Novel Application of Polyelectrolyte Multilayers as Nanoscopic Closures with Hermetic Sealing

2012 ◽  
Vol 4 (3) ◽  
pp. 1620-1628 ◽  
Author(s):  
Stephanie A. Marcott ◽  
Sena Ada ◽  
Phillip Gibson ◽  
Terri A. Camesano ◽  
R. Nagarajan
Keyword(s):  
Polyelectrolyte Multilayers ◽  
Hermetic Sealing

Low Temperature Al-Al Thermo-compression Bonding with Sn Oxidation Protect Layer for Wafer-level Hermetic Sealing

2016 ◽  
Vol 136 (6) ◽  
pp. 237-243 ◽  
Author(s):  
Shiro Satoh ◽  
Hideyuki Fukushi ◽  
Masayoshi Esashi ◽  
Shuji Tanaka
Keyword(s):  
Low Temperature ◽  
Wafer Level ◽  
Hermetic Sealing

Shape Measurement of Canned Food to Verify Hermetic Sealing

2012 ◽  
Vol E95.C (10) ◽  
pp. 1662-1665
Author(s):  
Ryosuke SUGA ◽  
Shigenori TAKANO ◽  
Takenori YASUZUMI ◽  
Taichi IJUIN ◽  
Tetsuya TAKATOMI ◽  
...  
Keyword(s):  
Shape Measurement ◽  
Canned Food ◽  
Hermetic Sealing

120-GHz-Band Amplifier Module with Hermetic Sealing Structure for 10-Gbit/s Wireless System

2014 ◽  
Vol E97.C (6) ◽  
pp. 583-591
Author(s):  
Hiroyuki TAKAHASHI ◽  
Toshihiko KOSUGI ◽  
Akihiko HIRATA ◽  
Jun TAKEUCHI ◽  
Koichi MURATA ◽  
...  
Keyword(s):  
Wireless System ◽  
Hermetic Sealing

scholarly journals Strengthening Thermal Stability in V2O5-ZnO-BaO-B2O3-M(PO3)n Glass System (M = Al, Mg) for Laser Sealing Applications

2021 ◽  
Vol 11 (10) ◽  
pp. 4603
Author(s):  
Soyoung Kim ◽  
Karam Han ◽  
Seonhoon Kim ◽  
Linganna Kadathala ◽  
Jinhyeok Kim ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Thermal Expansion ◽  
Bond Strength ◽  
Coefficient Of Thermal Expansion ◽  
Glass Frit ◽  
Glass System ◽  
Fiber Types ◽  
Hermetic Sealing ◽  
Doped Glasses ◽  
Glass Panels

Today, the most common way of laser sealing is using a glass frit paste and screen printer. Laser sealing using glass frit paste has some problems, such as pores, nonuniform height, imperfect hermetic sealing, etc. In order to overcome these problems, sealing using fiber types of sealant is attractive for packaging devices. In this work, (70-x)V2O5-5ZnO-22BaO-3B2O3-xM(PO3)n glasses (mol%) incorporated with xM(PO3)n concentration (where M = Mg, Al, n = 2, 3, respectively) were fabricated and their thermal, thermomechanical, and structural properties were investigated. Most importantly, for this type of sealing, the glass should have a thermal stability (ΔT) of ≥80 °C and the coefficient of thermal expansion (CTE) between the glass and panel should be 1.0 ppm/°C. The highest thermal stability ΔT of the order of 93.2 °C and 112.9 °C was obtained for the 15 mol% of Mg(PO3)2 and Al(PO3)3 doped glasses, respectively. This reveals that the bond strength and connectivity is more strongly improved by trivalent Al(PO3)3. The CTE of a (70-x)V2O5-5ZnO-22BaO-3B2O3-xAl(PO3)3 glass system (mol%) (where x = 5–15, mol%) is in the range of 9.5–15.5 (×10−6/K), which is comparable with the CTE (9–10 (×10−6/K)) of commercial DSSC glass panels. Based on the results, the studied glass systems are considered to be suitable for laser sealing using fiber types of sealant.

scholarly journals Half-life modeling of basic fibroblast growth factor released from growth factor-eluting polyelectrolyte multilayers

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ivan Ding ◽  
Amy M. Peterson
Keyword(s):  
Cell Culture ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Half Life ◽  
Cell Types ◽  
Polyelectrolyte Multilayers ◽  
Enzyme Linked Immunosorbent Assay ◽  
Fibroblast Growth ◽  
Cell Culture Study

AbstractGrowth factor-eluting polymer systems have been widely reported to improve cell and tissue outcomes; however, measurements of actual growth factor concentration in cell culture conditions are limited. The problem is compounded by a lack of knowledge of growth factor half-lives, which impedes efforts to determine real-time growth factor concentrations. In this work, the half-life of basic fibroblast growth factor (FGF2) was determined using enzyme linked immunosorbent assay (ELISA). FGF2 release from polyelectrolyte multilayers (PEMs) was measured and the data was fit to a simple degradation model, allowing for the determination of FGF2 concentrations between 2 and 4 days of culture time. After the first hour, the FGF2 concentration for PEMs assembled at pH = 4 ranged from 2.67 ng/mL to 5.76 ng/mL, while for PEMs assembled at pH = 5, the concentration ranged from 0.62 ng/mL to 2.12 ng/mL. CRL-2352 fibroblasts were cultured on PEMs assembled at pH = 4 and pH = 5. After 2 days, the FGF2-eluting PEM conditions showed improved cell count and spreading. After 4 days, only the pH = 4 assembly condition had higher cells counts, while the PEM assembled at pH = 5 and PEM with no FGF2 showed increased spreading. Overall, the half-life model and cell culture study provide optimal concentration ranges for fibroblast proliferation and a framework for understanding how temporal FGF2 concentration may affect other cell types.

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