Composites of Aminodextran-Coated Fe3O4 Nanoparticles and Graphene Oxide for Cellular Magnetic Resonance Imaging

2011 ◽  
Vol 3 (10) ◽  
pp. 4085-4091 ◽  
Author(s):  
Weihong Chen ◽  
Peiwei Yi ◽  
Yi Zhang ◽  
Liming Zhang ◽  
Zongwu Deng ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Graphene Oxide ◽  
Magnetic Resonance ◽  
Fe3o4 Nanoparticles ◽  
Resonance Imaging

Superparamagnetic Fe3O4 Nanoparticles: Synthesis by Thermal Decomposition of Iron(III) Glucuronate and Application in Magnetic Resonance Imaging

2016 ◽  
Vol 8 (11) ◽  
pp. 7238-7247 ◽  
Author(s):  
Vitalii Patsula ◽  
Lucie Kosinová ◽  
Marija Lovrić ◽  
Lejla Ferhatovic Hamzić ◽  
Mariia Rabyk ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Thermal Decomposition ◽  
Magnetic Resonance ◽  
Fe3o4 Nanoparticles ◽  
Resonance Imaging ◽  
Nanoparticles Synthesis

Ultrafine graphene oxide–CoFe2O4 nanoparticle composite as T1 and T2 contrast agent for magnetic resonance imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (21) ◽  
pp. 17423-17429 ◽  
Author(s):  
N. Venkatesha ◽  
Pavan Poojar ◽  
R. Ashwini ◽  
Yasrib Qurishi ◽  
Sairam Geethanath ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Graphene Oxide ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Synthesis Method ◽  
Resonance Imaging ◽  
T1 And T2 ◽  
Nanoparticle Composites

Graphene oxide–CoFe2O4 nanoparticle composites were synthesized using a two step synthesis method in which graphene oxide was initially synthesized followed by precipitation of CoFe2O4 nanoparticles in a reaction mixture containing graphene oxide.

scholarly journals Microwave-Assisted Synthesis of SPION-Reduced Graphene Oxide Hybrids for Magnetic Resonance Imaging (MRI)

Nanomaterials ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1364 ◽  
Author(s):  
Marina Llenas ◽  
Stefania Sandoval ◽  
Pedro M. Costa ◽  
Judith Oró-Solé ◽  
Silvia Lope-Piedrafita ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Graphene Oxide ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Reduced Graphene Oxide ◽  
Resonance Imaging ◽  
Microwave Assisted ◽  
Reduced Graphene ◽  
Graphene Derivatives ◽  
Magnetic Resonance Imaging Mri

Magnetic resonance imaging (MRI) is a useful tool for disease diagnosis and treatment monitoring. Superparamagnetic iron oxide nanoparticles (SPION) show good performance as transverse relaxation (T2) contrast agents, thus facilitating the interpretation of the acquired images. Attachment of SPION onto nanocarriers prevents their agglomeration, improving the circulation time and efficiency. Graphene derivatives, such as graphene oxide (GO) and reduced graphene oxide (RGO), are appealing nanocarriers since they have both high surface area and functional moieties that make them ideal substrates for the attachment of nanoparticles. We have employed a fast, simple and environmentally friendly microwave-assisted approach for the synthesis of SPION-RGO hybrids. Different iron precursor/GO ratios were used leading to SPION, with a median diameter of 7.1 nm, homogeneously distributed along the RGO surface. Good relaxivity (r2*) values were obtained in MRI studies and no significant toxicity was detected within in vitro tests following GL261 glioma and J774 macrophage-like cells for 24 h with SPION-RGO, demonstrating the applicability of the hybrids as T2-weighted MRI contrast agents.

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