scholarly journals Poly(aniline) Nanowires in Sol–Gel Coated ITO: A pH-Responsive Substrate for Planar Supported Lipid Bilayers

2011 ◽  
Vol 3 (7) ◽  
pp. 2677-2685 ◽  
Author(s):  
Chenhao Ge ◽  
Kristina S. Orosz ◽  
Neal R. Armstrong ◽  
S. Scott Saavedra
Keyword(s):  
Lipid Bilayers ◽  
Sol Gel ◽  
Supported Lipid Bilayers ◽  
Ph Responsive ◽  
Poly Aniline

Supported Lipid Bilayers on Spacious and pH-Responsive Polymer Cushions with Varied Hydrophilicity

2008 ◽  
Vol 112 (20) ◽  
pp. 6373-6378 ◽  
Author(s):  
Lars Renner ◽  
Toshihisa Osaki ◽  
Salvatore Chiantia ◽  
Petra Schwille ◽  
Tilo Pompe ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Supported Lipid Bilayers ◽  
Ph Responsive ◽  
Responsive Polymer

scholarly journals Facile Formation of Highly Mobile Supported Lipid Bilayers on Surface-Quaternized pH-Responsive Polymer Brushes

2015 ◽  
Vol 48 (9) ◽  
pp. 3095-3103 ◽  
Author(s):  
N. Cheng ◽  
P. Bao ◽  
S. D. Evans ◽  
G. J. Leggett ◽  
S. P. Armes
Keyword(s):  
Lipid Bilayers ◽  
Polymer Brushes ◽  
Supported Lipid Bilayers ◽  
Ph Responsive ◽  
Responsive Polymer

scholarly journals ITO/Poly(Aniline)/Sol-Gel Glass: An Optically Transparent, pH-Responsive Substrate for Supported Lipid Bilayers

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Ahmed Al-Obeidi ◽  
Chenhao Ge ◽  
Kristina S. Orosz ◽  
S. Scott Saavedra
Keyword(s):  
Lipid Bilayers ◽  
Indium Tin Oxide ◽  
Sol Gel ◽  
Pani Film ◽  
Ph Response ◽  
Ito Electrode ◽  
Gel Layer ◽  
Optically Transparent ◽  
Lipid Diffusion ◽  
Poly Aniline

Described here is fabrication of a pH-sensitive, optically transparent transducer composed of a planar indium-tin oxide (ITO) electrode overcoated with a poly(aniline) (PANI) thin film and a porous sol-gel layer. Adsorption of the PANI film renders the ITO electrode sensitive to pH, whereas the sol-gel spin-coated layer makes the upper surface compatible with fusion of phospholipid vesicles to form a planar supported lipid bilayer (PSLB). The response to changes in the pH of the buffer contacting the sol-gel/PANI/ITO electrode is pseudo-Nernstian with a slope of 52 mV/pH over a pH range of 4–9. Vesicle fusion forms a laterally continuous PSLB on the upper sol-gel surface that is fluid with a lateral lipid diffusion coefficient of 2.2 μm2/s measured by fluorescence recovery after photobleaching. Due to its lateral continuity and lack of defects, the PSLB blocks the pH response of the underlying electrode to changes in the pH of the overlying buffer. This architecture is simpler to fabricate than previously reported ITO electrodes derivatized for PSLB formation and should be useful for optical monitoring of proton transport across supported membranes derivatized with ionophores and ion channels.

Influence of Brain Gangliosides on the Formation and Properties of Supported Lipid Bilayers for Binding Kinetics Studies

2018 ◽  
Author(s):  
Luke Jordan ◽  
Nathan Wittenberg
Keyword(s):  
Lipid Bilayers ◽  
Binding Kinetics ◽  
Supported Lipid Bilayers ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
Supported Lipid Bilayer ◽  
Head Groups ◽  
Lipid Diffusion ◽  
Kinetics Of ◽  
Brain Gangliosides

This is a comprehensive study of the effects of the four major brain gangliosides (GM1, GD1b, GD1a, and GT1b) on the adsorption and rupture of phospholipid vesicles on SiO2 surfaces for the formation of supported lipid bilayer (SLB) membranes. Using quartz crystal microbalance with dissipation monitoring (QCM-D) we show that gangliosides GD1a and GT1b significantly slow the SLB formation process, whereas GM1 and GD1b have smaller effects. This is likely due to the net ganglioside charge as well as the positions of acidic sugar groups on ganglioside glycan head groups. Data is included that shows calcium can accelerate the formation of ganglioside-rich SLBs. Using fluorescence recovery after photobleaching (FRAP) we also show that the presence of gangliosides significantly reduces lipid diffusion coefficients in SLBs in a concentration-dependent manner. Finally, using QCM-D and GD1a-rich SLB membranes we measure the binding kinetics of an anti-GD1a antibody that has similarities to a monoclonal antibody that is a hallmark of a variant of Guillain-Barre syndrome.

scholarly journals Silica nanoparticle supported lipid bilayers for gene delivery

2009 ◽  
pp. 5100 ◽  
Author(s):  
Juewen Liu ◽  
Alison Stace-Naughton ◽  
C. Jeffrey Brinker
Keyword(s):  
Gene Delivery ◽  
Lipid Bilayers ◽  
Silica Nanoparticle ◽  
Supported Lipid Bilayers

scholarly journals Formation of Supported Lipid Bilayers Derived from Vesicles of Various Compositional Complexity on Conducting Polymer/Silica Substrates

Langmuir ◽  
2021 ◽  
Author(s):  
Hanna Ulmefors ◽  
Josefin Nissa ◽  
Hudson Pace ◽  
Olov Wahlsten ◽  
Anders Gunnarsson ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Conducting Polymer ◽  
Supported Lipid Bilayers ◽  
Silica Substrates

scholarly journals Delivery of Ricin Toxin A-Chain by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers

2012 ◽  
Vol 1 (3) ◽  
pp. 348-353 ◽  
Author(s):  
Katharine Epler ◽  
David Padilla ◽  
Genevieve Phillips ◽  
Peter Crowder ◽  
Robert Castillo ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Lipid Bilayers ◽  
Silica Nanoparticle ◽  
Supported Lipid Bilayers ◽  
Toxin A ◽  
Mesoporous Silica Nanoparticle ◽  
Ricin Toxin ◽  
A Chain
Sign in / Sign up

Export Citation Format

Share Document