Toward Synthetic Biology Strategies for Adipic Acid Production: An in SilicoTool for Combined Thermodynamics and Stoichiometric Analysis of Metabolic Networks

2017 ◽  
Vol 7 (2) ◽  
pp. 490-509 ◽  
Author(s):  
Nils J. H. Averesch ◽  
Verónica S. Martínez ◽  
Lars K. Nielsen ◽  
Jens O. Krömer
Keyword(s):  
Synthetic Biology ◽  
Adipic Acid ◽  
Acid Production ◽  
Metabolic Networks ◽  
Stoichiometric Analysis

scholarly journals Artificial Biosynthetic Pathway for an Unnatural Terpenoid with an Iridiumcontaining P450

2020 ◽  
Author(s):  
Jing Huang ◽  
Zhennan Liu ◽  
brandon bloomer ◽  
Douglas Clark ◽  
Aindrila Mukhopadhyay ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Synthetic Biology ◽  
Chemical Reactions ◽  
Biosynthetic Pathway ◽  
Metabolic Networks ◽  
Complex Molecules ◽  
Whole Cells ◽  
Porphyrin Complex ◽  
Heme Transport ◽  
Artificial Metalloenzymes

<div>Synthetic biology enables microbial hosts to produce complex molecules that are</div><div>otherwise produced by organisms that are rare or difficult to cultivate, but the structures of these</div><div>molecules are limited to chemical reactions catalyzed by natural enzymes. The integration of</div><div>artificial metalloenzymes (ArMs) that catalyze abiotic reactions into metabolic networks could</div><div>broaden the cache of molecules produced biosynthetically by microorgansms. We report the</div><div>assembly of an ArM containing an iridium-porphyrin complex in the cytoplasm of a terpene</div><div>producing Escherichia coli by a heterologous heme transport machinery, and insertion of this ArM</div><div>into a natural biosynthetic pathway to produce an unnatural terpenoid. This work shows that</div><div>synthetic biology and synthetic chemistry, incorporated together in whole cells, can produce</div><div>molecules previously inaccessible to nature.</div>

Cobalt-Vanadyl mixed polyoxometallates as new catalysts for green adipic acid production

2021 ◽  
Author(s):  
Sihem Mouanni ◽  
Dahbia Amitouche ◽  
Tassadit Mazari ◽  
Abdenour Boumechhour ◽  
Cherifa Rabia
Keyword(s):  
Adipic Acid ◽  
Acid Production

scholarly journals Bio Adipic Acid Production from Sodium Muconate and Muconic Acid: A Comparison of two Systems

ChemCatChem ◽  
2019 ◽  
Vol 11 (13) ◽  
pp. 3075-3084 ◽  
Author(s):  
Sofia Capelli ◽  
Davide Motta ◽  
Claudio Evangelisti ◽  
Nikolaos Dimitratos ◽  
Laura Prati ◽  
...  
Keyword(s):  
Adipic Acid ◽  
Acid Production ◽  
Muconic Acid ◽  
Two Systems

scholarly journals Advanced Stoichiometric Analysis of Metabolic Networks of Mammalian Systems

2011 ◽  
Vol 39 (6) ◽  
pp. 511-534 ◽  
Author(s):  
Mehmet A. Orman ◽  
Francois Berthiaume ◽  
Ioannis P. Androulakis ◽  
Marianthi G. Ierapetritou
Keyword(s):  
Metabolic Networks ◽  
Stoichiometric Analysis

scholarly journals Adipic Acid Production via Metal-Free Selective Hydrogenolysis of Biomass-Derived Tetrahydrofuran-2,5-Dicarboxylic Acid

ACS Catalysis ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. 6619-6634 ◽  
Author(s):  
Matthew J. Gilkey ◽  
Alexander V. Mironenko ◽  
Dionisios G. Vlachos ◽  
Bingjun Xu
Keyword(s):  
Dicarboxylic Acid ◽  
Adipic Acid ◽  
Acid Production ◽  
Metal Free ◽  
Selective Hydrogenolysis

scholarly journals Adipic acid tolerance screening for potential adipic acid production hosts

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Emma Karlsson ◽  
Valeria Mapelli ◽  
Lisbeth Olsson
Keyword(s):  
Adipic Acid ◽  
Acid Production ◽  
Acid Tolerance
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