pp. 701-704
Author(s):  
Li Ming Fang ◽  
Yang Leng ◽  
Ping Gao
Keyword(s):  
Molecular Weight ◽  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
In Vitro Study ◽  
Ultrahigh Molecular Weight Polyethylene ◽  
Octacalcium Phosphate ◽  
Tof Sims ◽  
Ultrahigh Molecular Weight

Bioactivity of hydroxyapatite reinforced ultrahigh molecular weight polyethylene (HA/UHMWPE) nanocomposites with HA volume content of 10~50 % was evaluated by simulated body fluid (SBF) immersion. The effect of HA content on the capability for calcium phosphate (Ca- P) induction was studied. It was found that Ca-P deposition covered the whole surface of the composite with 30 vol. % of HA after immersion for 1 day and the layer grew to around 10 0m thick in one-week immersion, while there was few nucleus formed for composites with HA content lower than 30 vol. % after one-week immersion. The Ca-P structure was identified as octacalcium phosphate (OCP) by SEM, TEM, and ToF-SIMS.

scholarly journals Porous Ultrahigh Molecular Weight Polyethylene/Functionalized Activated Nanocarbon Composites with Improved Biocompatibility

Materials ◽  
2021 ◽  
Vol 14 (20) ◽  
pp. 6065
Author(s):  
Wangxi Fan ◽  
Xiuqin Fu ◽  
Zefang Li ◽  
Junfei Ou ◽  
Zhou Yang ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Contact Angle ◽  
Tensile Strength ◽  
Wear Resistance ◽  
Biomedical Applications ◽  
Ultrahigh Molecular Weight Polyethylene ◽  
In Vitro Experiments ◽  
Ultrahigh Molecular Weight ◽  
Uhmwpe Composite

Ultrahigh molecular weight polyethylene (UHMWPE) materials have been prevalent joint replacement materials for more than 45 years because of their excellent biocompatibility and wear resistance. In this study, functionalized activated nanocarbon (FANC) was prepared by grafting maleic anhydride polyethylene onto acid-treated activated nanocarbon. A novel porous UHMWPE composite was prepared by incorporating the appropriate amount of FANC and pore-forming agents during the hot-pressing process for medical UHMWPE powder. The experimental results showed that the best prepared porous UHMWPE/FANC exhibited appropriate tensile strength, porosity, and excellent hydrophilicity, with a contact angle of 65.9°. In vitro experiments showed that the porous UHMWPE/FANC had excellent biocompatibility, which is due to its porous structure and hydrophilicity caused by FANC. This study demonstrates the potential viability for our porous UHMWPE/FANC to be used as cartilage replacement material for biomedical applications.

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